Success of Inferior Alveolar Nerve Block in Women Taking Selective Serotonin Reuptake Inhibitors
Study Details
Study Description
Brief Summary
To evaluate the success of inferior alveolar nerve block (IANB) for mandibular molars with irreversible pulpitis in women under treatment with selective serotonin reuptake inhibitors (SSRIs).
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
Seventy patients with a diagnosis of symptomatic irreversible pulpitis in one mandibular molar were assigned to either SSRI users or SSRI non-users groups. SSRIs users were 45 women who take SSRIs referred for endodontic treatment from a psychiatric clinic to the clinic of the endodontic department of Isfahan University of Medical Sciences. SSRIs non-users were 45 women who did not take SSRIs referred for endodontic treatment to the same dental clinic. The protocol of the study was approved by the Ethics Committee of the university (no. 394867). Written informed consent was obtained from all the patients. The level of anxiety of the patients was determined by using the Corah Dental Anxiety Scale. The patients registered their baseline pain severity using a Heft-Parker visual analogue scale (HP-VAS). Two standard IANBs (1.8-mL cartridges) of 2% lidocaine with 1:100,000 epinephrine (Darupakhsh, Tehran, Iran) were administered to each patient. Fifteen minutes after injection, the teeth were isolated. Access cavity preparation was started. The patients was instructed by the same operator to mark his or her pain experienced during the access cavity preparation.
Study Design
Outcome Measures
Primary Outcome Measures
- the success rate of the IAN block [taking any type of SSRI for at least six weeks prior to the study]
Eligibility Criteria
Criteria
Inclusion Criteria:
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vital mandibular molar tooth
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diagnosis of symptomatic irreversible pulpitis
Exclusion Criteria:
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younger than 18 years old
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history of significant medical conditions
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allergies to local anesthetics or sulfites
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pregnancy
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active sites of pathosis in area of injection
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inability to give informed consent
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | School of Dentistry, Isfahan University of Medical Sciences | Isfahan | Iran, Islamic Republic of | 81747673461 |
Sponsors and Collaborators
- Isfahan University of Medical Sciences
Investigators
- Study Chair: Abbasali khademi, Isfahan University of Medical Sciences
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 394867