THE RELATIONSHIP OF CRP/ALBUMIN RATIO LEVEL AND PROGNOSIS IN PREGNANT COVID-19 PATIENTS

Sponsor
Adiyaman University Research Hospital (Other)
Overall Status
Active, not recruiting
CT.gov ID
NCT05242172
Collaborator
(none)
127
Enrollment
1
Location
1.4
Anticipated Duration (Months)
87.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The CRP/albumin ratio (CAR) is a recently defined parameter which represents the ratio of a positive acute phase reactant to a negative acute phase reactant. Recent studies have shown that the CRP/albumin ratio is a biomarker with prognostic value for various inflammatory disorders and serious diseases. With this study it is aimed to investigate the effect of CRP/albumin ratio in predicting the severity and prognosis of the disease in pregnant patients with more severe Covid-19 infection.

Condition or DiseaseIntervention/TreatmentPhase
  • Diagnostic Test: CRP/Albumin ratio

Detailed Description

Pregnant women are more susceptible to viral infections affecting the respiratory tract than non-pregnant women. Similar to non-pregnant patients, Covid-19 infection occurs with non-specific symptoms in pregnant patients. A computed tomography (CT) scan of lungs and several laboratory parameters are used to predict the prognosis of this infection, which starts with non-specific findings. Although it has been demonstrated that low-dose lung CT can be used safely in pregnant women, both clinicians and pregnant women tend to avoid tomography imaging due to its teratogenic effects

The CRP/albumin ratio (CAR) is a recently defined parameter which represents the ratio of a positive acute phase reactant to a negative acute phase reactant. It is an indicator of both the inflammatory state and the nutritional state, simultaneously. Recent studies have shown that the CRP/albumin ratio is a biomarker with prognostic value for various inflammatory disorders and serious diseases. With this study it is aimed to investigate the effect of CRP/albumin ratio in predicting the severity and prognosis of the disease in pregnant patients with more severe Covid-19 infection.

Study Design

Study Type:
Observational
Actual Enrollment :
127 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
THE RELATIONSHIP OF CRP/ALBUMIN RATIO LEVEL AND PROGNOSIS IN PREGNANT COVID-19 PATIENTS
Actual Study Start Date :
Jan 15, 2022
Actual Primary Completion Date :
Feb 15, 2022
Anticipated Study Completion Date :
Feb 28, 2022

Outcome Measures

Primary Outcome Measures

  1. CRP/Albumin ratio [First day of hospital stay]

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 65 Years
Sexes Eligible for Study:
Female
Inclusion Criteria:
  • Covid PCR test positive patients

  • Pregnant

Exclusion Criteria:
  • Covid PCR test negative

  • Missed data

Contacts and Locations

Locations

SiteCityStateCountryPostal Code
1Adıyaman Training and Research HospitalAdıyamanTurkey02200

Sponsors and Collaborators

  • Adiyaman University Research Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Nezir Yılmaz, Principal investigator, Adiyaman University Research Hospital
ClinicalTrials.gov Identifier:
NCT05242172
Other Study ID Numbers:
  • 14/12/2021-2021/10-19
First Posted:
Feb 16, 2022
Last Update Posted:
Feb 16, 2022
Last Verified:
Jan 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Feb 16, 2022