Structural Imaging Assisted Retinal Fluorescence Lifetime Imager (STARFLI)
Study Details
Study Description
Brief Summary
To investigate the feasibility of a combined OCT/FLIM device
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
To investigate the feasibility of a combined Optical coherence tomography/ Fluorescence Lifetime Measurement (OCT/FLIM) device.
Study Design
Outcome Measures
Primary Outcome Measures
- Feasibility of device [1 year]
We will organize and perform an observational study with the prototype OCT+FLIM device and contribute the acquired OCT/FLIM datasets from eyes of different age and status of the crystalline lens.
Secondary Outcome Measures
- To provide two key technology aspects of the project: [1 year]
A. The first will be to bring forward a novel registration strategy for calibrated OCT and FLIM modalities, so that these can be used in conjunction. B. The second will be to develop an image calibration and normalization method using the measured lens fluorescence lifetime and possibly also structural (OCT) information on lens and retina, so that data acquired by the device can be used across different patients in a consistent way.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Subject must be willing to give written informed consent
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Age: Patients and Probands 18 years or greater
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Both eyes will be assessed in the study
Exclusion Criteria:
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Patients not willing or able to sign informed consent
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Patients younger than 18 years
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Patients with epilepsy
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Department of Ophthalmology, Bern University Hospital, Bern, 3010 Bern, Switzerland | Bern | Switzerland | 3010 |
Sponsors and Collaborators
- University Hospital Inselspital, Berne
- Haag-Streit AG
- University of Bern
Investigators
- Study Chair: Martin S. Zinkenagel, Prof.Dr.Dr., Clinic director
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- STARFLI