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antisense

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STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Quantification of Antisense HIV RNA in Patients

Recruiting
  • HIV-1-infection
  • Blood sampling
  • Paris, France
    Jean-Paul VIARD
Dec 21, 2022

Covid19 Trial in Rio De Janeiro, São Paulo (ISIS 721744, Normal Saline)

Completed
  • Covid19
  • ISIS 721744
  • Normal Saline
  • Rio De Janeiro, Brazil
  • +2 more
Sep 21, 2022

Solid Tumor, Adult, Carcinoma, Ovarian Epithelial, Fallopian Tube Tumors Trial in Houston (BP1001-A (Liposomal Grb2 Antisense

Not yet recruiting
  • Solid Tumor, Adult
  • +5 more
  • BP1001-A (Liposomal Grb2 Antisense Oligonucleotide)
  • BP1001-A (Liposomal Grb2 Antisense Oligonucleotide) with paclitaxel
  • (no location specified)
Jun 7, 2022

Mantle Cell Lymphoma, Peripheral T-cell Lymphoma (PTCL), Cutaneous T-cell Lymphoma (CTCL) Trial in Augusta, Nashville, Houston

Recruiting
  • Mantle Cell Lymphoma
  • +9 more
  • L-Bcl-2 antisense oligonucleotide
  • Augusta, Georgia
  • +2 more
Nov 18, 2022

Primary IgA Nephropathy Trial (RO7434656, Placebo)

Not yet recruiting
  • Primary IgA Nephropathy
  • (no location specified)
Mar 22, 2023

Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory Trial (BP1002; Liposomal Bcl-2 Antisense

Not yet recruiting
  • Acute Myeloid Leukemia, in Relapse
  • Acute Myeloid Leukemia Refractory
  • BP1002; Liposomal Bcl-2 Antisense Oligodeoxynucleotide
  • Decitabine (in combination with BP1002)
  • (no location specified)
Mar 8, 2022

Pancreatic Ductal Adenocarcinoma Trial (OT-101, FOLFIRINOX)

Not yet recruiting
  • Pancreatic Ductal Adenocarcinoma
  • (no location specified)
Oct 5, 2023

HIV Trial in Montpellier (20 ml blood test)

Not yet recruiting
  • HIV Infections
  • 20 ml blood test
  • Montpellier, Herault, France
    La Colombiere Hospital
Feb 8, 2022

Antisense Oligonucleotide for Spinal Muscular Atrophy

Recruiting
  • Spinal Muscular Atrophy
  • Beijing, Beijing, China
  • +2 more
Jan 11, 2022

Ulcerative Colitis Trial in Sacramento (Alicaforsen)

Completed
  • Ulcerative Colitis
  • Sacramento, California
    (unnamed)
Dec 1, 2022

Ulcerative Colitis Trial in Chicago (Alicaforsen)

Completed
  • Ulcerative Colitis
  • Chicago, Illinois
    (unnamed)
Dec 1, 2022

Crohn's Disease Trial in Worldwide (Alicaforsen)

Completed
  • Crohn's Disease
  • Kortrijk, Belgium
  • +15 more
Aug 11, 2022

Advanced Solid Tumors Trial (WGI-0301)

Not yet recruiting
  • Advanced Solid Tumors
  • (no location specified)
Jul 11, 2022

Lung Cancer Trial in Carlsbad, Cleveland (ISIS 3521, carboplatin, paclitaxel)

Completed
  • Lung Cancer
  • ISIS 3521
  • +2 more
  • Carlsbad, California
  • +1 more
Dec 1, 2022

End-stage Renal Disease (ESRD) Trial in Santiago De Compostela, Alcalá De Henares (ISIS 416858, Placebo)

Completed
  • End-stage Renal Disease (ESRD)
  • ISIS 416858
  • Placebo
  • Santiago De Compostela, A Coruna, Spain
  • +1 more
Dec 22, 2022

Healthy Participants Trial in Toronto (IONIS FXI-LRx, Placebo)

Completed
  • Healthy Participants
  • IONIS FXI-LRx
  • Placebo
  • Toronto, Ontario, Canada
    BioPharma Services Inc.
Jan 13, 2022

Rheumatoid Arthritis Trial in Canada, United States (ISIS 104838)

Completed
  • Rheumatoid Arthritis
  • ISIS 104838
  • Birmingham, Alabama
  • +30 more
Dec 1, 2022

Crohn's Disease Trial in Canada, United States (Alicaforsen)

Completed
  • Crohn's Disease
  • Little Rock, Arkansas
  • +29 more
Dec 1, 2022

Hypertension Trial in United States (IONIS-AGT-LRx, Placebo)

Completed
  • Hypertension
  • Placebo
  • ISIS 757456
  • Birmingham, Alabama
  • +8 more
Dec 21, 2022

Prostate Cancer Trial in Ann Arbor, Detroit (ARRx, Enzalutamide)

Suspended
  • Prostate Cancer
  • Ann Arbor, Michigan
  • +1 more
Dec 17, 2021

Hereditary Angioedema Trial in Netherlands, United States (IONIS-PKK-LRx, Placebo)

Completed
  • Hereditary Angioedema
  • Scottsdale, Arizona
  • +7 more
Sep 15, 2022

Amyloidosis Trial in Boston (Inotersen)

Active, not recruiting
  • Amyloidosis
  • Boston, Massachusetts
    Brigham and Women's Hospital
Dec 3, 2020

Retinitis Pigmentosa, Usher Syndrome Type 2 Trial in Canada, France, United States (RNA antisense oligonucleotide for

Terminated
  • Retinitis Pigmentosa
  • Usher Syndrome Type 2
  • RNA antisense oligonucleotide for intravitreal injection
  • Boston, Massachusetts
  • +6 more
Dec 12, 2022

Malignant Glioma, Tumors Trial in Philadelphia (IGF-1R/AS ODN; Surgery with tissue harvest and implantation 20 diffusion

Completed
  • Malignant Glioma
  • Neoplasms
  • IGF-1R/AS ODN; Surgery with tissue harvest and implantation 20 diffusion chambers in the rectus sheath with IGF-1R/AS ODN within 24 hours of craniotomy, implanted for 48 hours.
  • Philadelphia, Pennsylvania
    Thomas Jefferson University Hospital
Oct 5, 2020

Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind Trial in Dallas, Madison, London (QR-421a, Sham-procedure)

Active, not recruiting
  • Retinitis Pigmentosa
  • +7 more
  • Dallas, Texas
  • +2 more
Apr 21, 2022