Effect of Oral Collagen Tripeptide on Skin Moisture and Wrinkles in Adult Women
Study Details
Study Description
Brief Summary
Comparison of a randomized, double-blind, and control-group study for the effect of oral ingestion of collagen tripeptides derived from fish on dermal moistures and wrinkles body fat reduction in participants
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Detailed Description
The aim is to investigate the effect of oral ingestion of collagen tripeptides derived from fish on dermal moistures and wrinkles body fat reduction in participants by a randomized, double-blind, and control-group study.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: CTP group 1,000 mg of collagen tripeptide (CTP) was orally administered per day for 12 weeks. |
Dietary Supplement: CTP
1,000 mg of CTP was orally administered per day for 12 weeks.
|
Placebo Comparator: Control group 1,000 mg of placebo (starch) was orally administered per day for 12 weeks |
Dietary Supplement: placebo (starch)
placebo (starch)
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Outcome Measures
Primary Outcome Measures
- changes in Transepidermal Waterloss by Tewameter [baseline, after 6 weeks, and after 12 weeks]
comparison between baseline, after 6 weeks, and after 12 weeks
Secondary Outcome Measures
- changes in skin wrinkling indices by Visiometer [baseline, after 6 weeks, and after 12 weeks]
comparison between baseline, after 6 weeks, and after 12 weeks
- skin elasticity by Cutometer [baseline, after 6 weeks, and after 12 weeks]
comparison between baseline, after 6 weeks, and after 12 weeks
- changes in hydration level of the skin surface by Corneometer [baseline, after 6 weeks, and after 12 weeks]
comparison between baseline, after 6 weeks, and after 12 weeks
Eligibility Criteria
Criteria
Inclusion Criteria:
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= 4 of Tewameter
Exclusion Criteria:
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Within the last 6 months, took skin surgery including cosmetic purpose
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Diabetic patients with poor glycemic control with a fasting blood glucose of 160 mg/dl or more
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Creatinine levels: more than twice the normal upper limit
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AST (GOT) or ALT (GPT) levels: more than twice the normal upper limit
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Uncontrolled hypertension
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sun allergy or sensitive skin
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functional cosmetics that affect dermal moistures and wrinkles within the last 3 months.
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If you have participated or are planning to participate in another clinical trial within the past month
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Alcohol abuser
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If they are pregnant or lactating or have a pregnancy plan during the clinical trial Those with allergic reactions to the constituent food
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Any person deemed inappropriate by the researcher for other reasons
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Integrated Research Institute for Natural Ingredients and Functional Foods | Yangsan | Korea, Republic of | 50612 |
Sponsors and Collaborators
- Pusan National University Yangsan Hospital
Investigators
- Principal Investigator: Sang Yeoup Lee, MD, Integrated Research Institute for Natural Ingredients and Functional Foods
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 02-2017-033