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Iduronidase

Showing 1 - 25 of 30
STUDY
CONDITIONS
INTERVENTIONS
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Mucopolysaccharidosis Type IH (MPS IH, Hurler Syndrome), Mucopolysaccharidosis Type IH, MPS IH, Hurler Syndrome Trial

Withdrawn
  • Mucopolysaccharidosis Type IH (MPS IH, Hurler Syndrome)
  • +2 more
  • Autologous Plasmablasts
  • (no location specified)
Oct 5, 2022

Mucopolysaccharidosis IH Trial in Milano (Frozen autologous CD34+ hematopoietic stem and progenitor cells genetically modified

Active, not recruiting
  • Mucopolysaccharidosis IH
  • Frozen autologous CD34+ hematopoietic stem and progenitor cells genetically modified with the lentiviral vector IDUA LV, encoding for the α-L-iduronidase cDNA, in their final formulation medium.
  • Milano, Italy
    Ospedale San Raffaele
Aug 6, 2021

Mucopolysaccharidosis I, Hurler's Syndrome, Hurler-Scheie Syndrome Trial in Rome (Aldurazyme (laronidase))

Recruiting
  • Mucopolysaccharidosis I
  • +3 more
  • Aldurazyme (laronidase)
  • Rome, Italy
    Dipartimento di Scienze Pediatriche Medico - Chirurgiche e Neuro
Mar 28, 2022

Mucopolysaccharidosis I, Cognitive Decline Trial in Torrance (Intrathecal recombinant human alpha iduronidase)

Terminated
  • Mucopolysaccharidosis I
  • Cognitive Decline
  • Intrathecal recombinant human alpha iduronidase
  • Torrance, California
    Los Angeles Biomedical Research Institute at Harbor-UCLA Medical
Oct 5, 2020

Mucopolysaccharidosis Type I (MPS I), Hurler Syndrome, Hurler-Scheie Syndrome Trial in Orange, Philadelphia, Porto Alegre

Active, not recruiting
  • Mucopolysaccharidosis Type I (MPS I)
  • +2 more
  • RGX-111
  • Orange, California
  • +3 more
Jan 9, 2023

MPS I Trial in Oakland (SB-318)

Terminated
Has Results
  • MPS I
  • SB-318
  • Oakland, California
    UCSF Benioff Children's Hospital Oakland
Jan 6, 2023

Mucopolysaccharidosis IH/S, Mucopolysaccharidosis IS Trial in Minneapolis (Autologous Plasmablasts (B cells))

Not yet recruiting
  • Mucopolysaccharidosis IH/S
  • Mucopolysaccharidosis IS
  • Autologous Plasmablasts (B cells)
  • Minneapolis, Minnesota
    University of Minnesota
Jan 20, 2023

MPS I, MPS1-S, MPS1-HS Trial in Porto Alegre, London, Salford (SIG-005 (hIDUA Producing Spheres))

Withdrawn
  • MPS I
  • +2 more
  • SIG-005 (hIDUA Producing Spheres)
  • Porto Alegre, Brazil
  • +2 more
Dec 16, 2022

MPS-IH (Hurler Syndrome) Trial in Worldwide (Experimental: OTL-203, Active Comparator: Allo-HSCT)

Not yet recruiting
  • MPS-IH (Hurler Syndrome)
  • Experimental: OTL-203
  • Active Comparator: Allo-HSCT
  • Oakland, California
  • +6 more
Nov 27, 2023

Mucopolysaccharidosis I Trial in Brazil, Japan, United States (JR-171)

Active, not recruiting
  • Mucopolysaccharidosis I
  • Oakland, California
  • +4 more
Aug 16, 2022

Mucopolysaccharidosis I Trial in Brazil, Japan, United States (JR-171)

Completed
  • Mucopolysaccharidosis I
  • Oakland, California
  • +5 more
Aug 16, 2022

Long Term Follow-Up for RGX-111

Enrolling by invitation
  • Mucopolysaccharidosis I
  • No Intervention
  • Orange, California
  • +2 more
Oct 25, 2023

