Sleep Hygiene, Sarcopenia, and Cognitive Function in Respiratory Disease
Study Details
Study Description
Brief Summary
We aim to clarify the relationship between sleep hygiene and the onset of sarcopenia or cognitive dysfunction using sleep time, arousal, and sleep quality as indicators in COPD or IPF patients, and clarify the effects of sleep hygiene on disease progression and life prognosis.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) have been reported to be associated with a high rate of sleep-related disorders such as insomnia, sleep-related hypoventilation, and sleep apnea syndrome.Sleep-related disorders cause symptoms such as daytime sleepiness, decreased ADL, and depression, which causes cognitive dysfunction. Both COPD and IPF have been reported to be associated with cognitive dysfunction. Recently, it has been focused on the relationship between sleep-related disorders and sarcopenia. The relationship between sleep hygiene, cognitive dysfunction, and sarcopenia in the patients with COPD or IPF is not well understood.
Study Design
Outcome Measures
Primary Outcome Measures
- Relationship between sleep time at study enrollment and onset of sarcopenia during follow-up period [Two years]
Secondary Outcome Measures
- Relationship between sleep time at study enrollment and the onset of mild cognitive impairment during follow-up period [Two years]
- Relationship between sleep efficiency, arousal at the time of study enrollment and the onset of sarcopenia and mild cognitive impairment during the follow-up period [Two years]
- Association of sleep time, sleep efficiency, arousal at the time of study enrollment and hospitalization and death due to COPD exacerbations or IPF exacerbations during follow-up period [Two years]
- Relationship between sleep time, sleep efficiency, arousal at the time of study enrollment and changes in grip strength, walking speed, skeletal muscle mass and cognitive function during follow-up period [Two years]
- Relationship between sleep time, sleep efficiency, arousal at the time of study enrollment and changes in grip strength, walking speed, skeletal muscle mass and cognitive function at the time of study enrollment [Two years]
- Factors associated with the onset of sarcopenia and mild cognitive impairment during follow-up period [Two years]
Eligibility Criteria
Criteria
Inclusion Criteria:
- Subjects with COPD or IPF.
Exclusion Criteria:
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Subjects who have been hospitalized for exacerbation of respiratory failure within 1 month of study participation
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Subjects who have already been diagnosed with sarcopenia or cognitive dysfunction
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Subjects receiving long-term oxygen therapy (LTOT) or non-invasive ventilation therapy (NIV)
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Subjects with obstructive sleep apnea who are indicated for continuous positive airway pressure (CPAP)
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Subjects with severe complications such as cardiovascular disease, liver disease, renal disease, malignancy, and neurological disease.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | National Hospital Organization Minami Kyoto Hospital | Joyo | Kyoto | Japan | 610-0113 |
Sponsors and Collaborators
- National Hospital Organization Minami Kyoto Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2020-32