Non Small Cell Lung Cancer Clinical Trials

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
N
Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for, Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas
Recruiting
  • Carcinoma, Non-Small-Cell Lung
  • +4 more
  • Decitabine (DAC)
  • +2 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
2022-04-07
Apr 7, 2022
A
A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line Treatment
Recruiting
  • Non-small Cell Lung Cancer
  • Birmingham, Alabama
  • +45 more
2022-04-06
Apr 6, 2022
M
Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86)
Recruiting
  • Non-Small Cell Lung Cancer
  • Pembrolizumab SC
  • +6 more
  • Jonesboro, Arkansas
  • +103 more
2022-04-07
Apr 7, 2022
N
Non-Viral TCR Gene Therapy
Recruiting
  • Endocrine/Neuroendocrine
  • +4 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
2022-04-07
Apr 7, 2022
L
A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer
Recruiting
  • Non-Small Cell Lung Cancer
  • Berazategui, Buenos Aires, Argentina
  • +206 more
2022-04-06
Apr 6, 2022
S
Neoadjuvant of Sintilimab Combined With Chemotherapy for Resectable NSCLC（neoSCORE）
Active, not recruiting
  • Non-small Cell Lung Cancer
  • sintilimab
  • +3 more
  • Hangzhou, Zhejiang, China
    Second Affiliated Hospital, School of Medicine, Zhejiang Univers
2022-04-06
Apr 6, 2022
C
Study of Molecular Response Adaptive Immuno-Chemotherapy in Patients With NSCLC
Active, not recruiting
  • Non-Small Cell Lung Cancer
  • Baltimore, Maryland
  • +5 more
2022-04-07
Apr 7, 2022
H
A Study to Evaluate Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
Recruiting
  • Non-Small Cell Lung Cancer
  • La Jolla, California
  • +181 more
2022-04-07
Apr 7, 2022
N
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Recruiting
  • Endocrine Tumors
  • +5 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
2022-04-07
Apr 7, 2022
M
ALT-803 Plus Nivolumab in Patients With Pretreated, Advanced or Metastatic Non-Small Cell Lung Cancer
Active, not recruiting
  • Non-small Cell Lung Cancer
  • ALT-803
  • Nivolumab
  • Weston, Florida
  • +3 more
2022-03-30
Mar 30, 2022
T
Tempus NSCLC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With NSCLC Using NGS Assays
Not yet recruiting
  • Non-Small Cell Lung Cancer
  • Observation
  • (no location specified)
2022-04-07
Apr 7, 2022
M
Efficacy and Safety Study of Stereotactic Body Radiotherapy (SBRT) With or Without Pembrolizumab (MK-3475) in Adults With Unresected Stage I or II Non-Small Cell Lung Cancer (NSCLC) (MK-3475-867/KEYNOTE-867)
Recruiting
  • Non-Small Cell Lung Cancer
  • Stereotactic Body Radiotherapy (SBRT)
  • +2 more
  • Birmingham, Alabama
  • +169 more
2022-04-07
Apr 7, 2022
D
Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)
Active, not recruiting
  • Non-small Cell Lung Cancer
  • Phoenix, Arizona
  • +81 more
2022-04-07
Apr 7, 2022
L
A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)
Recruiting
  • Non-Small Cell Lung Cancer
  • +3 more
  • Scottsdale, Arizona
  • +84 more
2022-04-06
Apr 6, 2022
L
Assessing the Efficacy and Safety of Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non-Small Cell Lung Cancer Receiving Definitive Chemoradiotherapy
Recruiting
  • Non-Small Cell Lung Cancer
  • Chemoradiotherapy
  • Chemoradiotherapy with Integrated Boost Dose
  • London, Ontario, Canada
  • +6 more
2022-04-07
Apr 7, 2022
N
Biospecimen Procurement for Genitourinary Malignancies Branch Immunotherapy Protocols
Recruiting
  • Multiple Myeloma
  • +4 more
    • Bethesda, Maryland
      National Institutes of Health Clinical Center, 9000 Rockville Pi
    2022-04-07
    Apr 7, 2022
    N
    Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors
    Recruiting
    • Non-Small Cell Lung Cancer
    • +4 more
      • Bethesda, Maryland
        National Institutes of Health Clinical Center, 9000 Rockville Pi
      2022-04-07
      Apr 7, 2022
      N
      Harvesting Cells for Experimental Cancer Treatments
      Enrolling by invitation
      • Melanoma
      • +4 more
        • Bethesda, Maryland
          National Institutes of Health Clinical Center, 9000 Rockville Pi
        2022-04-07
        Apr 7, 2022
        E
        A Study of LY3023414 in Participants With Advanced Cancer - 2022
        Completed
        • Advanced Cancer
        • +5 more
        • Los Angeles, California
        • +7 more
        2022-04-07
        Apr 7, 2022
        A
        A Study to Evaluate Subcutaneous Durvalumab in Patients With Non-Small Cell Lung Cancer and Small Cell Lung Cancer
        Recruiting
        • Non-Small Cell Lung Cancer
        • Small Cell Lung Cancer
        • Tucson, Arizona
        • +18 more
        2022-04-06
        Apr 6, 2022
        W
        Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer
        Not yet recruiting
        • Non Small Cell Lung Cancer
        • Non-small Cell Lung Cancer
          • Atlanta, Georgia
          • +6 more
          2022-03-29
          Mar 29, 2022
          B
          A Study to Test Different Doses of BI 1810631 in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
          Recruiting
          • Neoplasm Metastasis
          • Non-Small Cell Lung Cancer
          • BI 1810631
          • Dallas, Texas
          • +4 more
          2022-04-06
          Apr 6, 2022
          C
          A Phase I Study of TQ-B3456 on Tolerance and Pharmacokinetics - 2022
          Terminated
          • Non-small Cell Lung Cancer
          • Shanghai, Shanghai, China
            No. 241 Huaihai West Road, Xuhui District, Shanghai
          2022-03-29
          Mar 29, 2022
          N
          Study of NGM831 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors
          Recruiting
          • Pancreatic Cancer
          • +15 more
          • Grand Rapids, Michigan
          • +2 more
          2022-04-05
          Apr 5, 2022
          M
          Tarlox and Sotorasib in Patients With KRAS G12C Mutations
          Recruiting
          • Non-Small Cell Lung Cancer
          • Sotorasib and Tarloxotinib
          • Charleston, South Carolina
            Hollings Cancer Center at Medical University of South Carolina
          2022-03-28
          Mar 28, 2022