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41BB

Showing 1 - 25 of 817
STUDY
CONDITIONS
INTERVENTIONS
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LAST UPDATED

Malignant Brain Tumor, Recurrent Malignant Brain Tumor, Refractory Malignant Brain Tumor Trial in Duarte (Cyclophosphamide,

Recruiting
  • Malignant Brain Neoplasm
  • +2 more
  • Duarte, California
    City of Hope Medical Center
May 19, 2022

B Cell Leukemias, B Cell Lymphomas Trial in Philadelphia (CART22 cells transduced with a lentiviral vector to express anti-CD22

Recruiting
  • B Cell Leukemias
  • B Cell Lymphomas
  • CART22 cells transduced with a lentiviral vector to express anti-CD22 scFv TCRz:41BB
  • Philadelphia, Pennsylvania
    Children's Hospital of Philadelphia
Jan 19, 2022

Ependymoma, Glioblastoma, Medulloblastoma Trial in Duarte (IL13Ralpha2-specific Hinge-optimized 41BB-co-stimulatory CAR

Recruiting
  • Ependymoma
  • +3 more
  • IL13Ralpha2-specific Hinge-optimized 41BB-co-stimulatory CAR Truncated CD19-expressing Autologous T-Lymphocytes
  • Duarte, California
    City of Hope Medical Center
Mar 9, 2022

Metastatic Solid Tumors, NSCLC, Melanoma Trial in United States (INBRX-105 - PDL1x41BB antibody, Pembrolizumab)

Recruiting
  • Metastatic Solid Tumors
  • +7 more
  • Scottsdale, Arizona
  • +12 more
Jan 26, 2023

Glioblastoma, Glioblastoma Multiforme, Glioma, Malignant Trial in Jyväskylä, Oulu, New Delhi (EGFRvIII-specific hinge-optimized

Active, not recruiting
  • Glioblastoma
  • +2 more
  • EGFRvIII-specific hinge-optimized CD3 ζ-stimulatory/41BB-co-stimulatory Chimeric Antigen Receptor autologous T-lymphocytes
  • Jyväskylä, Finland
  • +2 more
Sep 30, 2021

HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2-positive Bladder Cancer Trial in United States (PRS-343)

Completed
  • HER2-positive Breast Cancer
  • +3 more
  • Tucson, Arizona
  • +9 more
Jan 18, 2022

Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma Trial in Duarte (CS1-CAR T Therapy, Cyclophosphamide, Fludarabine)

Recruiting
  • Recurrent Plasma Cell Myeloma
  • Refractory Plasma Cell Myeloma
  • CS1-CAR T Therapy
  • +3 more
  • Duarte, California
    City of Hope Medical Center
Nov 15, 2021

Hepatitis B Trial in Worldwide (JNJ-73763989, JNJ-56136379, Entecavir (ETV))

Active, not recruiting
  • Hepatitis B
  • Baltimore, Maryland
  • +9 more
Jan 17, 2023

Lymphoma Trial in United States (ACTR087, rituximab)

Completed
  • Lymphoma
  • ACTR087
  • rituximab
  • Gilbert, Arizona
  • +6 more
Mar 27, 2020

Multiple Sclerosis (MS) Trial in Worldwide (Nabiximols, Placebo)

Recruiting
  • Multiple Sclerosis (MS)
  • Port Charlotte, Florida
  • +27 more
Jan 27, 2022

Hepatitis B Trial in Worldwide (JNJ-56136379, Placebo, NA (ETV or TDF))

Completed
Has Results
  • Hepatitis B
  • Bakersfield, California
  • +75 more
Oct 24, 2022

Respiratory Syncytial Virus Infections Trial in Worldwide (RSVPreF3 OA investigational vaccine)

Active, not recruiting
  • Respiratory Syncytial Virus Infections
  • RSVPreF3 OA investigational vaccine
  • Mobile, Alabama
  • +45 more
Jul 22, 2022

Thoracic Tumors, NSCLC, Small Cell Lung Cancer Trial (ES101)

