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Tumor-targeted gene medicine

Showing 1 - 25 of >10,000
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Advanced Malignant Solid Tumor Trial in United States (Adavosertib, Carboplatin, Everolimus)

Completed
Has Results
  • Advanced Malignant Solid Neoplasm
  • Aurora, Colorado
  • +7 more
Apr 11, 2022

Precision Medicine for Every Child With Cancer

Recruiting
  • Childhood Cancer
  • +5 more
  • Whole Genome Sequencing
  • +6 more
  • Adelaide, Australia
  • +8 more
Jan 24, 2023

Cancer Trial in Lexington (Therapeutic Intervention)

Recruiting
  • Cancer
  • Therapeutic Intervention
  • Lexington, Kentucky
    Markey Cancer Center, University of Kentucky
Nov 18, 2022

Liver Cell Carcinoma Trial in Houston (CATCH T cells, Cytoxan, Fludara)

Recruiting
  • Liver Cell Carcinoma
  • +7 more
  • CATCH T cells
  • +2 more
  • Houston, Texas
    Houston Methodist Hospital
Dec 19, 2022

Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI

Recruiting
  • Non-Small Cell Carcinoma of Lung, TNM Stage 4
  • +5 more
    • Aurora, Colorado
      University of Colorado, Cancer Center
    Nov 3, 2021

    Non-small Cell Lung Carcinoma, Urothelial Carcinoma, Gastrointestinal Carcinoma, Non-colon Trial in United States (afatinib,

    Completed
    • Non-small Cell Lung Carcinoma
    • +3 more
    • Denver, Colorado
    • +7 more
    Aug 17, 2022

    Multiple Myeloma Trial in Houston (TAA-specific CTLs, TAA-specific CTLs- fixed dose)

    Recruiting
    • Multiple Myeloma
    • TAA-specific CTLs
    • TAA-specific CTLs- fixed dose
    • Houston, Texas
      Houston Methodist Hospital
    Nov 11, 2022

    Frequency, Clinical Phenotype and Genetic Analysis of Heritable

    Not yet recruiting
    • Renal Tumor Histology
    • +13 more
    • Gene test
    • Shanghai, Shanghai, China
      Ethics Committee of Shanghai Renji Hospital
    Sep 6, 2022

    Neuroblastoma Trial in Houston (SNJB-JF-IL2 and SJNB-JF-Lptn + Dose Level 1 SKNLP, SNJB-JF-IL2 and SJNB-JF-Lptn + Dose Level 2

    Active, not recruiting
    • Neuroblastoma
    • SNJB-JF-IL2 and SJNB-JF-Lptn + Dose Level 1 SKNLP
    • SNJB-JF-IL2 and SJNB-JF-Lptn + Dose Level 2 SKNLP
    • Houston, Texas
      Texas Children's Hospital
    Mar 3, 2022

    Colorectal Tumors, Tumor Metastasis, Liver Tumors Trial in Shanghai (chemo ± targeted therapy)

    Completed
    • Colorectal Neoplasms
    • +3 more
    • chemotherapy ± targeted therapy
    • Shanghai, Shanghai, China
      Zhongshan hospital, Fudan university
    Jun 12, 2022

    Thyroid Cancer, Medullary, Neuroendocrine Tumor of the Lung Grade 1 and 2, Neuroendocrine Tumor of the Thymus Grade 1 and 2

    Recruiting
    • Thyroid Cancer, Medullary
    • +3 more
    • Basel, Switzerland
      University Hospital Basel, Clinic for radiology and nuclear medi
    May 23, 2022

    Neuroblastoma Trial in Houston (Neuroblastoma Vaccine (unmodified SKNLP, with gene-modified SJNB-JF-IL2 and SJNB-JF-LTN

    Active, not recruiting
    • Neuroblastoma
    • Neuroblastoma Vaccine (unmodified SKNLP, with gene-modified SJNB-JF-IL2 and SJNB-JF-LTN neuroblastoma cells
    • Cytoxan
    • Houston, Texas
      Texas Children's Hospital
    Mar 25, 2022

