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COMT

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STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Parkinson Disease Trial in Paris (Identification of COMT HH, COMT HL or COMT LL genes, Brain MRI with resting state scan, Brain

Completed
  • Parkinson Disease
  • Identification of COMT HH, COMT HL or COMT LL genes
  • +2 more
  • Paris, France
    Groupe Hospitalier Pitié-Salpêtrière
Feb 17, 2022

Addiction Trial in Berkeley, San Francisco (Tolcapone, Placebo, Bromocriptine)

Withdrawn
  • Addiction
  • Berkeley, California
  • +1 more
Nov 12, 2021

COMT Activity and Hypnotizability

Active, not recruiting
  • Pain, Postoperative
  • Genetic Predisposition
  • Giant magnetoresistive sensor (GMR)
  • Palo Alto, California
    Stanford University/Stanford Healthcare
Aug 23, 2021

Cardiovascular Diseases Trial in Boston (Aspirin 81 mg, Placebo)

Recruiting
  • Cardiovascular Diseases
  • Aspirin 81 mg
  • Placebo
  • Boston, Massachusetts
    Brigham and Women's Hospital
Jun 23, 2021

COMT Gene Polymorphism Trial in West Haven (delta 9 tetrahydrocannabinol)

Completed
  • COMT Gene Polymorphism
  • delta 9 tetrahydrocannabinol
  • West Haven, Connecticut
    VA Connecticut Healthcare System
Feb 23, 2022

Postoperative Pain Trial in Montreal (drug, procedure, other, genetic)

Terminated
  • Postoperative Pain
  • Propranolol PO
  • +5 more
  • Montreal, Quebec, Canada
  • +1 more
Sep 24, 2021

Inhibiting COMT in Parkinson's Disease

Withdrawn
  • Parkinson's Disease
    • Zurich, ZH, Switzerland
      University Hospital Zurich, Division of Neurology
    Jan 21, 2021

    Dopaminergic Transporter Density (DAT) in Obese Women

    Recruiting
    • Obesity
    • SPECT TRODAT-1
    • Ribeirão Preto, São Paulo, Brazil
      Clinical Hospital of Ribeirão Preto Medical School
    Mar 23, 2021

    Early-onset Schizophrenia Trial in Kunming (olanzapine)

    Completed
    • Early-onset Schizophrenia
    • Kunming, Yunnan, China
      Psychiatry Department,First Affiliated Hospial Of Kunming Medica
    Feb 27, 2021

    Impulsive Behavior Trial in Berkeley, Emeryville (Tolcapone, Placebo)

    Completed
    • Impulsive Behavior
    • Berkeley, California
    • +1 more
    Nov 18, 2020

    Pathological Gambling Trial (Tolcapone, Placebo)

    Completed
    • Pathological Gambling
    • (no location specified)
    Feb 10, 2021

    Nicotine Dependence Trial in West Haven (Tolcapone, Sugar Pill)

    Completed
    • Nicotine Dependence
    • West Haven, Connecticut
      Veterans Administration Hospital
    Nov 20, 2020

    Healthy Volunteers, Modeling Psychosis Trial in Mannheim (Delta-9-tetrahydrocannabinol, Cannabidiol, Placebo)

    Unknown status
    • Healthy Volunteers
    • Modeling Psychosis
    • Mannheim, BW, Germany
      Central Institute of Mental Health
    Aug 12, 2019

    Parkinson Disease Trial in Merthyr Tydfil (50 mg BIA 9 1067, 25 mg BIA9 1067, 50 mg Ongentys)

    Completed
    • Parkinson Disease
    • 50 mg BIA 9 1067
    • +3 more
    • Merthyr Tydfil, United Kingdom
      Simbec Research Ltd
    Feb 10, 2020

    The Meaning of Dopaminergic Pathway in Sleep Breathing

    Enrolling by invitation
    • Sleep Apnea
    • Sleep-Disordered Breathing
    • Polysomnography
    • +2 more
    • Wroclaw, Poland
      Wroclaw Medical Uniwesity
    May 25, 2023

    Schizophrenia, Schizoaffective Disorder Trial run by the NIMH (Modafinil, Functional MRI, Neuropsychological Testing)

    Completed
    • Schizophrenia
    • Schizoaffective Disorder
    • Bethesda, Maryland
      National Institutes of Health Clinical Center, 9000 Rockville Pi
    Dec 6, 2019

    Blood Pressure, Low Back Pain, Hypertension Trial in Birmingham (Permanent Epidural Spinal Cord Stimulation)

    Active, not recruiting
    • Blood Pressure
    • +2 more
    • Permanent Epidural Spinal Cord Stimulation
    • Birmingham, Alabama
      University of Alabama at Birmingham
    Sep 23, 2022

    Reliability of Pupil Response to Acute Pain

    Recruiting
    • Pain
    • Osteoarthritis
      • Winston-Salem, North Carolina
        Wake Forest Baptist Medical Center
      Dec 23, 2022

      Modulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the

      Unknown status
      • Modulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT Gene
      • tdcs (sham/anodal) + drug (placebo/tyrosine)
      • Sheffield, South Yorkshire, United Kingdom
        Psychology labs
      Apr 2, 2019

      Cesarean Section Complications, Opioid Use Trial in Pittsburgh (Preoperative Genotyping)

      Recruiting
      • Cesarean Section Complications
      • Opioid Use
      • Preoperative Genotyping
      • Pittsburgh, Pennsylvania
      • +1 more
      Nov 16, 2022

      Fatigue Trial in Birmingham (Open-label intervention)

      Completed
      • Fatigue
      • Open-label placebo intervention
      • Birmingham, Alabama
        UAB Comprehensive Cancer Center
      Sep 22, 2021

      PPAP, Spine Fusion Trial in Pittsburgh (Preoperative Genotyping)

      Recruiting
      • PPAP
      • Spine Fusion
      • Preoperative Genotyping
      • Pittsburgh, Pennsylvania
      • +1 more
      Oct 7, 2022

      Rett Syndrome Trial in Australia, Canada, United Kingdom (ANAVEX2-73 oral liquid, Placebo oral liquid)

      Recruiting
      • Rett Syndrome
      • ANAVEX2-73 oral liquid
      • Placebo oral liquid
      • Sydney, New South Wales, Australia
      • +11 more
      Jan 31, 2023

      PG and PK of Oxycodone to Personalize Post-op Pain Management

      Active, not recruiting
      • Postoperative Pain
      • Opioid Dependence
      • Indianapolis, Indiana
        Riley Hospital for Children
      Nov 16, 2022

      Head Neck Cancer Trial in Houston (Computerized Tasks, Questionnaires)

      Active, not recruiting
      • Head and Neck Cancer
      • Computerized Tasks
      • Questionnaires
      • Houston, Texas
        University of Texas MD Anderson Cancer Center
      Aug 18, 2022