Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Sponsor

Mayo Clinic (Other)

Overall Status

Recruiting

CT.gov ID

NCT02613299

Collaborator

(none)

200

Enrollment

Location

Duration (Months)

2.4

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to determine whether radiation therapy decreases tumor size and tumor spread. The investigators will consent subjects that have been diagnosed with mesothelioma and will undergo radiation therapy followed by surgical resection as their standard of care. The investigators will collect data from past and future medical records as well as data regarding their health status for their lifetime by reviewing life status, treatment status and CT scans.

Condition or Disease	Intervention/Treatment	Phase
Mesothelioma Solitary Fibrous Tumor of the Pleura

Study Design

Study Type:

Observational

Anticipated Enrollment :

200 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Study Start Date :

Nov 1, 2015

Anticipated Primary Completion Date :

Dec 1, 2022

Anticipated Study Completion Date :

Dec 1, 2022

Outcome Measures

Primary Outcome Measures

Survival status upon review of patient records every 6 months [2 years]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Subject provides informed consent
Subject is >18 years of age
Subject is deemed competent for making medical decisions
Subject is scheduled to undergo radiation followed by extrapleural pneumonectomy.
Subject is a surgical candidate
A negative pregnancy test is required in women of child-bearing potential, as standard of care.