Retained Lens Fragments After Phacoemulsification
Study Details
Study Description
Brief Summary
The purpose of this study is to investigate postoperative events in patients noted to have retained nuclear fragments in the anterior vitreous during routine phacoemulsification and in those who did not.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
In this study, we investigate whether presence of retained nuclear fragments in the anterior vitreous noted during uncomplicated cataract surgery is associated with higher incidence of postoperative adverse events. We will be assessing events including cystoid macular edema, iritis, elevated intraocular pressure, and retinal detachment.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Cataract Phacoemulsification Subjects will be recruited serially from eligible candidates on the basis of presentation for cataract evaluation and subsequent cataract surgery with phacoemulsification. |
Procedure: Phacoemulsification
Subjects will be recruited serially from eligible candidates on the basis of presentation for cataract evaluation and subsequent cataract surgery with phacoemulsification.
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Outcome Measures
Primary Outcome Measures
- Macular edema [1 month postoperatively]
Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 1 month postoperatively
Secondary Outcome Measures
- Intraocular inflammation [1 month postoperativley]
Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 1 month postoperatively
- Elevated intraocular pressure [1 month postoperatively]
Proportion of eyes with intraocular pressure increase requiring medical or surgery treatment at 1 month postoperatively
- Macular Edema [1 week postoperatively]
Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 1 week postoperatively
- Intraocular Inflammation [1 week postoperatively]
Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 1 week postoperatively
- Elevated Intraocular Pressure [1 week postoperatively]
Proportion of eyes with intraocular pressure increase requiring medical or surgery treatment at 1 week postoperatively
- Macular Edema [3 months postoperatively]
Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 3 months postoperatively
- Intraocular Inflammation [3 months]
Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 3 months postoperatively
Other Outcome Measures
- Surgical Complications [Intraoperatively]
Proportion of eyes with surgical adverse events.
Eligibility Criteria
Criteria
Inclusion Criteria:
- Routine cataract surgery with phacoemulsification
Exclusion Criteria:
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Pre-existing macular edema
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Active uveitis
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Intraocular exclusion surgeries
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Significant ocular trauma
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Evidence of phacodonesis or zonular weakness .
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Ophthalmic Consultants, Corneal and Refractive Surgery Associates, PC | New York | New York | United States | 10003 |
Sponsors and Collaborators
- Ophthalmic Consultants, Corneal and Refractive Surgery Associates, PC
Investigators
- Principal Investigator: David Ritterband, MD, Ophthalmic Consultants, Cornea and Refractive Surgery Assoicates, PC
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 12.08