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519 items
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LAST UPDATED
A
Study of ACE-536 for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS) - 2018
Completed
  • Anemia
  • ACE-536
  • Dresden, Germany
    Acceleron Investigative Site
2021-04-29
Apr 29, 2021
A
ACE-536 Extension Study - Myelodysplastic Syndromes - 2020
Completed
  • Myelodysplastic Syndromes
  • ACE-536
  • Dresden, Germany
    Acceleron Investigative Site
2021-04-29
Apr 29, 2021
A
ACE-536 Extension Study - Beta Thalassemia - 2020
Completed
  • Beta-Thalassemia
  • ACE-536
  • Athens, Greece
  • +6 more
2021-05-17
May 17, 2021
C
Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants Who Require Regular RBC Transfusions Due to Beta (β)-Thalassemia.
Recruiting
  • Beta-Thalassemia
  • ACE-536
  • Los Angeles, California
  • +7 more
2021-06-03
Jun 3, 2021
M
Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients
Recruiting
  • Myelodysplastic Syndromes
  • Miami, Florida
  • +5 more
2021-11-10
Nov 10, 2021
M
Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts
Recruiting
  • Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis
  • Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable
  • Rochester, Minnesota
    Mayo Clinic in Rochester
2022-01-19
Jan 19, 2022
C
A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia
Active, not recruiting
Has Results
  • Thalassemia
  • Los Angeles, California
  • +13 more
2021-10-18
Oct 18, 2021
C
A Study to Evaluate the Efficacy, Drug Levels and Safety of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in Chinese and Japanese Participants With Ring Sideroblasts Who Require Red Blood Cell Transfusions
Recruiting
  • Myelodysplastic Syndromes
  • Beijing, China
  • +23 more
2022-02-03
Feb 3, 2022
G
Study Evaluating Combination of Luspatercept in LR-MDS Without RS Having Failed or Being Ineligible to ESA
Not yet recruiting
  • MDS
  • Myelodysplastic Syndromes
  • Luspatercept Injection [Reblozyl]
  • Eprex
  • Amiens, France
  • +28 more
2021-12-20
Dec 20, 2021
C
A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence
Active, not recruiting
  • Primary Myelofibrosis
  • Anemia
  • Phoenix, Arizona
  • +23 more
2022-01-10
Jan 10, 2022
C
A Study of Luspatercept (ACE-536) to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes - 2020
Completed
Has Results
  • Myelodysplastic Syndromes
  • Stanford, California
  • +73 more
2021-11-19
Nov 19, 2021
C
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia - 2021
Completed
Has Results
  • Erythrocyte Transfusion
  • Beta-Thalassemia
  • Los Angeles, California
  • +72 more
2022-01-21
Jan 21, 2022
C
A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve
Recruiting
  • Myelodysplastic Syndromes
  • Birmingham, Alabama
  • +239 more
2022-03-15
Mar 15, 2022
C
A Study to Evaluate Long-term Safety in Subjects Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
Recruiting
  • Myelodysplastic Syndromes (MDS)
  • +2 more
  • Los Angeles, California
  • +121 more
2020-11-30
Nov 30, 2020
C
An Efficacy and Safety Study of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in Japanese Subjects Who Are Not Requiring Red Blood Cell Transfusion
Recruiting
  • Myelodysplastic Syndromes
  • Chiba, Japan
  • +18 more
2022-01-08
Jan 8, 2022
C
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
Recruiting
  • Myeloproliferative Disorders
  • +4 more
  • ACE-536
  • Placebo
  • La Jolla, California
  • +149 more
2022-03-18
Mar 18, 2022
T
A Study of TAK-536 in Children From 2 to Less Than 6 Years Old With High Blood Pressure
Recruiting
  • Hypertension
  • Nagoya, Aichi, Japan
  • +17 more
2021-10-14
Oct 14, 2021
A
Study to Evaluate the Effects of ACE-536 in Patients With Beta-thalassemia - 2015
Completed
  • B-Thalassemia
  • ACE-536
  • Athens, Greece
  • +7 more
2016-12-13
Dec 13, 2016
M
Sotatercept (ACE-011) With Lenalidomide or Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma
Active, not recruiting
  • Multiple Myeloma
  • Atlanta, Georgia
  • +3 more
2021-10-28
Oct 28, 2021
G
A Bioequivalence Study Between Capozide Versus ACE-Hemmer-ratiopharm in Healthy Adult Participants Under Fasting Conditions
Not yet recruiting
  • Healthy Volunteers
  • (no location specified)
2022-02-02
Feb 2, 2022
U
Impact of Angiotensin Converting Enzyme Activity on Exercise Training Sensitivity - 2019
Completed
  • Exercise
  • Angiotensin-Converting Enzyme Inhibitors
  • Copenhagen, Denmark
    Department of Nutrition, Exercise and Sports
2020-11-03
Nov 3, 2020
A
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension - 2022
Completed
  • Pulmonary Arterial Hypertension
  • Sotatercept
  • Tucson, Arizona
  • +3 more
2022-03-28
Mar 28, 2022
A
Continuing or Discontinuing ACE/ARBs in Patients With Chronic Kidney Disease Undergoing Coronary Angiography
Recruiting
  • Contrast-induced Nephropathy
  • +2 more
  • Continue ACEI or ARBs ( Enalapril , Ramipril , Valsartan , Candesartan, Losartan )
  • Hold ACEI or ARBs
  • Nablus, West Bank, Palestinian Territory, occupied
    An-Najah National University Hospital
2022-02-27
Feb 27, 2022
X
XACT ACE Observational Registry
Recruiting
  • Tumors
  • Hands-free, user-controlled robotic system intended to assist in the planning and advancement of an instrument during CT guided percutaneous procedures. T
  • Sarasota, Florida
    Sarasota Interventional Radiology
2021-10-21
Oct 21, 2021
X
Pilot Study of the ACE System in Lung Procedures - 2021
Completed
  • Lung Diseases
  • XACT ACE Robotics study arm
  • Burlington, Massachusetts
    Lahey Hospital and Medical Center
2021-08-05
Aug 5, 2021