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Allopregnanolone

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STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Depression Trial (brexanolone, )

Recruiting
  • Depression
  • Boston, Massachusetts
    Brigham and Women's Hospital
Nov 8, 2022

Alzheimer Dementia, Late Onset Alzheimer, Neurodegenerative Diseases Trial (Allopregnanolone, Placebo)

Not yet recruiting
  • Alzheimer Dementia
  • +2 more
  • Allopregnanolone
  • Placebo
  • (no location specified)
May 23, 2022

Tinnitus Trial (Brexanolone)

Not yet recruiting
  • Tinnitus
  • (no location specified)
Dec 1, 2022

Postpartum Depression Trial in United States (ZULRESSO®)

Completed
  • Postpartum Depression
  • Culver City, California
  • +5 more
Aug 2, 2022

Acute Respiratory Distress Syndrome, COVID-19 Trial in United States (Brexanolone, Placebo)

Terminated
  • Acute Respiratory Distress Syndrome
  • COVID-19
  • Fresno, California
  • +8 more
Aug 17, 2022

Pregnancy and Anxious Thoughts: The Role of Immune and Endocrine

Completed
  • Perinatal Anxiety
  • Coping with Anxiety through Living Mindfully (CALM) Pregnancy
  • Baltimore, Maryland
    Women's Mood Disorders Center
Jan 9, 2023

Methamphetamine-dependence, Postpartum Abstinence Trial in Salt Lake City (Progesterone, Placebo)

Recruiting
  • Methamphetamine-dependence
  • Postpartum Abstinence
  • Salt Lake City, Utah
    University of Utah
Apr 15, 2022

Mild Cognitive Impairment, Alzheimer Trial in Los Angeles (Allopregnanolone injection (intravenous solution), Placebo injection

Completed
  • Mild Cognitive Impairment
  • Alzheimer Disease
  • Allopregnanolone injection (intravenous solution)
  • Placebo injection (intravenous solution)
  • Los Angeles, California
    University of Southern California - Alzheimer Disease Research C
Jul 2, 2019

Anxiety Trial in Rawalpindi (Cognitive Behavioral Therapy (CBT) for anxiety during pregnancy)

Completed
  • Anxiety
  • Cognitive Behavioral Therapy (CBT) for anxiety during pregnancy
  • Rawalpindi, Pakistan
    Holy Family Hospital
Oct 18, 2022

Premenstrual Syndrome, PMS, Healthy Trial run by the NIMH (Dutasteride, Placebo oral capsule)

Completed
  • Premenstrual Syndrome
  • +3 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
Dec 14, 2019

Chronic Low Back Pain Trial in Durham (Pregnenolone, DHEA, Placebo)

Not yet recruiting
  • Chronic Low Back Pain
  • Durham, North Carolina
    Durham VA Medical Center, Durham, NC
Jul 11, 2023

Healthy Volunteers Trial in Adelaide (LYT-300, Placebo)

Recruiting
  • Healthy Volunteers
  • Adelaide, South Australia, Australia
    CMAX
Dec 13, 2021

Tourette Syndrome in Children Trial in Salt Lake City (Tic suppression task)

Not yet recruiting
  • Tourette Syndrome in Children
  • Tic suppression task
  • Salt Lake City, Utah
    University of Utah
Mar 14, 2022

MDD Trial in Boston (Ganaxolone)

Completed
  • Major Depressive Disorder
  • Boston, Massachusetts
    Massachusetts General Hospital
Feb 13, 2019

Fragile X-associated Tremor/Ataxia Syndrome Trial in Sacramento (Allopregnanolone)

Completed
  • Fragile X-associated Tremor/Ataxia Syndrome
  • Allopregnanolone
  • Sacramento, California
    UC Davis MIND Institute
Nov 13, 2018

PMDD, Stress, Mood Trial in Philadelphia (Sertraline)

Completed
  • PMDD
  • +2 more
  • Baltimore, Maryland
    Center for Women's Reproductive Mental Health, Johns Hopkins Uni
Oct 25, 2022

MDD, Postpartum Depression Trial in Copenhagen (Transdermal patch estradiol, Transdermal patch )

Recruiting
  • Major Depressive Disorder
  • Postpartum Depression
  • Transdermal patch estradiol
  • Transdermal patch placebo
  • Copenhagen, Denmark
    Neurobiology Researc hUnit
Sep 17, 2021

MDD Trial in Dallas (Pregnenolone 500 mg, Pregnenolone 800 mg, Placebo)

Completed
  • Major Depressive Disorder
  • Pregnenolone 500 mg
  • +2 more
  • Dallas, Texas
    UT Southwestern Medical Center
Aug 29, 2022

Stress, Inflammation and Neuroimaging in Major Depressive

Not yet recruiting
  • MDD
  • PMDD
    • Tübingen, Baden-Württemberg, Germany
      University Hospital Tübingen, Klinik für Psychiatrie und Psychot
    Nov 13, 2023

    Perceived Social Isolation Trial in Chicago (Pregnenolone 175mg, Pregnenolone 400mg, Placebo)

    Active, not recruiting
    • Perceived Social Isolation
    • Pregnenolone 175mg
    • +2 more
    • Chicago, Illinois
      University of Chicago
    Jan 15, 2021

    Anxiety, Depression Trial in Chicago (Healthy Mind Intervention (HMI), Healthy Body Intervention (HBI))

    Completed
    • Anxiety
    • Depression
    • Healthy Mind Intervention (HMI)
    • Healthy Body Intervention (HBI)
    • Chicago, Illinois
      Rush University Medical Center
    Jun 9, 2021

    Nicotine Dependence, Contraception Trial in Minneapolis (Low-dose Progesterone, High-dose Progesterone)

    Completed
    • Nicotine Dependence
    • Contraception
    • Low-dose Progesterone
    • High-dose Progesterone
    • Minneapolis, Minnesota
      Masonic Cancer Center, University of Minnesota
    Oct 21, 2020

    Suicidal Ideation Trial in Chicago (Estradiol Transdermal Patch 0.1 mg/24 hrs, Oral Micronized Progesterone 200mg, Inactive

    Recruiting
    • Suicidal Ideation
    • Estradiol Transdermal Patch 0.1 mg/24 hrs
    • +3 more
    • Chicago, Illinois
      University of Illinois Neuropsychiatric Institute
    Aug 17, 2022

    MDD Trial in Chengdu (HS-10353, Placebo)

    Enrolling by invitation
    • Major Depressive Disorder
    • Chengdu, Sichuan, China
      West China Hospital
    Jan 13, 2022

    Drug Effect Trial in New Haven (High Morphine Dose, Low Morphine Dose)

    Completed
    • Drug Effect
    • High Morphine Dose
    • Low Morphine Dose
    • New Haven, Connecticut
      Cosgrove Lab
    Apr 23, 2021