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RNAi

Showing 51 - 71 of 71

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

TTR-mediated Amyloidosis Trial in United Kingdom, United States (ALN-TTRSC (revusiran) for subcutaneous administration)

Completed
  • TTR-mediated Amyloidosis
  • ALN-TTRSC (revusiran) for subcutaneous administration
  • Boston, Massachusetts
  • +3 more
Jan 26, 2018

Atherosclerotic Cardiovascular Disease, Familial Hypercholesterolemia, Diabetes Trial in Worldwide (ALN-PCSSC, Normal Saline)

Completed
  • Atherosclerotic Cardiovascular Disease
  • +2 more
  • Jacksonville, Florida
  • +53 more
Apr 23, 2019

TTR-mediated Amyloidosis, Amyloidosis, Hereditary, Amyloid Neuropathies, Familial Trial in Worldwide (patisiran (ALN-TTR02),

Completed
  • TTR-mediated Amyloidosis
  • +5 more
  • patisiran (ALN-TTR02)
  • Sterile Normal Saline (0.9% NaCl)
  • La Mesa, California
  • +51 more
Nov 18, 2018

TTR-mediated Amyloidosis Trial in Worldwide (Patisiran)

Completed
  • TTR-mediated Amyloidosis
  • Boston, Massachusetts
  • +9 more
Oct 23, 2018

Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC), Amyloidosis, Hereditary, Amyloid Neuropathies, Familial

Completed
  • Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)
  • +5 more
  • Revusiran (ALN-TTRSC)
  • Sterile Normal Saline (0.9% NaCl)
  • Bakersfield, California
  • +60 more
Jun 22, 2018

Occult Cardiac Amyloid in the Elderly With Aortic Stenosis.

Unknown status
  • Cardiac Amyloidosis
  • Aortic Stenosis
  • Baseline assessment
  • +6 more
  • London, United Kingdom
  • +1 more
Apr 17, 2018

Alpha-1 Antitrypsin Deficiency Trial in Worldwide (ARC-AAT Injection)

Withdrawn
  • Alpha-1 Antitrypsin Deficiency
  • ARC-AAT Injection
  • Toronto, Ontario, Canada
  • +3 more
May 17, 2017

Hepatitis C Trial in United States (TT-034)

Completed
  • Hepatitis C
  • San Diego, California
  • +3 more
Nov 28, 2016

TTR-mediated Amyloidosis Trial in Leeds, London (ALN-TTRSC (revusiran), Sterile Normal Saline (0.9% NaCl))

Completed
  • TTR-mediated Amyloidosis
  • ALN-TTRSC (revusiran)
  • Sterile Normal Saline (0.9% NaCl)
  • Leeds, United Kingdom
  • +1 more
Feb 4, 2016

Hypercholesterolemia Trial in Leeds, London (ALN-PCSSC, Sterile Normal Saline (0.9% NaCl))

Completed
  • Hypercholesterolemia
  • Leeds, United Kingdom
  • +1 more
Dec 16, 2015

Identifying Early Lung Cancer Cells in Malignant Pleural

Withdrawn
  • Lung Cancer
  • Metastatic Cancer
  • microarray analysis
  • +3 more
  • Cleveland, Ohio
    Case Medical Center, University Hospitals Seidman Cancer Center,
Oct 8, 2015

Chronic Hepatitis B Trial in Melbourne (ARC-520 Injection)

Withdrawn
  • Chronic Hepatitis B
  • ARC-520 Injection
  • Melbourne, Victoria, Australia
    Nucleus Network Ltd
Aug 12, 2015

Ocular Pain, Dry Eye Syndrome Trial in Madrid, Oviedo (SYL1001, Placebo)

Completed
  • Ocular Pain
  • Dry Eye Syndrome
  • Madrid, Spain
  • +2 more
May 22, 2015

Transthyretin (TTR)-Mediated Amyloidosis Trial in London (patisiran (ALN-TTR02), Sterile Normal Saline (0.9% NaCl))

Completed
  • Transthyretin (TTR)-Mediated Amyloidosis
  • patisiran (ALN-TTR02)
  • Sterile Normal Saline (0.9% NaCl)
  • London, United Kingdom
    Clinical Site
May 22, 2015

Cancer, Solid Tumor Trial in Duarte, Los Angeles, San Antonio (CALAA-01)

Terminated
  • Cancer
  • Solid Tumor
  • Duarte, California
  • +2 more
Oct 30, 2013

Ocular Hypertension, Open Angle Glaucoma Trial in Estonia, Germany, Spain (SYL040012, Placebo)

Completed
  • Ocular Hypertension
  • Open Angle Glaucoma
  • Tallin, Estonia
  • +10 more
Jun 7, 2013

Glaucoma, Ocular Hypertension Trial in Pamplona, Madrid (SYL040012)

Completed
  • Glaucoma
  • Ocular Hypertension
  • Pamplona, Navarra, Spain
  • +1 more
Sep 26, 2012

HIV-1 Infection Trial in Duarte (pHIV7-shI-TAR-CCR5RZ treated CD4 cells)

Terminated
  • HIV-1 Infection
  • pHIV7-shI-TAR-CCR5RZ treated CD4 cells
  • Duarte, California
    Beckman Research Institute of City of Hope
Jan 18, 2011

Solid Tumors Trial in Spain, United States (ALN-VSP02)

Completed
  • Solid Tumors
  • Scottsdale, Arizona
  • +9 more
Aug 23, 2011

HIV Infection Trial in United States (VRX496-Modified Autologous T cells)

Active, not recruiting
  • HIV Infection
  • VRX496-Modified Autologous T cells
  • Palo Alto, California
  • +4 more
Jun 7, 2011

Liver Tissue and Blood From Individuals With Chronic Viral

Unknown status
  • Hepatitis C
  • +4 more
    • Toronto, Ontario, Canada
      Liver Clinic, Toronto Western Hospital, UHN
    Nov 29, 2005