Thyroid Autoimmunity and Reproductive Failure in Danish Women

Sponsor

Rigshospitalet, Denmark (Other)

Overall Status

Unknown status

CT.gov ID

NCT02912442

Collaborator

(none)

1,200

Enrollment

Location

Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The present Ph.D.-study investigates the mechanisms behind the association between thyroid autoimmunity and reproductive failure.

Condition or Disease	Intervention/Treatment	Phase
Thyroid Infertility Autoantibodies Autoimmunity Pregnancy Loss

Study Design

Study Type:

Observational

Anticipated Enrollment :

1200 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Thyroid Autoimmunity and Reproductive Failure - a Study of Autoimmunity in Association With Treatment Outcome in Infertile Danish Women With Infertility or Recurrent Miscarriages.

Study Start Date :

Dec 1, 2016

Anticipated Primary Completion Date :

Dec 1, 2019

Anticipated Study Completion Date :

Dec 1, 2020

Arms and Interventions

Arm	Intervention/Treatment
Infertile women study 1
Infertile women study 2
Repeated pregnancy loss

Outcome Measures

Primary Outcome Measures

Live birth [2011-2015]

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

Female

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Women followed in the Fertility Clinic

Exclusion Criteria:

Pregnancy at time of blood sampling. Immune-suppressive ⁄modulatory treatments. Women referred for oocyt donation, genetic testing, and hepatitis and HIV-positivity