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R04929097

Showing 1 - 25 of 25
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED

Recurrent Melanoma, Stage IV Skin Melanoma Trial in New York (Cisplatin, Gamma-Secretase Inhibitor RO4929097, Laboratory

Completed
Has Results
  • Recurrent Melanoma
  • Stage IV Skin Melanoma
  • New York, New York
    Memorial Sloan-Kettering Cancer Center
Oct 24, 2019

DS Stage I Plasma Cell Myeloma, DS Stage II Plasma Cell Myeloma, DS Stage III Plasma Cell Myeloma Trial in Tampa (procedure,

Withdrawn
  • DS Stage I Plasma Cell Myeloma
  • +3 more
  • Autologous Hematopoietic Stem Cell Transplantation
  • +5 more
  • Tampa, Florida
    Moffitt Cancer Center
Sep 27, 2017

Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage IV Prostate Cancer Trial in New Brunswick (,

Terminated
Has Results
  • Adenocarcinoma of the Prostate
  • +2 more
  • placebo
  • +2 more
  • New Brunswick, New Jersey
    Rutgers Cancer Institute of New Jersey
Oct 25, 2017

Lymphoma, Brain Tumors, Sarcoma Trial in Bethesda, Memphis (RO4929097, Dexamethasone)

Withdrawn
  • Lymphoma
  • +4 more
  • Bethesda, Maryland
  • +1 more
Jun 30, 2017

Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Recurrent Colon Cancer Trial in Rochester, New York, Columbus (FOLFOX

Withdrawn
  • Adenocarcinoma of the Colon
  • +7 more
  • FOLFOX regimen
  • +5 more
  • Rochester, Minnesota
  • +2 more
Apr 3, 2017

Tumors Trial in United States (RG4733)

Completed
  • Neoplasms
  • Aurora, Colorado
  • +6 more
Nov 1, 2016

Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma Trial in Canada, United

Completed
Has Results
  • Recurrent Fallopian Tube Carcinoma
  • +5 more
  • Gamma-Secretase Inhibitor RO4929097
  • Laboratory Biomarker Analysis
  • Beverly Hills, California
  • +11 more
Apr 17, 2017

Non-Squamous NSCLC Trial in Amsterdam (RO4929097)

Completed
  • Non-Squamous Non-Small Cell Lung Cancer
  • Amsterdam, Netherlands
    (unnamed)
Nov 1, 2016

Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma, Stage IV Renal Cell Cancer Trial in Canada (Gamma-Secretase

Completed
Has Results
  • Clear Cell Renal Cell Carcinoma
  • +2 more
  • Gamma-Secretase Inhibitor RO4929097
  • Laboratory Biomarker Analysis
  • Vancouver, British Columbia, Canada
  • +3 more
Jan 19, 2017

Acral Lentiginous Malignant Melanoma, Lentigo Maligna Malignant Melanoma, Nodular Malignant Melanoma Trial in United States

Terminated
Has Results
  • Acral Lentiginous Malignant Melanoma
  • +6 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • laboratory biomarker analysis
  • Mobile, Alabama
  • +177 more
May 6, 2016

Estrogen Receptor Negative, HER2/Neu Negative, Progesterone Receptor Negative Trial in Columbus (drug, other, procedure)

Terminated
  • Estrogen Receptor Negative
  • +8 more
  • Columbus, Ohio
    Ohio State University Comprehensive Cancer Center
Sep 3, 2015

Recurrent Non-Small Cell Lung Carcinoma, Stage IV NSCLC Trial in Houston (Erlotinib Hydrochloride, Gamma-Secretase Inhibitor

Terminated
  • Recurrent Non-Small Cell Lung Carcinoma
  • Stage IV Non-Small Cell Lung Cancer
  • Erlotinib Hydrochloride
  • +3 more
  • Houston, Texas
    M D Anderson Cancer Center
Sep 28, 2015

Acoustic Schwannoma, Adult Anaplastic (Malignant) Meningioma, Adult Anaplastic Astrocytoma Trial in New York, Charlottesville

