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U
European CML Blast Crisis Register
Recruiting
  • Chronic Myeloid Leukemia in Myeloid Blast Crisis
    • Brno, Czechia
    • +8 more
    2021-01-27
    Jan 27, 2021
    N
    An Extension Study of the Safety and Anti-leukemic Effects of Imatinib Mesylate in Participants With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Blast Crisis - 2013
    Completed
    Has Results
    • Philadelphia Chromosome Positive CML
    • imatinib mesylate
    • Chicago, Illinois
    • +9 more
    2021-06-03
    Jun 3, 2021
    D
    GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies - 2009
    Completed
    • Myelodysplastic Syndrome RAEB-I or RAEB-II
    • +2 more
    • GM-CSF secreting leukemia vaccine
    • Boston, Massachusetts
      Dana-Farber Cancer Institute
    2022-01-28
    Jan 28, 2022
    M
    ABL001 + Dasatinib + Prednisone in BCR-ABL+ B-ALL or CML
    Recruiting
    • B-cell Acute Lymphoblastic Leukemia
    • +2 more
    • Chicago, Illinois
    • +5 more
    2021-12-27
    Dec 27, 2021
    V
    PONAZA : A COMBINATION OF PONATINIB AND 5-AZACITIDINE IN CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE OR IN MYELOID BLAST CRISIS
    Recruiting
    • CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE
    • CHRONIC MYELOGENOUS LEUKAEMIA IN MYELOID BLAST CRISIS
    • Amiens, France
    • +28 more
    2020-08-06
    Aug 6, 2020
    M
    Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia Chromosome-Positive Acute Myeloid Leukemia or Myeloid Blast Phase or Accelerated Phase Chronic Myelogenous Leukemia
    Recruiting
    • Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
    • +6 more
    • Houston, Texas
      M D Anderson Cancer Center
    2022-02-25
    Feb 25, 2022
    X
    PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignancies - 2021
    Completed
    • Acute Myelogenous Leukemia
    • +3 more
    • XmAb14045
    • Jacksonville, Florida
    • +8 more
    2022-03-04
    Mar 4, 2022
    M
    Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy - 2022
    Completed
    • Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
    • +4 more
    • Eltrombopag Olamine
    • Houston, Texas
      M D Anderson Cancer Center
    2022-01-04
    Jan 4, 2022
    D
    Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and AML
    Active, not recruiting
    • Relapsed Acute Lymphoblastic Leukemia (ALL)
    • +8 more
    • San Francisco, California
    • +9 more
    2022-01-03
    Jan 3, 2022
    M
    Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CML - 2022
    Completed
    • B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
    • +6 more
    • Houston, Texas
      M D Anderson Cancer Center
    2022-03-25
    Mar 25, 2022
    U
    Decitabine With Ruxolitinib or Fedratinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms
    Recruiting
    • Acute Myeloid Leukemia
    • +8 more
    • Seattle, Washington
      Fred Hutch/University of Washington Cancer Consortium
    2022-02-25
    Feb 25, 2022
    M
    Hu8F4 in Treating Patients With Advanced Hematologic Malignancies
    Recruiting
    • Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
    • +10 more
    • Anti-PR1/HLA-A2 Monoclonal Antibody Hu8F4
    • +2 more
    • Houston, Texas
      M D Anderson Cancer Center
    2022-03-30
    Mar 30, 2022
    M
    Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers
    Recruiting
    • Acute Myeloid Leukemia
    • +6 more
    • Houston, Texas
      M D Anderson Cancer Center
    2022-01-31
    Jan 31, 2022
    A
    An Observational Registry to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With ICLUSIG® - 2019
    Terminated
    • Myeloid Leukemia, Chronic-Phase, Accelerated-Phase, Blast-Phase, Ph+ALL
      • Hackensack, New Jersey
      • +1 more
      2020-10-30
      Oct 30, 2020
      M
      Axitinib and Bosutinib in Treating Patients With Chronic, Accelerated, or Blastic Phase Chronic Myeloid Leukemia - 2019
      Terminated
      • Accelerated Phase Chronic Myelogenous Leukemia (CML)
      • +3 more
      • Houston, Texas
        M D Anderson Cancer Center
      2020-11-17
      Nov 17, 2020
      N
      Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase - 2008
      Terminated
      Has Results
      • Leukemia, Myeloid, Chronic
      • Duarte, California
      • +25 more
      2021-07-14
      Jul 14, 2021
      M
      Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia
      Recruiting
      • Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
      • +10 more
      • Houston, Texas
        M D Anderson Cancer Center
      2022-02-08
      Feb 8, 2022
      M
      Clofarabine Combinations in Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS) and Myeloid Blast Phase Chronic Myeloid Leukemia (CML) - 2013
      Completed
      Has Results
      • Acute Myeloid Leukemia
      • +2 more
      • Clofarabine 40mg/m^2
      • +5 more
      • Houston, Texas
        UT MD Anderson Cancer Center
      2020-12-03
      Dec 3, 2020
      M
      Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia
      Recruiting
      • Acute Biphenotypic Leukemia
      • +13 more
      • Houston, Texas
        M D Anderson Cancer Center
      2022-02-15
      Feb 15, 2022
      M
      Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy
      Recruiting
      • Acute Myeloid Leukemia
      • +17 more
      • Edetate Calcium Disodium
      • +2 more
      • Houston, Texas
        M D Anderson Cancer Center
      2021-07-23
      Jul 23, 2021
      M
      An Open-Label, Phase I/II Study of Two Different Schedules of Dasatinib (Sprycel) and Decitabine (Dacogen) Used in Combination for Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia (Protocol CA180357) - 2019
      Terminated
      Has Results
      • Leukemia
      • Houston, Texas
        University of Texas MD Anderson Cancer Center
      2020-09-29
      Sep 29, 2020
      U
      Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
      Recruiting
      • Hematologic Diseases
      • +11 more
      • Ann Arbor, Michigan
        University of Michigan Health System
      2021-12-02
      Dec 2, 2021
      U
      Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia - 2018
      Completed
      • Chronic Phase Chronic Myeloid Leukemia
      • +4 more
      • Toronto, Ontario, Canada
        Princess Margaret Hospital / University Health Network
      2020-10-29
      Oct 29, 2020
      N
      Nilotininb, for Patients With CML-CP, CML-AP, or CML-BC
      Available
      • Chronic Myelogenous Leukemia (CML)
      • Auchenflower, Queensland, Australia
      • +21 more
      2021-08-16
      Aug 16, 2021
      A
      Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)
      Completed
      • Chronic Myelogenous Leukemia
      • decitabine (5-aza-2'deoxycytidine)
      • Duarte, California
      • +7 more
      2020-01-13
      Jan 13, 2020