Contribution of the Somatosensory System to Speech Perceptual Processing

Sponsor
Yale University (Other)
Overall Status
Recruiting
CT.gov ID
NCT04818021
Collaborator
McGill University (Other), National Institute on Deafness and Other Communication Disorders (NIDCD) (NIH)
160
1
4
60
2.7

Study Details

Study Description

Brief Summary

These studies test the hypothesis that the repeated pairing of somatosensory inputs with speech sounds, such as occurs during speech motor learning, results in changes to the perceptual classification of speech sounds.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Adaptation
  • Behavioral: Facial Skin Stretch
N/A

Detailed Description

This study will assess changes to the perceptual classification of speech sounds that are related to repeated pairing of somatosensory and auditory inputs (as would occur during speech motor learning). Before and after the training, base-line and post-training auditory perceptual performance will be examined in the absence of somatosensory stimulation, in order to evaluate the effects of the pairing on speech perception. Perceptual classification and speech motor learning will both be assessed on a 0 to 100 scale.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
160 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Contribution of the Somatosensory System to Speech Perceptual Processing Aim 3
Actual Study Start Date :
Aug 1, 2019
Anticipated Primary Completion Date :
Jan 31, 2024
Anticipated Study Completion Date :
Jul 31, 2024

Arms and Interventions

Arm Intervention/Treatment
Experimental: Adaptation to Altered Auditory Feedback

Adaptation to Altered Auditory Feedback

Behavioral: Adaptation
Sensorimotor adaptation in speech

Experimental: Adaptation to Altered Auditory Feedback + Forward Skin Stretch

Adaptation to Altered Auditory Feedback + Forward Skin Stretch

Behavioral: Adaptation
Sensorimotor adaptation in speech

Behavioral: Facial Skin Stretch
Facial skin stretch

Experimental: Adaptation to Altered Auditory Feedback + Backward Skin Stretch

Adaptation to Altered Auditory Feedback + Backward Skin Stretch

Behavioral: Adaptation
Sensorimotor adaptation in speech

Behavioral: Facial Skin Stretch
Facial skin stretch

Experimental: Speech Repetition Control

Speech Repetition Control

Behavioral: Adaptation
Sensorimotor adaptation in speech

Outcome Measures

Primary Outcome Measures

  1. Speech Motor Learning [Performance as measured at the end of learning (30 minute session)]

    Learning is assessed as the change in speech sounds (speech formant frequencies) on a 0 to 100 scale.

  2. Speech Perception [Perception is evaluated prior to and after perceptual training (30 minute session)]

    Auditory speech perception evaluates auditory classification and is assessed on a 0 to 100 scale. All conditions of skin stretch involve the same speech perception task.

Eligibility Criteria

Criteria

Ages Eligible for Study:
21 Years to 40 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • right handed adults

  • no known physical or neurological abnormalities

Exclusion Criteria:
  • patients with:

  • cardiac pacemaker

  • surgical clips or values on the heart

  • implants

  • metal or metallic fragments in any part of the body

  • pregnancy

  • claustrophobia

  • a personal or family history of epilepsy

  • currently taking antipsychotic drugs

  • currently taking antidepressant drugs

  • currently taking antianxiety drugs.

Contacts and Locations

Locations

Site City State Country Postal Code
1 McGill Univeristy Montréal Quebec Canada H3A1G1

Sponsors and Collaborators

  • Yale University
  • McGill University
  • National Institute on Deafness and Other Communication Disorders (NIDCD)

Investigators

  • Principal Investigator: David Ostry, Haskins Laboratories

Study Documents (Full-Text)

More Information

Publications

None provided.
Responsible Party:
Yale University
ClinicalTrials.gov Identifier:
NCT04818021
Other Study ID Numbers:
  • 2000025475_b
  • R01DC017439
First Posted:
Mar 26, 2021
Last Update Posted:
May 18, 2022
Last Verified:
May 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of May 18, 2022