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TLR8

Showing 1 - 25 of 670
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Head and Neck Tumors Trial (TransCon TLR7/8 Agonist, Pembrolizumab, TransCon IL-2 ß/?)

Not yet recruiting
  • Head and Neck Neoplasms
  • TransCon TLR7/8 Agonist
  • +2 more
  • (no location specified)
Aug 4, 2023

Hepatitis B, Chronic Trial in Worldwide (administration of SLGN in arm C, Discontinuation of NUC treatment in arms B and C)

Recruiting
  • Hepatitis B, Chronic
  • administration of SLGN in arm C
  • Discontinuation of NUC treatment in arms B and C
  • Lyon, France
  • +7 more
Mar 11, 2022

Hepatitis B, HIV Trial in Worldwide (Selgantolimod, Placebo)

Recruiting
  • Hepatitis B
  • HIV Infections
  • San Diego, California
  • +35 more
Jan 31, 2023

Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor Trial in Australia, United States (TransCon IL-2 ß/?,

Recruiting
  • Advanced Solid Tumor
  • +7 more
  • TransCon IL-2 β/γ
  • +4 more
  • Boston, Massachusetts
  • +7 more
Nov 16, 2022

HIV Trial in South Africa, United States (sD-NP-GT8 DNA, IL-12 DNA, Trimer 4571)

Not yet recruiting
  • HIV Infections
  • sD-NP-GT8 DNA
  • +4 more
  • Birmingham, Alabama
  • +5 more
Mar 10, 2023

Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor Trial in Australia, United States (TransCon TLR7/8

Recruiting
  • Advanced Solid Tumor
  • +6 more
  • Duarte, California
  • +12 more
Sep 21, 2022

Biomarkers of Trained Immunity Following MMR Vaccination

Completed
  • Covid19
  • Heterologous stimuli
  • Neutralization assay
  • Saint Louis, Missouri
    Washington University School of Medicine
Nov 24, 2021

Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8 Trial in Atlanta (VLP-encapsulated TLR9 Agonist CMP-001,,

Not yet recruiting
  • Metastatic Prostate Adenocarcinoma
  • Stage IV Prostate Cancer AJCC v8
  • VLP-encapsulated TLR9 Agonist CMP-001,
  • Nivolumab
  • Atlanta, Georgia
    Emory University Hospital/Winship Cancer Institute
Aug 26, 2022

Myeloid Malignancies, Lymphoid Malignancies Trial in Durham (NK Cell enriched-DLI only, NK-DLI + DUK-CPG-001)

Recruiting
  • Myeloid Malignancies
  • Lymphoid Malignancies
  • NK Cell enriched-DLI only
  • NK-DLI + DUK-CPG-001
  • Durham, North Carolina
    Duke University Health System
Mar 8, 2022

Locally Advanced Malignant Solid Tumor, Metastatic Pancreatic Adenocarcinoma, Stage IV Pancreatic Cancer AJCC v8 Trial in United

Recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • +3 more
  • Agonistic Anti-OX40 Monoclonal Antibody INCAGN01949
  • VLP-encapsulated TLR9 Agonist CMP-001
  • Scottsdale, Arizona
  • +3 more
Jun 1, 2022

Metastatic Pancreatic Adenocarcinoma, Refractory Pancreatic Adenocarcinoma, Stage IV Pancreatic Cancer AJCC v8 Trial in

Active, not recruiting
  • Metastatic Pancreatic Adenocarcinoma
  • +2 more
  • Nivolumab
  • +2 more
  • Sacramento, California
    University of California Davis Comprehensive Cancer Center
Dec 16, 2021

Asthma Trial in Germany, United Kingdom (GSK2245035 Nasal Spray Solution, Placebo Nasal Spray Solution)

Completed
Has Results
  • Asthma
  • GSK2245035 Nasal Spray Solution
  • Placebo Nasal Spray Solution
  • Frankfurt, Hessen, Germany
  • +5 more
Feb 26, 2021

