Very Advanced Maternal Aged Pregnants and Early Adolescent Pregnant Women
Study Details
Study Description
Brief Summary
Maternal age is an important factor affecting the pregnancy process and its results. Adverse obstetric outcomes such as preterm birth, stillbirth, and infant mortality are more common in women older than 35 years and younger than 20 years compared to women aged 20-29. Adolescent pregnancies have been associated with an increased risk of adverse pregnancy outcomes such as preterm birth, low birth weight, perinatal death, and maternal mortality.
Advanced maternal age pregnancies were associated with higher rates of maternal hypertension and diabetes, and progressively worsening perinatal outcomes such as stillbirth, preterm birth, and low birth weight.
Although the investigators' region has high birth rates, as far as they have observed, the rates of early and advanced maternal age are also quite high. the investigators' aim in this study is to determine the absolute effects of early and advanced maternal age on pregnancy and to investigate the pregnancy outcomes of these mothers.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
The investigators' aim in this study is to determine the absolute effects of early and advanced maternal age on pregnancy and to investigate the pregnancy outcomes of these mothers. For this purpose, the information of 90 pregnant women followed in Siirt Training and Research Hospital between 2017-2021 will be accessed through the hospital's data system. Maternal age, pregnancy history, Assisted reproductive technologies history, laboratory findings, screening test results, mode of delivery, baby birth information, pregnancy complications and complications during delivery will be recorded. In the light of the information gathered, the rates of negative effects of gestational age on pregnancy will be calculated.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Early Adolescent Pregnant Women (n:80) Perinatal and neonatal results of adolescent pregnancies of 16 years and below |
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Very Advanced Maternal Aged Pregnants (n:67) Perinatal and neonatal results of pregnancies 45 years and older |
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Reproductive period Control Group (n:150) Reproductive period Pregnant Between 25-35 years |
Outcome Measures
Primary Outcome Measures
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
The % of delivery type (vaginal delivery/ cesarean section) will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of abortion will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of neonatal death will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of premature rupture of membranes (PROM) will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of preterm labor will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of ablatio placentae will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of fetal distress will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of intrauterine death will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of gestational diabetes mellitus (GDM) will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of preeclampsia will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of surmaturation will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of polyhydramnios will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of oligohydramnios will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of presentation anomaly will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of multiple pregnancy will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of intrauterine growth retardation (IUGR) will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of postpartum hemorrhage will be compared between the three groups
- The maternal and perinatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [1 month]
Rate and % of placenta previa will be compared between the three groups
- The neonatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [at the time of birth]
The fetal weight (in grams) will be compared between the three groups
- The neonatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [at the time of birth]
% of male, female gender will be compared between the three groups
- The neonatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [at the time of birth]
APGAR scores in the 1st minute (by numbers) will be compared between the three groups
- The neonatal outcomes of pregnancies of pregnant women under the age of 16 ( group 1), over the age of 45 (group 2) and between the age of 25-35 (group 3). [at the time of birth]
APGAR scores in the 5th minute (by numbers) will be compared between the three groups
Eligibility Criteria
Criteria
Inclusion Criteria:
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Pregnants under the age of 16 and younger
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pregnants over the age of 45 and older
Exclusion Criteria:
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history of chronic hypertension
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history of pre gestational diabetes
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history of chronic diseases
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excessive consumption of alcohol
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smoking pregnants
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kidney disorders
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Siirt University
Investigators
- Study Director: Şerif Aksin, Assoc.Prof, Siirt University Medical Faculty Obstetrics and Gynecology Departmant
Study Documents (Full-Text)
None provided.More Information
Publications
- Brown W, Ahmed S, Roche N, Sonneveldt E, Darmstadt GL. Impact of family planning programs in reducing high-risk births due to younger and older maternal age, short birth intervals, and high parity. Semin Perinatol. 2015 Aug;39(5):338-44. doi: 10.1053/j.semperi.2015.06.006. Epub 2015 Jul 10. Review.
- Malabarey OT, Balayla J, Klam SL, Shrim A, Abenhaim HA. Pregnancies in young adolescent mothers: a population-based study on 37 million births. J Pediatr Adolesc Gynecol. 2012 Apr;25(2):98-102. doi: 10.1016/j.jpag.2011.09.004. Epub 2011 Nov 16.
- Traisrisilp K, Tongsong T. Pregnancy outcomes of mothers with very advanced maternal age (40 years or more). J Med Assoc Thai. 2015 Feb;98(2):117-22.
- SiirtUNIVER