Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack

Sponsor

University of California, San Diego (Other)

Overall Status

Withdrawn

CT.gov ID

NCT00363753

Collaborator

(none)

Enrollment

Locations

Duration (Months)

Patients Per Site

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Pilot study of continuing aspirin versus switching to clopidogrel after stroke or transient ischemic attack.

Condition or Disease	Intervention/Treatment	Phase
Transient Ischemic Attack Stroke Aspirin Clopidogrel	Drug: aspirin versus clopidogrel	Phase 1

Detailed Description

Pilot study of continuing aspirin versus switching to clopidogrel after stroke or transient ischemic attack.

Study Design

Study Type:

Interventional

Actual Enrollment :

0 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

None (Open Label)

Primary Purpose:

Prevention

Official Title:

Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack

Study Start Date :

Aug 1, 2006

Anticipated Study Completion Date :

Mar 1, 2007

Outcome Measures

Primary Outcome Measures

mRS at three months. []

Secondary Outcome Measures

Incidence of stroke at three months, bleeding events. []

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Age 18 and older.
Stroke or transient ischemic attack (TIA) while taking aspirin within one week of consent.
Women of child-bearing potential will be included only if there is a negative pregnancy test and they agree to birth control during the treatment period.

Exclusion Criteria:

Any medical indication for a specific antiplatelet agent (aspirin, clopidogrel, ticlopidine, aggrenox), or an indication for a combination of antiplatelet agents.
Any medical indication for anticoagulation, except subcutaneous heparin for deep vein thrombosis prophylaxis.
Allergy to aspirin or clopidogrel.