Low Grade B Cell Lymphoma Trial in Stanford (VTX-2337 plus radiotherapy)

Terminated
Has Results
  • Low Grade B Cell Lymphoma
  • VTX-2337 plus radiotherapy
  • Stanford, California
    Stanford Cancer Center
Sep 23, 2019

SNPs in p53 and p53 Response Elements on Inflammatory Response

Completed
  • HIV-1 Seropositive
  • +3 more
    • Research Triangle Park, North Carolina
      NIEHS Clinical Research Unit (CRU)
    Jan 21, 2023

    Associated With Necrotizing Enterocolitis

    Unknown status
    • Neonatal Disease
    • Gene expression of inflammatory mediator (Interleukin 8) and recognition receptor of Toll like receptor (TLR4).
    • (no location specified)
    Sep 10, 2019

    Unfavorable Course of Sepsis in Children Based onComprehensive

    Recruiting
    • Sepsis
    • flow cytometry
    • +2 more
    • Minsk, Belarus
      Republican Research and Practical Centre for Epidemiology and Mi
    Nov 15, 2023

    Developmental Delay Trial in Aberdeen (Fine and gross motor treatment only, Reflex integration + fine and gross motor treatment)

    Active, not recruiting
    • Developmental Delay
    • Fine and gross motor treatment only
    • Reflex integration + fine and gross motor treatment
    • Aberdeen, Washington
      Aberdeen School District
    Apr 10, 2023

    HER2 Positive Solid Tumors Trial in Australia, Korea, Republic of, United States (SBT6050, pembrolizumab, Cemiplimab)

    Active, not recruiting
    • HER2 Positive Solid Tumors
    • Boston, Massachusetts
    • +11 more
    Jun 27, 2022

    Innate Inflammatory Response, Asthma, Nasal Allergy Trial in Cambridge (R848, Saline)

    Recruiting
    • Innate Inflammatory Response
    • +2 more
    • Cambridge, Cambridgeshire, United Kingdom
      Cambridge University Hospitals NHS Foundation Trust
    Aug 25, 2023

    Clinical Stage III Cutaneous Melanoma AJCC v8, Melanoma of Unknown Primary, Pathologic Stage IIIB Cutaneous Melanoma AJCC v8

    Recruiting
    • Clinical Stage III Cutaneous Melanoma AJCC v8
    • +5 more
    • Pembrolizumab
    • +2 more
    • Anchorage, Alaska
    • +162 more
    Aug 23, 2022

    Peripheral Artery Disease Trial in Shanghai (Drug eluting stent, drug coating balloon)

    Recruiting
    • Peripheral Artery Disease
    • Drug eluting stent
    • drug coating balloon
    • Shanghai, Shanghai, China
      Changhai Hospital of Shanghai
    Mar 20, 2023

    MicroRNAs and Cytokines in Peri-Implantitis Tissue

    Active, not recruiting
    • Peri-implantitis
      • Baghdad, Iraq
        Munir
      Mar 14, 2023

      Innate on the Inflammatory Response to Endotoxin

      Recruiting
      • Asthma
      • +4 more
        • Research Triangle Park, North Carolina
          NIEHS Clinical Research Unit (CRU)
        Dec 7, 2022

        Cervical Intraepithelial Neoplasia Grade 2/3, Cervical Squamous Cell Carcinoma In Situ, Cervical Squamous Intraepithelial

        Active, not recruiting
        Has Results
        • Cervical Intraepithelial Neoplasia Grade 2/3
        • +3 more
        • Chapel Hill, North Carolina
          UNC Lineberger Comprehensive Cancer Center
        Jan 28, 2022

        Mild Cognitive Impairment, Alzheimer Dementia Trial (CpG1018, Placebo)

        Not yet recruiting
        • Mild Cognitive Impairment
        • Alzheimer Dementia
        • (no location specified)
        Jan 3, 2023