Withdrawn
  • Thoracic Tumors
  • +2 more
  • (no location specified)
Apr 22, 2022

Lymphoblastic Leukemia, Lymphoblastic Leukemia in Children, Lymphoblastic Leukemia, Acute Adult Trial in Singapore (Anti-CD19

Recruiting
  • Lymphoblastic Leukemia
  • +5 more
  • Anti-CD19 CAR T-cells
  • Singapore, Singapore
  • +1 more
Dec 4, 2022

CNS Tumors, Atypical Teratoid/Rhabdoid Tumor, Diffuse Midline Glioma, H3 K27M-Mutant Trial in Memphis (B7-H3-CAR T cells)

Not yet recruiting
  • Central Nervous System Neoplasms
  • +6 more
  • B7-H3-CAR T cells
  • Memphis, Tennessee
    St. Jude Children's Research Hospital
Apr 18, 2023

Pancreatic Ductal Adenocarcinoma, NSCLC, Colorectal Cancer Trial (AFNT-211)

Not yet recruiting
  • Pancreatic Ductal Adenocarcinoma
  • +4 more
  • (no location specified)
Oct 23, 2023

Chemo Resistant Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic Leukemia Trial in Philadelphia (CART22-65s cells,

Active, not recruiting
  • Chemotherapy Resistant Acute Lymphoblastic Leukemia
  • Refractory Acute Lymphoblastic Leukemia
  • CART22-65s cells
  • huCART19 Cells
  • Philadelphia, Pennsylvania
    University of Pennsylvania
Feb 18, 2022

Lymphoma, Non-Hodgkin Trial in Worldwide (RO7227166, Obinutuzumab, Glofitamab)

Recruiting
  • Lymphoma, Non-Hodgkin
  • Pasadena, California
  • +14 more
Jan 30, 2023

Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia, Non Hodgkin Lymphoma Trial (PACE CART19)

Withdrawn
  • Acute Lymphoblastic Leukemia
  • +2 more
  • PACE CART19
  • (no location specified)
Mar 9, 2022

Coronary Artery Disease Trial in United Kingdom (BioMatrix Alpha)

Not yet recruiting
  • Coronary Artery Disease
  • BioMatrix Alpha
  • Birmingham, United Kingdom
  • +5 more
Mar 23, 2023

Isotonic and Hypotonic Intravenous Maintenance Fluids In Term

Recruiting
  • Newborn Complication
  • +5 more
  • Intravenous isotonic fluid - NaCl 131-154 mmol/L in 5% dextrose
  • Intravenous Hypotonic fluid- Sodium Chloride < 130 mmol/L
  • İzmir, Turkey
    Dokuz Eylul University
Aug 1, 2022

Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL, Infants With Very High Risk KMT2A B-ALL, Patients With CNS

Active, not recruiting
  • Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL
  • +2 more
  • Murine CART19
  • Philadelphia, Pennsylvania
    Children's Hospital of Philadelphia
Jan 11, 2022

T-Cell Lymphocytic Leukemia, T-Cell Chronic Lymphocytic Leukemia, T Cell Non-Hodgkin Lymphoma Trial in Wuhan (Fludarabine +

Recruiting
  • T-Cell Lymphocytic Leukemia
  • +2 more
  • Fludarabine + Cyclophosphamide + CAR7-T Cells
  • Wuhan, Hubei, China
    Union Hospital, Huazhong University of Science and Technology
Mar 1, 2022

Diabetes, Type 2 Trial in United Kingdom (Atorvastatin and Omega-3 fatty acids)

Completed
  • Diabetes, Type 2
  • Atorvastatin and Omega-3 fatty acids
  • Irvine, Ayrshire, United Kingdom
  • +58 more
Feb 17, 2021

Solid Tumors, Tumors, Malignant Tumor Trial in Shanghai (ES101)

Recruiting
  • Solid Tumors
  • +2 more
  • Shanghai, Shanghai, China
    Shanghai East Hospital
Apr 11, 2021