Crowdsourcing to Reduce HIV Stigma Among Adolescents and Young Adults in Kazakhstan

Sponsor
Columbia University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05107401
Collaborator
National Institutes of Health (NIH) (NIH), Fogarty International Center of the National Institute of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH)
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Study Details

Study Description

Brief Summary

This project will assess whether a digital crowdsourced intervention can reduce HIV stigma and promote HIV self-testing among adolescents and young adults (AYA). NIH has emphasized the need for research on interventions to reduce HIV-associated stigma and its impact on the prevention and treatment of HIV/AIDS, particularly in low and middle income countries (LMICs). The proposed study has the highest public health significance: it uses a community-based participatory approach to engage local AYA to develop a digital crowdsourced HIV stigma reduction and self-testing intervention to reduce HIV stigma and increase HIV testing.

Study Aim 1: To develop a crowdsourced digital HIV stigma reduction and self-testing intervention targeting AYA in Kazakhstan. Using a community-based participatory approach that engages local adolescents and young adults (AYA) and youth organizations, we will launch a national crowdsourcing contest in which AYA will design multimedia content to reduce HIV stigma in order to promote HIV testing among peers.

Study Aim 2: To pilot test this crowdsourced HIV stigma reduction and self-testing intervention in a preliminary efficacy trial. We will assess the intervention's feasibility and acceptability and obtain preliminary estimates of its effects on decreasing HIV stigma (primary outcome) and increasing HIV testing (secondary outcome) among AYA in Kazakhstan who received the intervention compared to individuals who did not. Participants (n=168) will be randomized 1:1 to: 1) receive the winning multimedia crowdsourced HIV stigma reduction content and a link for HIV self-testing, or 2) receive standard Kazakhstan Ministry of Health HIV informational materials and a link for HIV self-testing.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults
N/A

Detailed Description

This project will assess whether a digital crowdsourced intervention can reduce HIV stigma and promote HIV self-testing among adolescents and young adults (AYA). Globally AYA are at increased risk for HIV acquisition. In Eastern Europe and Central Asia (EECA), new HIV infections among 15-24 year old AYA are expected to increase 28% by 2030. In Kazakhstan, one in four HIV infections occur among AYA. Despite the growing HIV burden among AYA in Kazakhstan, this population has some of the lowest HIV testing rates in the country, largely due to stigma. Yet few efforts in Kazakhstan address HIV stigma and the role it plays as a barrier to HIV testing. Digital technologies and crowdsourcing campaigns (i.e., engaging groups of AYA online to address public health challenges and share solutions) are scalable, cost-effective tools that can increase HIV testing services and reduce HIV stigma in low and middle income countries (LMICs) and other resource- constrained settings. Crowdsourcing may be particularly successful among AYA, given their high levels of social media use and technological literacy. Complementing the crowdsourcing approach, mailing HIV rapid test kits can enable AYA to avoid the stigma associated with attending the AIDS Center and overcome transportation barriers.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
168 participants
Allocation:
Randomized
Intervention Model:
Single Group Assignment
Intervention Model Description:
Participants will be randomized to receive the digital crowdsourced intervention or standard of care (existing HIV informational materials). We will examine effects of the intervention on reducing HIV stigma and increasing HIV testing.Participants will be randomized to receive the digital crowdsourced intervention or standard of care (existing HIV informational materials). We will examine effects of the intervention on reducing HIV stigma and increasing HIV testing.
Masking:
Single (Participant)
Primary Purpose:
Diagnostic
Official Title:
Reducing HIV Stigma to Increase HIV Testing Among Adolescents and Young Adults in Kazakhstan Using a Crowdsourcing Approach
Anticipated Study Start Date :
Jun 1, 2022
Anticipated Primary Completion Date :
May 1, 2023
Anticipated Study Completion Date :
May 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Experimental: Crowdsourced Intervention

The digital crowdsourced intervention will be presented to participants in the intervention arm.

Behavioral: Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults
Adolescents and young adults will participate in a crowdsourcing contest to create digital materials to reduce HIV stigma in order to increase HIV testing. Entries will be judged by a community judging panel and expert judging panel. Winning entries will be selected for the digital intervention and presented to participants in the intervention arm.

No Intervention: Standard of Care

Standard HIV informational materials currently used by the Kazakhstan Ministry of Health will be presented to participants in the control arm.

Outcome Measures

Primary Outcome Measures

  1. Mean score change in HIV Stigma Scale [Baseline and 3 months]

    This is to measure HIV stigma. The scale/questionnaire is comprised of 10 items on a 4-point Likert scale (score range from 4-40). Higher scores indicate higher levels of stigma. Outcome will be assessing in mean score change from baseline to 3 months follow-up.

Secondary Outcome Measures

  1. Uptake of HIV self-test [Up to 3 months]

    This is to measure HIV testing. The number is generated by whether an HIV self-test kit was ordered and is a dichotomous outcome (yes/no).

Eligibility Criteria

Criteria

Ages Eligible for Study:
16 Years to 24 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Age 16-24

  • Report previous sex with another individual

  • Reside in Kazakhstan

Exclusion Criteria:
  • Not willing to provide consent or not able to understand study procedures

Contacts and Locations

Locations

Site City State Country Postal Code
1 Columbia University Global Health Research Center of Central Asia Almaty Kazakhstan 050040

Sponsors and Collaborators

  • Columbia University
  • National Institutes of Health (NIH)
  • Fogarty International Center of the National Institute of Health
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Investigators

  • Principal Investigator: Alissa Davis, PhD, Columbia University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Alissa Davis, Assistant Professor of Social Work, School of Social Work, Columbia University
ClinicalTrials.gov Identifier:
NCT05107401
Other Study ID Numbers:
  • AAAT7871
  • R21TW012017
First Posted:
Nov 4, 2021
Last Update Posted:
Mar 8, 2022
Last Verified:
Mar 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Alissa Davis, Assistant Professor of Social Work, School of Social Work, Columbia University

Study Results

No Results Posted as of Mar 8, 2022