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R
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2 - 2018
Completed
Has Results
  • Dry Eye Syndrome
  • Andover, Massachusetts
    Andover, MA
2021-12-09
Dec 9, 2021
A
A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis - 2019
Completed
  • Allergic Conjunctivitis
  • Reproxalap Ophthalmic Solution (0.25%)
  • +2 more
  • Houston, Texas
    Slade & Baker Vision
2020-12-02
Dec 2, 2020
B
Microdosed Atropine 0.1% and 0.01% Ophthalmic Solutions for Reduction of Pediatric Myopia Progression
Recruiting
  • Myopia
  • Atropine 0.1% Ophthalmic Solution
  • +2 more
  • Birmingham, Alabama
  • +18 more
2021-12-14
Dec 14, 2021
R
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3
Active, not recruiting
  • Dry Eye Syndromes
  • Dry Eye
  • Phoenix, Arizona
  • +19 more
2021-11-01
Nov 1, 2021
E
Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults - 2021
Completed
  • Presbyopia
  • Pilocarpine Ophthalmic
  • Placebo
  • Azusa, California
  • +8 more
2021-08-05
Aug 5, 2021
A
A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber - 2019
Completed
  • Conjunctivitis, Allergic
  • Reproxalap Ophthalmic Solution (0.25%)
  • +2 more
  • Mississauga, Ontario, Canada
    Inflamax Research Limited
2020-05-11
May 11, 2020
M
Tavilermide Ophthalmic Solution for the Treatment of Dry Eye - 2020
Completed
  • Keratoconjunctivitis Sicca
  • Dry Eye
  • tavilermide ophthalmic solution
  • Placebo
  • Phoenix, Arizona
  • +21 more
2021-10-18
Oct 18, 2021
R
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1 - 2016
Completed
  • Dry Eye Syndrome
  • Andover, Massachusetts
    Andover, MA
2019-10-07
Oct 7, 2019
R
Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1 - 2020
Terminated
  • Neurotrophic Keratopathy
  • Lancaster, California
  • +10 more
2020-06-30
Jun 30, 2020
A
ALLEVIATE Trial - A Phase 3 Trial in Subjects With Allergic Conjunctivitis - 2018
Completed
  • Allergic Conjunctivitis
  • Reproxalap Ophthalmic Solution (0.25%)
  • +2 more
  • Phoenix, Arizona
  • +6 more
2019-10-30
Oct 30, 2019
M
Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye - 2011
Completed
  • Dry Eye
  • MIM-D3 Ophthalmic Solution
  • Placebo Ophthalmic Solution
  • Andover, Massachusetts
    Ora, Inc.
2019-08-15
Aug 15, 2019
A
Comparing Effects of Two Fixed Combinations Ophthalmic Solutions on Ocular Blood Flow - 2009
Completed
Has Results
  • Glaucoma
  • fixed combination of brimonidine tartrate 0.2% timolol maleate 0.5% ophthalmic solution
  • fixed combination of dorzolamide hydrochloride timolol maleate ophthalmic solution
  • Indianapolis, Indiana
    (unnamed)
2019-04-10
Apr 10, 2019
A
Bromfenac Versus Dexamethasone After Cataract Surgery - 2018
Completed
  • Inflammation Eye
  • Bromfenac 0.09 % Ophthalmic Solution
  • Dexamethasone 0.1% ophthalmic suspension
  • Reggio Emilia, RE, Italy
    Arcispedale Santa Maria Nuova IRCSS - Ophthalmology
2019-05-31
May 31, 2019
O
Study of Brimonidine Tartrate Nanoemulsion Eye Drops in Patients With Ocular Graft-vs-Host Disease - 2020
Completed
  • Graft Versus Host Disease
  • +7 more
  • Brimonidine Tartrate
  • Placebos
  • Phoenix, Arizona
  • +12 more
2020-06-30
Jun 30, 2020
J
A Study to Evaluate the Efficacy of Investigational OTC Eye Drops - 2017
Completed
Has Results
  • Ophthalmic Solutions
  • F# 13418-148 Eye Drops
  • +2 more
  • Andover, Massachusetts
    Andover Eye Associates
2018-08-24
Aug 24, 2018
O
A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients With Progressing Open Angle Glaucoma
Not yet recruiting
  • Open Angle Glaucoma
  • ONL1204 Ophthalmic solution (Dose A)
  • +2 more
  • Albury, New South Wales, Australia
  • +1 more
2021-12-06
Dec 6, 2021
A
An Exploratory Clinical Trial to Assess Safety and Tolerability in Subjects With Dry Eye Disease
Recruiting
  • Dry Eye
  • Reproxalap Ophthalmic Solution (0.25%)
  • Xiidra® (5% lifitegrast ophthalmic solution)
  • Mississauga, Ontario, Canada
    Cliantha Research
2022-01-12
Jan 12, 2022
A
Safety and Efficacy Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension - 2021
Completed
  • Primary Open Angle Glaucoma
  • Ocular Hypertension
  • Netarsudil ophthalmic solution 0.02%
  • Ripasudil hydrochloride hydrate ophthalmic solution 0.4%
  • Setagaya-Ku, Tokyo, Japan
    Seijo Clinic
2021-08-29
Aug 29, 2021
A
A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease
Recruiting
  • Dry Eye Disease
  • Reproxalap Ophthalmic Solution (0.25%)
  • Placebo Comparator
  • Andover, Massachusetts
    Andover Eye Associates
2022-02-08
Feb 8, 2022
A
The INVIGORATE 2 Trial: A Randomized, Double-masked, Crossover Design, Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis
Recruiting
  • Allergic Conjunctivitis
  • Reproxalap Ophthalmic Solution (0.25%)
  • Vehicle Ophthalmic Solution
  • Mississauga, Ontario, Canada
    Cliantha Research
2022-02-09
Feb 9, 2022
A
The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease - 2021
Completed
  • Dry Eye
  • Dry Eye Syndromes
  • Reproxalap Ophthalmic Solution (0.25%)
  • Vehicle Opthalmic Solution
  • Memphis, Tennessee
    University Clinical Health
2022-03-28
Mar 28, 2022
A
A Clinical Trial to Assess Subjects With Dry Eye Disease. - 2021
Completed
  • Dry Eye
  • Reproxalap Ophthalmic Solution (0.25%)
  • Vehicle Ophthalmic Solution
  • Andover, Massachusetts
    Andover Eye Associates
2021-12-08
Dec 8, 2021
F
A Study Evaluating Bilastine Ophthalmic Solution 0.6% in the Conjunctival Allergen Challenge (Ora-CAC®) Model. - 2018
Completed
Has Results
  • Allergic Conjunctivitis
  • Bilastine Ophthalmic Solution 0.6%
  • +2 more
  • Phoenix, Arizona
  • +5 more
2021-11-16
Nov 16, 2021
A
The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease
Recruiting
  • Dry Eye
  • Reproxalap Ophthalmic Solution (0.25%)
  • Vehicle Ophthalmic Solution
  • Raynham, Massachusetts
    Andover Eye Associates (Raynham)
2022-01-31
Jan 31, 2022
V
Study of VVN001 Ophthalmic Solution in Dry Eye Disease - 2021
Completed
  • Dry Eye
  • VVN001 Ophthalmic Solution 1%
  • +2 more
  • Durham, North Carolina
    Lexitas
2022-01-31
Jan 31, 2022