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pevonedistat

Pevonedistat is a drug used to treat Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Recurrent Acute Myeloid Leukemia, and other conditions. Pevonedistat is being actively studied in 19 studies and prior, has been studied in 5.

Top SponsorsTop SitesTop Investigators
National Cancer Institute (NCI)Moffitt Cancer CenterEhab L Atallah
TakedaUniversity of North Carolina at Chapel HillJulio Barredo, MD
Millennium Pharmaceuticals, Inc.Azienda Ospedaliera Universitaria CareggiJustin Watts, MD
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
W
Terminated
  • Myelofibroses
  • Pevonedistat
  • +3 more
  • Saint Louis, Missouri
    Washington University School of Medicine
2021-12-16
Dec 16, 2021
T
Withdrawn
  • Myelodysplastic Syndromes (MDS)
  • Pevonedistat
  • +2 more
  • (no location specified)
2021-09-23
Sep 23, 2021
T
No longer available
  • Myelodysplastic Syndromes
  • (no location specified)
2021-09-08
Sep 8, 2021
U
Terminated
  • Non-small Cell Lung Cancer
  • Ann Arbor, Michigan
    University of Michigan Comprehensive Cancer Center
2021-12-16
Dec 16, 2021
M
Active, not recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • +2 more
  • Pembrolizumab
  • Pevonedistat
  • Houston, Texas
    M D Anderson Cancer Center
2022-01-18
Jan 18, 2022
C
Active, not recruiting
  • Acute Myeloid Leukemia
  • +5 more
  • Duarte, California
    City of Hope Medical Center
2022-02-17
Feb 17, 2022
J
Active, not recruiting
  • Refractory Acute Lymphoblastic Leukemia
  • Relapsed Acute Lymphoblastic Leukemia
  • Pevonedistat
  • +7 more
  • Miami, Florida
    University of Miami
2021-11-02
Nov 2, 2021
M
Active, not recruiting
  • Mesothelioma
  • pevonedistat
  • Pemetrexed and cisplatin
  • Basking Ridge, New Jersey
  • +7 more
2021-09-10
Sep 10, 2021
J
Completed
  • Acute Myelogenous Leukemia
  • +3 more
  • Miami, Florida
    University of Miami
2021-12-07
Dec 7, 2021
M
Completed
  • Advanced Solid Neoplasm
  • Pevonedistat
  • +3 more
  • Santa Monica, California
  • +7 more
2021-06-22
Jun 22, 2021
T
Active, not recruiting
  • Myelodysplastic Syndromes
  • +5 more
  • New York, New York
  • +7 more
2022-02-07
Feb 7, 2022
M
Completed
  • Advanced Solid Neoplasm
  • Pevonedistat
  • +4 more
  • Atlanta, Georgia
  • +3 more
2021-03-08
Mar 8, 2021
M
Terminated
  • Acute Myeloid Leukemia (AML)
  • Pevonedistat
  • +2 more
  • Hershey, Pennsylvania
    Penn State Hershey Medical Center: Penn State Cancer Institute
2020-11-22
Nov 22, 2020
N
Active, not recruiting
  • Recurrent Acute Myeloid Leukemia
  • Refractory Acute Myeloid Leukemia
  • Los Angeles, California
  • +3 more
2022-03-25
Mar 25, 2022
C
Recruiting
  • B-Cell Prolymphocytic Leukemia
  • +17 more
  • Buffalo, New York
  • +1 more
2021-07-04
Jul 4, 2021
N
Recruiting
  • Recurrent Acute Myeloid Leukemia
  • +3 more
  • Tampa, Florida
  • +5 more
2021-11-17
Nov 17, 2021
N
Active, not recruiting
  • Recurrent Plasma Cell Myeloma
  • Refractory Plasma Cell Myeloma
  • Ixazomib Citrate
  • Pevonedistat
  • New Haven, Connecticut
  • +8 more
2022-03-29
Mar 29, 2022
M
Recruiting
  • Acute Myeloid Leukemia
  • +15 more
  • Houston, Texas
    M D Anderson Cancer Center
2021-03-09
Mar 9, 2021
U
Recruiting
  • Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
  • +2 more
  • Tucson, Arizona
  • +2 more
2021-10-14
Oct 14, 2021
U
Active, not recruiting
  • Acute Myeloid Leukemia in Remission
  • +2 more
  • Aachen, Germany
  • +13 more
2022-01-21
Jan 21, 2022
M
Active, not recruiting
  • Acute Myelogenous Leukemia
  • Rochester, Minnesota
  • +1 more
2021-09-21
Sep 21, 2021
C
Active, not recruiting
  • Recurrent Lymphoma
  • +5 more
  • Birmingham, Alabama
  • +19 more
2022-03-23
Mar 23, 2022
N
Active, not recruiting
  • Metastatic Lung Non-Small Cell Squamous Carcinoma
  • +7 more
  • Los Angeles, California
  • +9 more
2022-03-01
Mar 1, 2022