Completed
  • Acoustic Schwannoma
  • +28 more
  • 3-Dimensional Conformal Radiation Therapy
  • +6 more
  • New York, New York
  • +1 more
Sep 28, 2015

Recurrent NSCLC, Stage IIIB NSCLC, Stage IV NSCLC Trial in Houston (gamma-secretase/Notch signalling pathway inhibitor

Terminated
Has Results
  • Recurrent Non-small Cell Lung Cancer
  • +2 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • +2 more
  • Houston, Texas
    M D Anderson Cancer Center
Oct 15, 2015

Estrogen Receptor Positive, HER2/Neu Negative, Male Breast Carcinoma Trial in United States (Exemestane, Gamma-Secretase

Terminated
  • Estrogen Receptor Positive
  • +6 more
  • Tampa, Florida
  • +3 more
May 22, 2015

Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage III Pancreatic Cancer Trial in Hamilton, Toronto

Completed
  • Adenocarcinoma of the Pancreas
  • +4 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • +3 more
  • Hamilton, Ontario, Canada
  • +1 more
Feb 21, 2014

Estrogen Receptor Negative, HER2/Neu Negative, Progesterone Receptor Negative Trial in Baltimore, Ann Arbor, Detroit

Terminated
  • Estrogen Receptor Negative
  • +7 more
  • Gamma-Secretase Inhibitor RO4929097
  • +4 more
  • Baltimore, Maryland
  • +2 more
Apr 14, 2015

Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer Trial in Aurora, Denver, Baltimore

Completed
Has Results
  • Adenocarcinoma of the Pancreas
  • +2 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • Aurora, Colorado
  • +2 more
Nov 19, 2014

Adult Solid Tumor Trial in Madison (Gamma-Secretase Inhibitor RO4929097, Ketoconazole, Rifampin)

Completed
  • Adult Solid Neoplasm
  • Gamma-Secretase Inhibitor RO4929097
  • +8 more
  • Madison, Wisconsin
    University of Wisconsin Hospital and Clinics
Dec 19, 2014

Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood CNS Choriocarcinoma, Childhood CNS Germinoma Trial in Canada, United

Terminated
  • Childhood Atypical Teratoid/Rhabdoid Tumor
  • +45 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • +3 more
  • Palo Alto, California
  • +11 more
Nov 4, 2014

Solid Tumor Trial in Vancouver, Hamilton, Toronto (gamma-secretase/Notch signalling pathway inhibitor RO4929097, diagnostic

Completed
  • Unspecified Adult Solid Tumor, Protocol Specific
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • +3 more
  • Vancouver, British Columbia, Canada
  • +2 more
Apr 1, 2014

Adenocarcinoma of the Pancreas, Stage IA Pancreatic Cancer, Stage IB Pancreatic Cancer Trial in United States (drug, other,

Terminated
  • Adenocarcinoma of the Pancreas
  • +4 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • +4 more
  • Beverly Hills, California
  • +5 more
Sep 27, 2013

Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer Trial in

Terminated
  • Estrogen Receptor-positive Breast Cancer
  • +4 more
  • Birmingham, Alabama
  • +2 more
Sep 27, 2013

Adult Anaplastic Oligodendroglioma, Adult Brain Stem Glioma, Adult Giant Cell Glioblastoma Trial in Toronto (drug, procedure,

Terminated
  • Adult Anaplastic Oligodendroglioma
  • +6 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • +3 more
  • Toronto, Ontario, Canada
    University Health Network-Princess Margaret Hospital
Feb 6, 2013

Stage IIIB Melanoma, Stage IIIC Melanoma, Stage IV Melanoma Trial in Bronx, New York (drug, other, procedure)

Withdrawn
  • Stage IIIB Melanoma
  • +2 more
  • gamma-secretase/Notch signalling pathway inhibitor RO4929097
  • +3 more
  • Bronx, New York
  • +1 more
Jan 30, 2013