SARS-CoV-2 /COVID-19 Admission Screening in a University Hospital Setting

• Sponsor: University Hospital, Basel, Switzerland (Other)
• Overall Status: Completed
• CT.gov ID: NCT04519372
• Collaborator: (none)
• Enrollment: 4,099
• Location: 1
• Actual Duration (Months): 12
• Patients Per Site Per Month: 342.8

Study Details

Study Description

Brief Summary

The proportion of asymptomatic carriers of SARS-CoV-2 remains elusive, so the potential benefit of systematic screening during the SARS-CoV-2-pandemic is controversial. We investigate the proportion of asymptomatic inpatients who were identified by systematic screening for SARS-CoV-2 upon hospital admission.

Adult patients admitted to the University Hospital Basel from 01.04.-14.06.2020 were routinely tested for SARS-CoV-2 within 72 hours of admission by nasopharyngeal swabs.

Each patient screened during the study period was retrospectively classified symptomatic or asymptomatic for COVID-19 based on medical chart review.

Condition or Disease	Intervention/Treatment	Phase
Covid19; SARS-CoV-2	Diagnostic Test: Testing for SARS-CoV-2

Study Design

• Study Type: Observational
• Actual Enrollment: 4099 participants
• Observational Model: Other
• Time Perspective: Retrospective
• Official Title: SARS-CoV-2 /COVID-19 Admission Screening in a University Hospital Setting (Covid-Screen Quality Control Study)
• Actual Study Start Date: Apr 1, 2020
• Actual Primary Completion Date: Jun 14, 2020
• Actual Study Completion Date: Mar 31, 2021

Outcome Measures

Primary Outcome Measures

1. Proportion of SARS-CoV-2 -infected patients [01.04.2020-14.06.2020]

   We aim to determine the proportion of SARS-CoV-2-infected patients detected by systematic at-admission screening

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• The patient population is defined as all adult patients hospitalized in the University Hospital Basel from April 1st, 2020 to June 14th, 2020.

Exclusion Criteria:

• Outpatients

• Patients with SARS-CoV-2 screening in the outpatient test center

• Patients with a SARS-CoV-2 test more than 72 hours before hospital admission

• Test not performed (for any reason)

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University Hospital Basel, Division of Infectious Diseases and Hospital Epidemiology	Basel		Switzerland	4031

Sponsors and Collaborators

• University Hospital, Basel, Switzerland

Investigators

• Principal Investigator: Sarah Tschudin-Sutter, Prof. Dr. MD, University Hospital Basel, Division of Infectious Diseases and Hospital Epidemiology

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University Hospital, Basel, Switzerland
• ClinicalTrials.gov Identifier: NCT04519372
• Other Study ID Numbers: 2020-00808
• First Posted: Aug 19, 2020
• Last Update Posted: May 18, 2021
• Last Verified: May 1, 2021

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by University Hospital, Basel, Switzerland: Screening; asymptomatic
• Additional relevant MeSH terms: COVID-19

Study Results

No Results Posted as of May 18, 2021