Taste Supra-thresholds Among a Sample of Depressed Egyptian Adult Under Anti-depressants Therapy
Study Details
Study Description
Brief Summary
Determine the taste intensity at supra-threshold among a sample of depressed Egyptian adults (age from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using filter paper disc(FPD) method using a psychophysical method through a scoring system.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
PECO
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P Population: depressed Egyptian adults under anti-depressants therapy
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E1 Exposure 1: Tricyclic antidepressants (Imipramine, Amitriptyline, Clomipramine HCL)
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E2 Exposure 2: Selective Serotonin Re-uptake inhibitors antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine)
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C control (non exposure) : non-pharmacological treatment ( psychotherapy)
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O Outcome: Determine the taste intensity at supra-threshold among these patients using a psychophysical method through a scoring system
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Exposure 1 commonly prescribed tricyclic antidepressants (Imipramine, Amitriptyline, Clomipramine HCL) administered for at least 3 months |
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Exposure 2 commonly prescribed Selective Serotonin Re-uptake inhibitors antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine) administered for at least 3 months |
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Non exposure Non-pharmacological treatment (psychotherapy) |
Outcome Measures
Primary Outcome Measures
- Taste intensity at supra-threshold [during a period of 3 months from February 2021 till April 2021]]
- C.M will assess the taste intensity at supra-threshold level on a 9 point vertical labeled scale (extremely strong, very strong, strong, slightly strong, neutral, slightly weak, weak , very weak, extremely weak) in which subjects indicate the intensity perceived when tasting a substance
Eligibility Criteria
Criteria
Inclusion Criteria:
- Depressed Egyptian adults under antidepressants therapy for at least 3 months/non-pharmacological treatment( psychotherapy) • Age from 20 to 50 years old
Exclusion Criteria:
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Antipsychotics
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Hypnotics
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Anticonvulsants
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Ages other than the mentioned • Olfactory dysfunction
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Chemosensory dysfunction
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Faculty of Dentistry, Cairo University | Cairo | Egypt |
Sponsors and Collaborators
- Cairo University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 18936