Visual Motor Coordination

Sponsor
National Eye Institute (NEI) (NIH)
Overall Status
Recruiting
CT.gov ID
NCT00568243
Collaborator
(none)
100
Enrollment
1
Location

Study Details

Study Description

Brief Summary

Background:
  • The relation between eye movement and brain function is a subject of interest to the National Eye Institute.

  • By comparing eye movement in healthy volunteers to research conducted on patients who have difficulty moving their eyes, the National Eye Institute hopes to develop and improve diagnostic procedures for people with eye diseases.

Objectives:

-The purpose of this study is to understand how we see visual patterns and how we move our eyes to see.

Eligibility:
  • Normal volunteers:

  • must have no serious illnesses and must be 18 years of age or older

  • who are 18 years of age or older must be willing to wear contact lenses that record eye movement.

  • individuals with a history of eye or brain diseases, or previous eye or eye muscle surgery, are not allowed to participate in this study. Individuals who are currently using eye medications also are not eligible for the study.

  • Patients:

  • who are 18 years of age or older must be willing to wear contact lenses that record eye movement.

Design:
  • Participants will visit the National Eye Institute outpatient clinic for examination and testing.

  • Participants will be screened with a medical history and eye examination (including eye pressure and eye movement tests).

  • Participants with healthy eyes will participate in eye movement testing experiments:

  • One or more sessions lasting less than three hours each.

  • Eye movements will be recorded with either a special contact lens or a video/infrared camera system.

  • For the majority of the studies done under this protocol, only one or two sessions will be required. A few studies recording very small eye movements will require three or more sessions.

Condition or DiseaseIntervention/TreatmentPhase

    Detailed Description

    This natural history study will investigate eye movements and other responses to visual stimuli in normal individuals (normal volunteers) and patients. This protocol replaces a similar protocol (80-EI-0093) which served the same purpose. Normal adult volunteers will be recruited and will undergo an eye exam to assure that there are no visual system problems. Volunteers will be studied in one or more sessions where eye movement, verbal or hand movement responses are recorded in response to visual stimuli. Patients with diseases affecting the oculomotor or visual systems will also be recruited to help us better understand these systems and to help characterize their specific disease.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    100 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Prospective
    Official Title:
    Visual Motor Coordination
    Actual Study Start Date :
    Dec 4, 2007

    Arms and Interventions

    ArmIntervention/Treatment
    1

    normal adult volunteers and patients with eye movement problems

    Outcome Measures

    Primary Outcome Measures

    1. Eye movement/responses to visual stimuli [one to many times depending if normal volunteer or patient and the number of trials required to achieve clean data for small eyemovements.]

      Analysis of eye movements to characterize basic processes (normalvolunteers) and to judge disease progress (in patients)

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    • INCLUSION CRITERIA - NORMAL VOLUNTEERS:

    • Participant must be a volunteer with no ocular, visual, or oculomotor problems.

    • Participant must be 18 years old or older.

    • Participant must be able to follow directions and actively pay attention to visual stimuli and respond as appropriate.

    • For studies which use the contact lens, participant must be able to tolerate a contact lens in either one or both eyes.

    EXCLUSION CRITERIA - NORMAL VOLUNTEERS:
    • Participant has a history of ocular or visual diseases or diseases affecting the nervous system (including myasthenia, MS, etc.) or any diseases which might affect control of eye movements or affect vision.

    • Participant has had prior eye or eye muscle surgery.

    • Participant has a history of eye patching (amblyopia or lazy eye).

    • Participant currently uses eye drops or ocular medications.

    INCLUSION CRITERIA FOR PATIENTS:
    • Participant must be18 years old or older.

    • Participant must be able to follow directions and actively pay attention to visual stimuli and respond as appropriate.

    • For studies which use the contact lens, participant must be able to tolerate a contact lens in either one or both eyes.

    EXCLUSION CRITERIA FOR PATIENTS:

    -Patient is unable to cooperate with testing, including sitting still while eye movements are recorded.

    Contacts and Locations

    Locations

    SiteCityStateCountryPostal Code
    1National Institutes of Health Clinical Center, 9000 Rockville PikeBethesdaMarylandUnited States20892

    Sponsors and Collaborators

    • National Eye Institute (NEI)

    Investigators

    • Principal Investigator: Edmond J FitzGibbon, M.D., National Eye Institute (NEI)

    Study Documents (Full-Text)

    None provided.

    More Information

    Additional Information:

    Publications

    None provided.
    Responsible Party:
    National Eye Institute (NEI)
    ClinicalTrials.gov Identifier:
    NCT00568243
    Other Study ID Numbers:
    • 080031
    • 08-EI-0031
    First Posted:
    Dec 5, 2007
    Last Update Posted:
    Apr 8, 2022
    Last Verified:
    Jun 4, 2021

    Study Results

    No Results Posted as of Apr 8, 2022