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MEK1

Showing 1 - 25 of 499
STUDY
CONDITIONS
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LAST UPDATED

Arteriovenous Malformations Trial (Trametinib tablet)

Not yet recruiting
  • Arteriovenous Malformations
  • Trametinib tablet
  • (no location specified)
Oct 17, 2023

Neurofibromatosis 1 (NF1), Plexiform Neurofibromas (PN) Trial run by the NCI (Selumetinib)

Active, not recruiting
  • Neurofibromatosis 1 (NF1)
  • Plexiform Neurofibromas (PN)
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
Jan 31, 2023

Cancer, Cancer Metastatic, BRAF V600E Trial in Indianapolis (Abemaciclib, LY3214996)

Recruiting
  • Cancer
  • +6 more
  • Indianapolis, Indiana
    Indiana University Hospital / IU Simon Cancer Center
Jan 12, 2023

Neurofibromatosis 1, Neurofibroma Plexiform Trial in Shanghai (Selumetinib)

Active, not recruiting
  • Neurofibromatosis 1
  • Neurofibroma Plexiform
  • Shanghai, China
  • +1 more
Jan 13, 2023

Neurofibromatosis 1, Neurofibromatosis Type 1, NF1 Trial run by the National Cancer Institute (NCI) (AZD6244)

Active, not recruiting
  • Neurofibromatosis 1
  • +3 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
Aug 24, 2022

Low-Grade Glioma, Recurrent Low-Grade Glioma, Progressive Low-Grade Glioma Trial in Memphis (Mirdametinib)

Recruiting
  • Low-Grade Glioma
  • +2 more
  • Memphis, Tennessee
    St. Jude Children's Research Hospital
Oct 24, 2022

Melanoma Stage III, In-Transit Metastasis of Cutaneous Melanoma Trial in Leiden (Encorafenib + Binimetinib)

Recruiting
  • Melanoma Stage III
  • In-Transit Metastasis of Cutaneous Melanoma
  • Encorafenib + Binimetinib
  • Leiden, Zuid-Holland, Netherlands
    Leiden University Medical Center
Mar 2, 2023

Advanced Solid Tumor (Phase 1), Pancreatic Adenocarcinoma, Malignant Melanoma (Cutaneous) Trial in United States (IMM-1-104)

Recruiting
  • Advanced Solid Tumor (Phase 1)
  • +4 more
  • Duarte, California
  • +4 more
Feb 2, 2023

Neurofibromatosis Type 1 Trial in Japan (Selumetinib)

Active, not recruiting
  • Neurofibromatosis Type 1
  • Minato-ku, Japan
  • +3 more
Jun 9, 2022

Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Malignant Tumor in the Brain, Metastatic Malignant Tumor in the CNS

Recruiting
  • Clinical Stage IV Cutaneous Melanoma AJCC v8
  • +3 more
  • Scottsdale, Arizona
  • +2 more
Jan 4, 2023

NSCLC Trial (Phase I - Mirdametinib - Level 1, Phase II - Mirdametinib, Phase I - Mirdametinib - Level 2)

Not yet recruiting
  • Non-Small Cell Lung Cancer
  • Phase I - Mirdametinib - Level 1
  • +4 more
  • (no location specified)
Jul 7, 2023

Gastrointestinal Cancer Trial in New York, Providence (Cobimetinib, Hydroxychloroquine, Atezolizumab)

Active, not recruiting
  • Gastrointestinal Cancer
  • New York, New York
  • +1 more
Nov 29, 2022

Pancreatic Ductal Adenocarcinoma Trial in Miami (Trametinib, Ruxolitinib, Retifanlimab)

Not yet recruiting
  • Pancreatic Ductal Adenocarcinoma
  • Miami, Florida
    University of Miami
Jun 27, 2022

Breast Cancer, Breast Cancer Stage IV, HER2-negative Breast Cancer Trial in United States (Mirdametinib, Fulvestrant)

Recruiting
  • Breast Cancer
  • +6 more
  • Middletown, New Jersey
  • +3 more
Dec 28, 2021

Sarcoma,Soft Tissue Trial in France (Cobimetinib, Atezolizumab)

Recruiting
  • Sarcoma,Soft Tissue
  • Angers, France
  • +4 more
Mar 28, 2022

Neurofibromatosis Type 1, Plexiform Neurofibroma, Optic Nerve Glioma Trial in London (Selumetinib)

Recruiting
  • Neurofibromatosis Type 1
  • +2 more
  • London, United Kingdom
  • +1 more
Nov 11, 2021

Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8 Trial in Houston

Recruiting
  • Recurrent Lung Non-Small Cell Carcinoma
  • +3 more
  • Durvalumab
  • +2 more
  • Houston, Texas
    M D Anderson Cancer Center
Oct 10, 2022

Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia Trial in Duarte (Cobimetinib, Enasidenib Mesylate)

Not yet recruiting
  • Recurrent Acute Myeloid Leukemia
  • Refractory Acute Myeloid Leukemia
  • Duarte, California
    City of Hope Medical Center
Jun 28, 2022

Solid Tumor, Colorectal Cancer Trial in Oxford (PF-02341066, PD-0325901, Binimetinib)

Completed
Has Results
  • Solid Tumor
  • Colorectal Cancer
  • Oxford, United Kingdom
    Oxford University Hospital NHS Trust
Jun 14, 2021

Tumor Skin, Metastatic Melanoma, Melanoma Trial in Orlando, Louisville (OBX-115)

Active, not recruiting
  • Tumor Skin
  • +2 more
  • OBX-115
  • Orlando, Florida
  • +1 more
Sep 28, 2023

Malignant Peripheral Nerve Sheath Tumors, Neurofibromatosis 1 Trial in United States (Selumetinib, Sirolimus)

Active, not recruiting
  • Malignant Peripheral Nerve Sheath Tumors
  • Neurofibromatosis 1
  • Washington, District of Columbia
  • +4 more
Apr 1, 2022

Grade 1 Glioma, Mixed Glio-neuronal Tumors, Pleomorphic Xanthoastrocytoma Trial in Strasbourg (Trametinib, Vinblastine)

Recruiting
  • Grade 1 Glioma
  • +2 more
  • Strasbourg, France
    CHU Strasbourg - France
Jul 7, 2022

Adamantinous Craniopharyngioma, Recurrent Adamantinomatous Craniopharyngioma Trial in Worldwide (Binimetinib Oral Tablet

Not yet recruiting
  • Adamantinous Craniopharyngioma
  • Recurrent Adamantinomatous Craniopharyngioma
  • Binimetinib Oral Tablet [Mektovi]
  • Aurora, Colorado
  • +17 more
Nov 28, 2022

Metastatic Malignant Tumor in the Brain Trial in Columbus (other, procedure, drug, radiation)

Active, not recruiting
  • Metastatic Malignant Neoplasm in the Brain
  • Laboratory Biomarker Analysis
  • +4 more
  • Columbus, Ohio
    Ohio State University Comprehensive Cancer Center
Oct 15, 2022

Metastatic Melanoma, BRAF Gene Mutation Trial in Lexington (Nilotinib 100mg, Nilotinib 200mg, Nilotinib 300mg)

Recruiting
  • Metastatic Melanoma
  • BRAF Gene Mutation
  • Nilotinib 100mg
  • +5 more
  • Lexington, Kentucky
    Markey Cancer Center
Jul 22, 2022