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5,782 items
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I
Safety and Efficacy Evaluation of ET-01 Transplantation in Subjects With Transfusion Dependent β-Thalassaemia
Active, not recruiting
  • Transfusion Dependent Beta-Thalassaemia
  • ET-01
  • Tianjin, Tianjin, China
    Institute of Hematology & Blood Diseases Hospital
2021-12-09
Dec 9, 2021
C
Revlimid in Transfusion Dependent Patients
Active, not recruiting
Has Results
  • Myelodysplastic Syndrome
  • Revlimid (Lenalidomide)
  • New York, New York
    Columbia University Medical Center
2022-01-12
Jan 12, 2022
B
Efficacy and Safety of Low Dose Thalidomide in Transfusion Dependent Thalassemia - 2022
Completed
  • Thalassemia
  • Thalidomide and Hydroxyurea
  • Peshawar, Khyber Pakhtukhwa, Pakistan
    Blood Diseases Clinic
2022-03-10
Mar 10, 2022
E
A Safety and Efficacy Study Evaluating ET-01 in Subjects With Transfusion Dependent β-Thalassaemia
Recruiting
  • Transfusion Dependent Beta-Thalassaemia
  • ET-01
  • Guangzhou, Guangdong, China
  • +3 more
2021-08-26
Aug 26, 2021
T
Physical Activity in Transfusion Dependent Patients With Myelodysplastic Syndrome
Recruiting
  • Myelodysplastic Syndromes
  • Medical Device Usage and Evaluation
  • +3 more
  • Philadelphia, Pennsylvania
    Sidney Kimmel Cancer Center at Thomas Jefferson University
2021-07-19
Jul 19, 2021
E
Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload - 2012
Completed
Has Results
  • Thalassemia
  • Iron Overload
  • Combo Chelation with Deferasirox (Exjade) and Deferoxamine (DFO)
  • Oakland, California
    CHRCO
2021-07-20
Jul 20, 2021
E
A Study of Aezea® (Cenersen) in Transfusion Dependent Anemia Associated With Myelodysplastic Syndrome (MDS) - 2015
Terminated
  • Myelodysplastic Syndromes
  • Tampa, Florida
    H. Lee Moffitt Cancer Center & Research Institute
2021-02-18
Feb 18, 2021
R
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients
Active, not recruiting
  • Beta-Thalassemia
  • Sirolimus 0.5 mg
  • Ferrara, Italy
  • +1 more
2020-11-30
Nov 30, 2020
M
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies
Recruiting
  • Sickle Cell Disease
  • +7 more
  • Reduced Toxicity Ablative Regimen
  • +2 more
  • Minneapolis, Minnesota
    University of Minnesota Medical Center, Fairview
2021-09-10
Sep 10, 2021
O
Long-term Follow-up of Subjects Treated With OTL-300 for Transfusion Dependent Beta-thalassemia Study (TIGET-BTHAL)
Active, not recruiting
  • Beta Thalassaemia
  • Safety and Efficacy assessments
  • Milan, Italy
    Ospedale San Raffaele - Telethon Institute for Gene Therapy (OSR
2020-09-16
Sep 16, 2020
A
The Use of Trifluoperazine in Transfusion Dependent DBA - 2021
Terminated
  • Diamond Blackfan Anemia
  • Pure Red Cell Aplasia
  • Boston, Massachusetts
  • +1 more
2021-10-12
Oct 12, 2021
H
Long-term Clinical Study of CN128 in Thalassemia Patients
Active, not recruiting
  • Thalassemia
  • Iron Overload
  • CN128 Tablets
  • Nanning, Guangxi, China
    The First Affiliated Hospital Of Guangxi Medical University
2022-03-17
Mar 17, 2022
N
Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia - 2021
Terminated
Has Results
  • Diamond Blackfan Anemia
  • Manhasset, New York
    North Shore- LIJ campus of The Feinstein Institute for Medical R
2021-11-22
Nov 22, 2021
T
Efficacy and Safety of RBCs Derived From Mirasol-treated Whole Blood in Patients Requiring Chronic Transfusion (PRAISE) - 2018
Terminated
Has Results
  • Transfusion Dependent Thalassemia
  • Mirasol Red Blood Cells (MIR RBCs)
  • Reference Red Blood Cells (REF RBCs)
  • Oakland, California
  • +8 more
2021-03-31
Mar 31, 2021
U
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP)
Recruiting
  • Beta-Thalassemia
  • Sirolimus 0.5 mg
  • Ferrara, FE, Italy
  • +3 more
2021-11-11
Nov 11, 2021
S
A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)
Active, not recruiting
  • Transfusion Dependent Beta-thalassemia
  • ST-400 Investigational product
  • Los Angeles, California
  • +5 more
2022-03-23
Mar 23, 2022
C
A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia
Active, not recruiting
Has Results
  • Thalassemia
  • Los Angeles, California
  • +13 more
2021-10-18
Oct 18, 2021
F
Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome - 2018
Terminated
Has Results
  • Anemia
  • Myelodysplastic Syndrome
  • Seattle, Washington
    Fred Hutch/University of Washington Cancer Consortium
2020-06-12
Jun 12, 2020
I
Gene Therapy for Transfusion Dependent Beta-thalassemia
Unknown status
  • Beta-Thalassemia
  • Autologous hematopoietic stem cells genetically modified with GLOBE lentiviral vector encoding for the human beta-globin gene
  • Milano, Italy
    Ospedale San Raffaele
2019-06-26
Jun 26, 2019
K
The Efficacy and Safety of Lenalidomide Monotherapy in Red Blood Cell Transfusion Dependent Subjects With Myelodysplastic Syndrome (MDS) Associated With Del (5q) Abnormality - 2016
Completed
  • Myelodysplastic Syndromes
  • London, United Kingdom
    King's College Hospital NHS Foundation Trust
2019-02-26
Feb 26, 2019
C
Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients - 2017
Completed
Has Results
  • Chronic Iron Overload
  • Lushnjë, Albania
  • +21 more
2021-04-08
Apr 8, 2021
G
A Trial Testing Early vs Late Onset of EPO Alfa Treatment in Lower Risk MDS
Recruiting
  • Myelodysplastic Syndromes
  • Amiens, France
  • +38 more
2020-12-01
Dec 1, 2020
C
Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia - 2017
Completed
Has Results
  • Thalassemia Major With Severe Transfusional Iron Overload
  • Deferasirox and deferiprone
  • Chicago, Illinois
  • +1 more
2019-02-13
Feb 13, 2019
C
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia - 2021
Completed
Has Results
  • Erythrocyte Transfusion
  • Beta-Thalassemia
  • Los Angeles, California
  • +72 more
2022-01-21
Jan 21, 2022
C
Cerebrovascular Reserve and White Matter Disease in Patients With Chronic Anemia
Recruiting
  • Thalassemia
  • +2 more
  • Los Angeles, California
    CHLA
2021-05-07
May 7, 2021