Biomarker for Hurler Disease (BioHurler)

Active, not recruiting
  • Mucopolysaccharidosis Type I
  • +2 more
    • Cairo, Egypt
    • +4 more
    May 12, 2021

    Inherited Metabolic Disorders Who Underwent Hematopoietic Stem

    Terminated
    • Inherited Metabolic Disorders (IMD)
    • Safety and efficacy assessments
    • Minneapolis, Minnesota
      University of Minnesota
    Mar 10, 2021

    Mucopolysaccharidosis I Trial (AGT-181)

    Completed
    • Mucopolysaccharidosis I
    • (no location specified)
    Sep 21, 2018

    Mucopolysaccharidosis I Trial in Porto Alegre (AGT-181)

    Completed
    • Mucopolysaccharidosis I
    • Porto Alegre, RS, Brazil
      HCPA - Hospital das Clinicas de Porto Alegre
    Sep 16, 2018

    Hurler Syndrome Trial in Minneapolis (IRT Laronidase)

    Completed
    • Hurler Syndrome
    • IRT Laronidase
    • Minneapolis, Minnesota
      University of Minnesota, Fairview
    Nov 30, 2018

    Mucopolysaccharidosis I, Hurler Syndrome Trial in Minneapolis (Stem Cell Transplant, Laronidase ERT)

    Completed
    Has Results
    • Mucopolysaccharidosis I
    • Hurler Syndrome
    • Stem Cell Transplant
    • Laronidase ERT
    • Minneapolis, Minnesota
      Masonic Cancer Center, University of Minnesota
    Jul 10, 2019

    Mucopolysaccharidosis I Trial in Porto Alegre (AGT-181)

    Completed
    • Mucopolysaccharidosis I
    • Porto Alegre, RS, Brazil
      HCPA - Hospital das Clinicas de Porto Alegre
    Sep 16, 2018

    Brain Structure and Function in MPS Disorders

    Completed
    • Mucopolysaccharidosis Type I
    • +4 more
      • Oakland, California
      • +3 more
      Sep 4, 2019

      Mucopolysaccharidosis I Trial in United States (AGT-181 (HIRMAb-IDUA))

      Unknown status
      • Mucopolysaccharidosis I
      • AGT-181 (HIRMAb-IDUA)
      • Oakland, California
      • +5 more
      Mar 3, 2017

      Cognitive Decline, Mucopolysaccharidosis I, Hurler-Scheie Syndrome Trial in Oakland, Torrance, Minneapolis (laronidase)

      Completed
      • Cognitive Decline
      • +4 more
      • Oakland, California
      • +2 more
      Jan 22, 2016

      Mucopolysaccharidosis I, Hurler Syndrome, Hurler-Scheie Syndrome Trial in Worldwide (Aldurazyme (Recombinant Human

      Completed
      Has Results
      • Mucopolysaccharidosis I
      • +3 more
      • Aldurazyme (Recombinant Human Alpha-L-Iduronidase)
      • Lyon, France
      • +3 more
      Mar 17, 2015

      Mucopolysaccharidosis I, Hurler's Syndrome, Hurler-Scheie Syndrome Trial in Brazil, Canada (Aldurazyme (Recombinant Human

      Completed
      Has Results
      • Mucopolysaccharidosis I
      • +3 more
      • Aldurazyme (Recombinant Human Alpha-L-Iduronidase)
      • Florianopolis, Santa Catarina, Brazil
      • +4 more
      Mar 17, 2015

      Mucopolysaccharidosis I, Hurlers Syndrome, Hurler-Scheie Syndrome Trial in Canada, Germany, United States (rhIDU (recombinant

      Completed
      Has Results
      • Mucopolysaccharidosis I
      • +2 more
      • rhIDU (recombinant human-Alpha-L-Iduronidase)
      • Placebo
      • New York, New York
      • +3 more
      Mar 19, 2015