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Polymerase inhibitor

Showing 1 - 25 of 8,302
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Acute Myeloid Leukemia Trial in Baltimore (Decitabine, talazoparib)

Active, not recruiting
Has Results
  • Acute Myeloid Leukemia
  • Baltimore, Maryland
    University of Maryland Greenebaum Comprehensive Cancer Center
May 31, 2022

Ovarian Tumors, BRCA1 Protein, BRCA2 Protein Trial in Worldwide (KU-0059436 (AZD2281)(PARP inhibitor))

Active, not recruiting
  • Ovarian Neoplasms
  • +2 more
  • KU-0059436 (AZD2281)(PARP inhibitor)
  • Brussels, Belgium
  • +4 more
Dec 19, 2022

HRD and Resistance to PAPPi in EOC Patients

Recruiting
  • Epithelial Ovarian Cancer
  • +6 more
  • Testing of homologous recombination deficiency
  • Beijing, Beijing, China
    Lei Li
Mar 26, 2022

Ovarian Cancer, Ovarian Carcinoma, Platinum-resistant Ovarian Cancer Trial (Pamiparib, Surufatinib)

Not yet recruiting
  • Ovarian Cancer
  • +4 more
  • (no location specified)
Aug 8, 2022

Metastatic Malignant Solid Tumor, Unresectable Malignant Solid Tumor Trial (Biopsy, Diagnostic Imaging, Novobiocin Sodium)

Not yet recruiting
  • Metastatic Malignant Solid Neoplasm
  • Unresectable Malignant Solid Neoplasm
  • Biopsy
  • +2 more
  • (no location specified)
Jan 14, 2023

Advanced Solid Tumors Trial in United States (KSQ-4279, KSQ-4279 will be combined in separate cohorts, including combination

Recruiting
  • Advanced Solid Tumors
  • KSQ-4279
  • KSQ-4279 will be combined in separate cohorts, including combination with an oral PARPi (poly adenosine diphosphate-ribose polymerase inhibitor)
  • Boston, Massachusetts
  • +4 more
Apr 5, 2022

Advanced Solid Tumor, Metastatic Solid Tumor Trial (ART6043, Olaparib, Talazoparib)

Not yet recruiting
  • Advanced Solid Tumor
  • Metastatic Solid Tumor
  • (no location specified)
Jun 1, 2023

Tumors Trial in United States (GSK4524101, Niraparib)

Not yet recruiting
  • Neoplasms
  • San Francisco, California
  • +5 more
Oct 5, 2023

Ovarian Cancer, High Grade Serous Adenocarcinoma of Ovary, High Grade Endometrioid Ovarian Cancer Trial in Guangzhou (Fluzoparib

Not yet recruiting
  • Ovarian Cancer
  • +4 more
  • Guangzhou, Guangdong, China
    Sun Yat-sen University Cancer Cetntre
Sep 25, 2023

Endometrial Cancer Trial in Canada (Niraparib, TSR-042)

Active, not recruiting
  • Endometrial Cancer
  • Calgary, Alberta, Canada
  • +6 more
Nov 18, 2021

NSCLC, EGF-R Positive NSCLC Trial in Wuxi (Parimparib, Chemotherapy drug, Targeted Therapy Agent)

Recruiting
  • Carcinoma, Non-Small-Cell Lung
  • EGF-R Positive Non-Small Cell Lung Cancer
  • Wuxi, Jiangsu, China
    Affiliated Hospital of Jiangnan University
Jan 30, 2023

Homologous Recombination Deficiency in Chinese Ovarian Cancer

Not yet recruiting
  • Ovarian Cancer
  • +2 more
  • PARP inhibitor
  • Nanjing, Jiangsu, China
    Xiaoxiang Chen, MD,PhD
Sep 4, 2021

Covid19, SARS-CoV Infection Trial in Seattle (Zinc Picolinate, Resveratrol, Zinc Picolinate Placebo)

Terminated
  • Covid19
  • SARS-CoV Infection
  • Zinc Picolinate
  • +3 more
  • Seattle, Washington
    Swedish Medical Center
Jul 26, 2022

Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Kidney Cancer Trial in Baltimore (Olaparib)

Recruiting
  • Renal Cell Carcinoma
  • +4 more
  • Baltimore, Maryland
    Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Mar 14, 2022

Solid Tumor, Extensive-stage Small-cell Lung Cancer, Locally Advanced Breast Cancer Trial in Czechia, Poland (RP12146)

Recruiting
  • Solid Tumor
  • +6 more
  • HoĊ™ovice, Czechia
  • +5 more
Jun 8, 2022

Tumors, Breast Tumors Trial in Japan (talazoparib)

Active, not recruiting
Has Results
  • Neoplasms
  • Breast Neoplasms
  • Nagoya, Aichi, Japan
  • +7 more
Dec 20, 2021

Advanced Cancer, Metastatic Cancer, Breast Cancer Trial in United Kingdom, United States (ART4215, Talazoparib, Niraparib)

Recruiting
  • Advanced Cancer
  • +2 more
  • Orlando, Florida
  • +6 more
Aug 16, 2022

Recurrent Glioma, Recurrent Glioblastoma, Poly ADP Ribose Polymerase (PARP) Inhibitor Trial in Hong Kong (Talazoparib)

Recruiting
  • Recurrent Glioma
  • +4 more
  • Hong Kong, Hong Kong
    Department of Clinical Oncology
Aug 19, 2021

Advanced Malignant Solid Tumor, Clinical Stage III Gastroesophageal Junction Adenocarcinoma, Clinical Stage IV Gastroesophageal

Recruiting
  • Advanced Malignant Solid Neoplasm
  • +28 more
  • Trifluridine and Tipiracil Hydrochloride
  • Talazoparib Tosylate
  • Buffalo, New York
    Roswell Park Cancer Institute
Mar 2, 2022

Breast Tumors, Triple-Negative, Breast Tumor Malignant Female, Radiotherapy Side Effect Trial in Paris (Olaparib, Radiation

Active, not recruiting
  • Breast Neoplasms, Triple-Negative
  • +2 more
  • Paris, France
    Institut Curie
Oct 23, 2020

Metastatic Malignant Solid Tumor, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma Trial in United States

Active, not recruiting
  • Metastatic Malignant Solid Neoplasm
  • +4 more
  • Laboratory Biomarker Analysis
  • +4 more
  • Phoenix, Arizona
  • +14 more
Sep 1, 2022

Ovarian Cancer Trial in Worldwide (Olaparib, Ceralasertib, Placebo to match olaparib)

Withdrawn
  • Ovarian Cancer
  • Anchorage, Alaska
  • +25 more
Mar 9, 2021

Metastatic Breast Cancer Trial in Herlev, Vejle (PARP inhibitor 2X-121)

Active, not recruiting
  • Metastatic Breast Cancer
  • PARP inhibitor 2X-121
  • Herlev, Denmark
  • +1 more
Feb 1, 2023

Ovarian Cancer Recurrent Trial in Birmingham (M4344+Niraparib)

Not yet recruiting
  • Ovarian Cancer Recurrent
  • Birmingham, Alabama
    University of Alabama at Birmingham
Jan 5, 2023

Metastatic Solid Tumor, BRCA1 Mutation, BRCA2 Mutation Trial in San Francisco (Niraparib, Irinotecan)

Not yet recruiting
  • Metastatic Solid Tumor
  • +4 more
  • San Francisco, California
    University of California, San Francisco
Jan 12, 2023