Thoracic Paravertebral Blocks Using a Combination of Ropivacaine and Dexmedetomidine
Study Details
Study Description
Brief Summary
The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
Phase 4 |
Detailed Description
The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration. The effects of dexmedetomidine have only been compared at lower doses. This trial examined the effect of greater dose of dexmedetomidine on thoracic paravertebral block analgesia duration.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: dexmedetomidine group a combination of ropivacaine and dexmedetomidine |
Drug: Dexmedetomidine
combination of ropivacaine and dexmedetomidine 20 ug every time
|
Outcome Measures
Primary Outcome Measures
- Change of analgesia duration [Change from Baseline to 3 days after surgery]
Change of thoracic paravertebral block analgesia duration
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Patients were included in the study if they were ethnic Chinese,
-
American Society of Anesthesiologists (ASA) physical status I or II,
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candidates for general anesthesia undergoing thoracic surgery
Exclusion Criteria:
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Patients were excluded if they do not want to cooperate with the test,
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had a history of radial artery puncture or coronary artery bypass grafting,
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had acute vessel trauma,or had been diagnosed with Raynaud' disease,
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had suffered from mental or neurological disorders
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | the First Hospital of China Medical University | Shenyang | Liaoning | China | 110001 |
Sponsors and Collaborators
- China Medical University, China
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 201707158