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Synucleinopathies

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STUDY
CONDITIONS
INTERVENTIONS
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Multiple System Atrophy, Parkinson Disease Trial in New York (UB-312 Injection, Placebo Injection)

Not yet recruiting
  • Multiple System Atrophy
  • Parkinson Disease
  • UB-312 Injection
  • Placebo Injection
  • New York, New York
    NYU Langone Health
Nov 23, 2022

Parkinson's Disease and Other Synucleinopathies (EASE-PD)

Active, not recruiting
  • Parkinson's Disease
  • Multiple System Atrophy
    • Wuhan, Hubei, China
    • +3 more
    Nov 28, 2022

    Gut Microbiota in the Progression of Alpha-synucleinopathies

    Recruiting
    • REM Sleep Behavior Disorder
    • No intervention
    • Hong Kong, Hong Kong
      The Chinese University of Hong Kong
    May 18, 2022

    Rapid Eye Movement Sleep Behavior Disorder, Synucleinopathy Trial in Shanghai (Idebenone, Placebo)

    Recruiting
    • Rapid Eye Movement Sleep Behavior Disorder
    • Synucleinopathy
    • Shanghai, Shanghai, China
      Department of neurology, Ruijin Hospital, Shanghai Jiao Tong Uni
    Apr 26, 2022

    Alpha-synuclein Aggregates Across Biofluid Reservoirs in

    Active, not recruiting
    • Parkinson Disease
    • +3 more
    • Biomarker assay
    • Stony Brook, New York
      Stony Brook University Medical Center
    May 3, 2022

    Longitudinal Tracking of Patients Diagnosed With

    Not yet recruiting
    • Neurodegenerative Diseases
    • +4 more
    • (no location specified)
    Aug 16, 2022

    The Syn-Sleep Study

    Active, not recruiting
    • REM Sleep Behavior Disorder (iRBD)
    • Syn-One Test
    • Chandler, Arizona
      MD First Research
    Mar 3, 2023

    Natural History Study of Synucleinopathies

    Recruiting
    • Patients With Synucleinopathies
    • +7 more
      • Boston, Massachusetts
      • +7 more
      Dec 16, 2021

      18F-0502B PET Imaging Targeting a-synuclein in Diagnosis of

      Recruiting
      • Positron-Emission Tomography
      • Alpha Synuclein Pathology
        • Shanghai, China
          Huashan Hospital
        Mar 13, 2023

        REM Sleep Behavior Disorder, Parkinson Disease, Synucleinopathies Trial (Rasagiline)

        Not yet recruiting
        • REM Sleep Behavior Disorder
        • +2 more
        • (no location specified)
        Nov 6, 2022

        Parkinson Disease, Biomarkers, Rehabilitation Outcome Trial in Milan (Multidisciplinary Intensive Rehabilitation,

        Recruiting
        • Parkinson Disease
        • +14 more
        • Multidisciplinary Intensive Rehabilitation
        • Muscle-stretching and active mobilization exercises
        • Milan, Italy
          IRCCS S. Maria Nascente, Fondazione Don Carlo Gnocchi
        Jul 7, 2022

        Gut Microbiota Across Early Stages of Synucleinopathy: From

        Recruiting
        • REM Sleep Behavior Disorder
        • Colonoscopy
        • Hong Kong, Hong Kong
        • +1 more
        Oct 25, 2022

        North American Prodromal Synucleinopathy Consortium Stage 2

        Recruiting
        • REM Sleep Behavior Disorder
        • +5 more
          • Los Angeles, California
          • +8 more
          Apr 20, 2023

          Sleep Profiles in REM Sleep Behavior Disorder

          Recruiting
          • Rapid Eye Movement Sleep Behavior Disorder
            • Boston, Massachusetts
              Massachusetts General Hospital
            May 12, 2021

            a-synucleinopathy Neurodegeneration in the FDRs of RBD

            Completed
            • REM Sleep Behavior Disorder
            • Neurodegeneration
              • Hong Kong, Hong Kong
                Department of psychiatry, Faculty of Medicine, The Chinese Unive
              Aug 5, 2021

              Parkinsonian Disorders Trial in Bordeaux, Toulouse (V1: HGPO + meal and V2: + meal, V1: 75mg + meal and V2: HGPO 75mg + meal)

              Completed
              • Parkinsonian Disorders
              • V1: HGPO + meal and V2: placebo + meal
              • V1: placebo 75mg + meal and V2: HGPO 75mg + meal
              • Bordeaux, France
              • +1 more
              Aug 24, 2020

              First-degree Relatives of Psychiatric Disorders Comorbid With

              Completed
              • REM Sleep Behavior Disorder
                • Hong Kong, Hong Kong
                • +1 more
                May 25, 2021

                Biomarkers in Parkinsonian Syndromes

                Recruiting
                • Parkinsonian Syndromes
                • +3 more
                • CSF, blood and urine sampling
                • clinical measures of disease severity and progression
                • Limoges, France
                • +2 more
                Mar 30, 2022

                REM Sleep Behaviour Disorder Trial in Marseille (7T MRI)

                Not yet recruiting
                • REM Sleep Behaviour Disorder
                • 7T MRI
                • Marseille, France
                  Assistance - Publique Hôpitaux de Marseille
                Jul 27, 2023

                Optimization of Morphomer-based Alpha-synuclein PET Tracers

                Completed
                • Parkinson Disease
                • +4 more
                  • Lund, Skåne, Sweden
                    Skåne University Hospital, Dept of Neurology
                  Sep 23, 2021

                  Multiple System Atrophy Trial in Nashville (ATH434)

                  Recruiting
                  • Multiple System Atrophy
                  • Nashville, Tennessee
                    Vanderbilt University Medical Center
                  May 9, 2023

                  Conversion Into Idiopathic RBD. Italian Study

                  Recruiting
                  • REM Sleep Behavior Disorder
                    • Cagliari, Italy
                      Centro Interdipartimentale di Medicina del Sonno, Università deg
                    Feb 21, 2022

                    Multiple System Atrophy Trial in Nashville (ATH434)

                    Not yet recruiting
                    • Multiple System Atrophy
                    • Nashville, Tennessee
                      Vanderbilt University Medical Center
                    Feb 8, 2023

                    Alpha-synuclein RT-QuIC Assay asDiagnostic Technique in REM

                    Suspended
                    • Sleep Disorder Rem Sleep Behavior
                    • Parkinson's Disease, Lewy Body
                    • No Intervention
                    • Edinburgh, Lothian, United Kingdom
                      The University of Edinburgh
                    May 17, 2021

                    Multiple System Atrophy Trial in Christchurch, Grafton, Salford (ATH434 dose level 1, ATH434 dose level 2, Placebo)

                    Recruiting
                    • Multiple System Atrophy
                    • ATH434 dose level 1
                    • +2 more
                    • Nashville, Tennessee
                    • +8 more
                    Jan 23, 2023