Sensory Feedback for Touch and Proprioception With Prosthetic Limbs
Study Details
Study Description
Brief Summary
Upper limb amputation is a devastating injury that leaves many thousands of typically young and active individuals in the US to rely on artificial arms and hands to help restore their lost function. The investigators research is focused on helping these individuals to feel where their prosthetic limbs are moving without having to look at them by developing devices and approaches to provide sensory feedback of limb movement through the nerves that once served the missing limb.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
In the investigators research the investigators seek to understand the organization and (function/operation) of sensory neural systems in order to develop methods for restoring function to injured populations. One of the primary focus areas of the investigators research is working to integrate physiologically relevant sensory feedback with prosthetic limbs. To this end the investigators employ a variety of approaches that interweave disciplines such as electrophysiology, psychophysics, biomedical engineering and cognition. The investigators research team is composed of an interconnected and communicative network of clinicians, engineers, and scientists. This helps us to provide pathways from basic science discoveries that can be used to address clinical needs with transition directly to patient care.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Upper Extremity Amputee Robust custom tactor to facilitate embodiment and proprioception |
Device: Tactor array
|
| Able Bodied Bypass tactor |
Device: Bypass Tactor
|
Outcome Measures
Primary Outcome Measures
- Embodiment of the Prosthetic limb [Ten months]
Visual loading for fine motor tasks,questionnaires, and residual limb temperature will be assessed after 10 months of in home every day use of a custom robust tactor array for sensory feedback.
Secondary Outcome Measures
- Investigate the perceptions of limb movement [6 months]
Test how closely both targeted reinnervation amputees and able bodied study participants are able to interpret limb movement using the kinesthetic perceptual illusion and physiologically relevant kinesthetic feedback.
Eligibility Criteria
Criteria
Inclusion Criteria:
Amputee criteria:
-
Must be over 18 years of age
-
Must be upper extremity amputee who has undergone targeted sensory reinnervation.
Able Bodied participants:
- Must be over 18 years of age
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Rehabilitation Institute of Chicago | Chicago | Illinois | United States | 60611 |
| 2 | Louis Stokes VA Medical Center | Cleveland | Ohio | United States | 44106 |
| 3 | Cleveland Clinic Lerner Research Institute | Cleveland | Ohio | United States | 44195 |
| 4 | University of Alberta Glenrose Rehabilitation Hospital | Edmonton | Alberta | Canada | T5B0B7 |
Sponsors and Collaborators
- Louis Stokes VA Medical Center
- National Institute of Neurological Disorders and Stroke (NINDS)
- National Institutes of Health (NIH)
- The Cleveland Clinic
- HDT Global
- University of Alberta
- Shirley Ryan AbilityLab
- Defense Advanced Research Projects Agency
Investigators
- Principal Investigator: Paul Marasco, PhD, Louis Stokes VA Medical Center, Cleveland Clinic Lerner Research Institute
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- 11061-H39
- R01NS081710-01