The Serum Lipid Profiles in ITP: a Retrospective Study
Study Details
Study Description
Brief Summary
The project was retrospectively undertaking by Qilu Hospital of Shandong University in China. In order to investigate the correlations between platelet indices, serum lipids and bleeding symptoms in ITP.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Detailed Description
Background: Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease characterized by increased platelet destruction and impaired thrombopoiesis. Platelet indices changes depending on the morphology and volume of platelets. Serum lipids have been found to affect platelet formation and activity in certain diseases, thus induce the corresponding variation of platelet indices.
Objectives: To investigate the correlations between platelet indices, serum lipids and bleeding symptoms in ITP.
Methods: The clinical data from 457 ITP patients were retrospectively collected and analyzed, including platelet indices, serum lipids, hemorrhage and therapeutic regimen.
Study Design
Outcome Measures
Primary Outcome Measures
- Platelet count at 1 month after initial therapy [1 month]
Platelet count was tested at 1 month after initial therapy
Eligibility Criteria
Criteria
Inclusion Criteria:
- Meet the diagnostic criteria for immune thrombocytopenia.
Exclusion Criteria:
- (1) receiving platelet transfusion within 7 days or ITP-related medication within 3 months (2) treated with lipid-lowing agents, including statins, fibrates, niacin, bile sequestrant resins, ezetimibe and so on.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Qilu hospital of Shandong university | Jinan | Shandong | China | 273300 |
Sponsors and Collaborators
- Ming Hou
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- lipid in ITP