    Solid Tumor Trial in United States (NeoTCR-P1 adoptive cell therapy, nivolumab, IL-2)

    Suspended
    • Solid Tumor
    • NeoTCR-P1 adoptive cell therapy
    • +2 more
    • Duarte, California
    • +8 more
    Aug 16, 2022

    Solid Tumors Trial in Worldwide (RO7300490, Atezolizumab)

    Recruiting
    • Solid Tumors
    • København Ø, Denmark
    • +10 more
    Jan 31, 2023

    Metastatic Renal Cell Carcinoma Trial in Shanghai (sunitinib or pazopanib, PD-1 inhibitor combined with axitinib)

    Recruiting
    • Metastatic Renal Cell Carcinoma
    • sunitinib or pazopanib
    • PD-1 inhibitor combined with axitinib
    • Shanghai, Shanghai, China
      Renji Hospital, School of Medicine, Shanghai Jiao Tong Universit
    Apr 16, 2023

    Hodgkins Lymphoma, Non Hodgkins Lymphoma Trial in Houston (TAA-specific CTLs)

    Recruiting
    • Hodgkins Lymphoma
    • Non Hodgkins Lymphoma
    • TAA-specific CTLs
    • Houston, Texas
      Texas Children's Hospital
    Jul 14, 2022

    Molecular Study and Precision Medicine for Colorectal Cancer

    Not yet recruiting
    • Advanced Colorectal Carcinoma
    • Recurrent Colorectal Carcinoma
    • Molecular Profiling & drug testing in tumor organoids and PDXs
    • Wuhan, Hubei, China
      Wuhan Union Hospital, China
    May 30, 2023

    Unifying Advanced Treatment With Advanced Imaging

    Completed
    • Gastrointestinal Stromal Tumor (GIST)
    • Dual Energy CT
    • Mannheim, Germany
      University Center Mannheim
    Apr 6, 2022

    HER-2 Gene Amplification, HER2-positive Gastric Cancer, HER2-positive Breast Cancer Trial in United States (chimeric antigen

    Recruiting
    • HER-2 Gene Amplification
    • +4 more
    • chimeric antigen receptor (CAR) T cell therapy
    • Duarte, California
    • +6 more
    Aug 10, 2022

    Acute Myeloid Leukemia, Myelodysplastic Syndrome Trial in Houston (MultiTAA-specific T cells)

    Recruiting
    • Acute Myeloid Leukemia
    • Myelodysplastic Syndrome
    • MultiTAA-specific T cells
    • Houston, Texas
    • +1 more
    May 31, 2022

    Rhabdomyosarcoma Trial in Houston (TAA-Specific CTLs)

    Completed
    • Rhabdomyosarcoma
    • TAA-Specific CTLs
    • Houston, Texas
    • +1 more
    Apr 8, 2022

    Solid Tumor, Unspecified, Adult, Haematological Malignancy Trial in Aalborg

    Recruiting
    • Solid Tumor, Unspecified, Adult
    • Haematological Malignancy
      • Aalborg, Denmark
        Department of Oncology, Aalborg University Hospital
      Jan 20, 2023

      Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Embryonal Tumor Trial in Houston ((C7R)-GD2.CART cells, Cyclophosphamide,

      Recruiting
      • Diffuse Intrinsic Pontine Glioma
      • +3 more
      • (C7R)-GD2.CART cells
      • +2 more
      • Houston, Texas
        Texas Children's Hospital
      Feb 7, 2022

      (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX

      Active, not recruiting
      • Hemophilia B
      • +2 more
      • SB-318
      • +2 more
      • Oakland, California
      • +4 more
      Jan 30, 2023

      Solid Tumor, Adult Trial in Seoul (TAS-117)

      Completed
      • Solid Tumor, Adult
      • Seoul, Korea, Republic of
        Severance Hospital, Yonsei University Health System
      Apr 21, 2021