RELAPSTAPH: Recurrent S. Aureus Infections in Osteoarticular Infections
Study Details
Study Description
Brief Summary
Staphylococcus aureus osteoarticular infections, in particular those associated with the presence of implant, relapse in 20% of cases. Currently, the reasons for these relapses are poorly understood, whether on the microbiological or clinical side.
The aim of this study is to improve knowledge on persistence of mechanisms of S. aureus
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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relapse due to S. aureus patients having had an initial infection due to S. aureus and who present a relapse with persistence of S. aureus |
Other: relapse due to S. aureus
to find out if it is the same S. aureus in both infections
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Outcome Measures
Primary Outcome Measures
- rate of patients having had an osteoarticular infection due to S. aureus [between 2015 and 2020]
proportion of patients having had an osteoarticular infection due to S. aureus
- Description of patients having had an osteoarticular infection due to S. aureus [between 2015 and 2020]
type of patients: age, BMI, comorbidities...
- Description of Bone and Joint Iinfection/Prosthesis Joint Infection [between 2015 and 2020]
implant or prosthesis or not, acute/ chronic, bacteriology
Secondary Outcome Measures
- rate of patients having had a relapse due to persistence of S. aureus [between 2015 and 2020]
proportion of patients having had an osteoarticular infection due persistence of S. aureus
- rate of S. aureus strain identical between the initial episode and the relapse [between 2015 and 2020]
proportion of relapse due to the same strain of S. aureus than in the initial episode
Eligibility Criteria
Criteria
Inclusion Criteria:
- patients having had an osteoarticular infection with or without material due to S. aureus presenting a recurrence of S. aureus infection
Exclusion Criteria:
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Hospices Civils de Lyon | Lyon | France | 69004 |
Sponsors and Collaborators
- Hospices Civils de Lyon
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- 281