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positive allosteric modulator

Showing 1 - 25 of >10,000
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Cognitive Impairment Trial in Nashville (Single Dose of VU319, Single Dose Placebo, Fed State)

Completed
  • Cognitive Impairment
  • Single Dose of VU319
  • +5 more
  • Nashville, Tennessee
    Vanderbilt Medical Center
Feb 5, 2020

Alcohol Use Disorder Trial in Charleston (Placebo, GET73)

Recruiting
  • Alcohol Use Disorder
  • Charleston, South Carolina
    Charleston Alcohol Research Center, Institute of Psychiatry, Med
Jan 5, 2022

Generalized Anxiety Disorder Trial (ENX-102, Placebo)

Not yet recruiting
  • Generalized Anxiety Disorder
  • (no location specified)
Feb 28, 2023

Essential Tremor Trial in United States (CAD-1883)

Completed
Has Results
  • Essential Tremor
  • Anniston, Alabama
  • +6 more
Jul 12, 2021

Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia Trial in Houston (Asciminib)

Recruiting
  • Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia
  • Houston, Texas
    M D Anderson Cancer Center
Feb 1, 2022

Androgen Receptor Positive, Estrogen Receptor Negative, HER2/Neu Negative Trial in United States (drug, other, biological)

Active, not recruiting
Has Results
  • Androgen Receptor Positive
  • +5 more
  • Corona, California
  • +6 more
Jun 8, 2022

Alcohol Use Disorder, Alcohol Drinking, Alcohol Use Disorder (AUD) Trial in Los Angeles, Aurora, Providence (ASP8062, Placebo)

Recruiting
  • Alcohol Use Disorder
  • +2 more
  • Los Angeles, California
  • +2 more
Jan 26, 2022

Partial Epilepsy Trial (YKP3089)

Approved for marketing
  • Partial Epilepsy
  • (no location specified)
Jan 25, 2022

Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer Trial in Miami (AI+CDK4/6i, SERD+CDK4/6i, mTOR inhibitor +

Not yet recruiting
  • Breast Cancer
  • +3 more
  • Miami, Florida
    University of Miami
Apr 12, 2023

Schizophrenia, Schizoaffective Disorder Trial in New York (AVL-3288, Placebo)

Completed
  • Schizophrenia
  • Schizoaffective Disorder
  • New York, New York
    New York State Psychiatric Institute
Jan 17, 2019

CENOBAMATE as Adjunctive Treatment in Patients Suffering From

Recruiting
  • Focal Onset Seizure
  • Epilepsy
    • Bron, France
    • +22 more
    Mar 6, 2023

    Panic Disorder Trial in Leiden (CVL-865 High dose, Alprazolam 1mg XR, Placebo)

    Completed
    • Panic Disorder
    • CVL-865 High dose
    • +3 more
    • Leiden, Zernikedreef 8, Netherlands
      Centre for Human Drug Research
    Jan 10, 2022

    MDD Trial (GATE-251, Placebo)

    Completed
    • Major Depressive Disorder
    • (no location specified)
    Jul 28, 2021

    Focal Onset Seizures Trial in Worldwide (JNJ-40411813, Placebo)

    Recruiting
    • Focal Onset Seizures
    • Tucson, Arizona
    • +62 more
    May 25, 2022

    Breast Cancer, Early-stage Breast Cancer, High Risk Breast Carcinoma Trial in United States (Abemaciclib, Tamoxifen,

    Not yet recruiting
    • Breast Cancer
    • +2 more
    • Boston, Massachusetts
    • +7 more
    Aug 14, 2023

    Solid Tumor Trial in Worldwide (BDTX-189)

    Terminated
    • Solid Tumor
    • Scottsdale, Arizona
    • +37 more
    Oct 13, 2022

    CML, Chronic Phase, CML, Accelerated Phase Trial in Wuhan (HS-10382(Part 1: Dose escalation), HS-10382(Part 2: Dose expansion))

    Recruiting
    • CML, Chronic Phase
    • CML, Accelerated Phase
    • HS-10382(Part 1: Dose escalation)
    • HS-10382(Part 2: Dose expansion)
    • Wuhan, Hubei, China
      Union Hospital affiliated to Tongji Medical College of Huazhong
    Jan 12, 2023

    Cystic Fibrosis, Mucociliary Clearance Defect Trial in Iowa City, Columbia (Symptom driven performance of airway clearance,

    Not yet recruiting
    • Cystic Fibrosis
    • Mucociliary Clearance Defect
    • Symptom driven performance of airway clearance
    • Continuous daily performance of airway clearance
    • Columbia, Missouri
      University of Missouri Hospital and Clinics
    Dec 12, 2022

    Breast Cancer Recurrent Trial in Worldwide (Palbociclib 125mg, Standard endocrine therapy)

    Recruiting
    • Breast Cancer Recurrent
    • Palbociclib 125mg
    • Standard endocrine therapy
    • Graz, Austria
    • +52 more
    Nov 15, 2022

    Breast Cancer. Real Clinical Practice in Russia

    Recruiting
    • Breast Cancer
    • Neoadjuvant Endocrine Therapy
    • Tamoxifen 20mg
    • +4 more
    • Moscow, Russian Federation
      Blokhin's Russian Cancer Research Center
    Apr 5, 2023

    Effectiveness of CFTR Modulators According to Co-therapy

    Not yet recruiting
    • Cystic Fibrosis
    • Discontinuation of respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)
    • (no location specified)
    Dec 15, 2022

    Healthy Trial in Merksem (Adalimumab, Lipopolysaccharide (LPS))

    Recruiting
    • Healthy
    • Merksem, Belgium
      Clinical Pharmacology Unit
    May 22, 2023

    Depression Trial in Moldova, Republic of, Romania (JNJ-39393406, Placebo)

    Completed
    • Depression
    • Codru, Moldova, Republic of
    • +3 more
    May 20, 2020

    Glioblastoma Multiforme of Brain Trial in Tübingen (Multipeptide plus XS15)

    Recruiting
    • Glioblastoma Multiforme of Brain
    • Multipeptide plus XS15
    • Tübingen, BW, Germany
      University Hospital Tübingen
    May 9, 2022

    Bipolar Depression, MDD Trial in Chi?inau (Palmitoylethanolamide)

    Recruiting
    • Bipolar Depression
    • Major Depressive Disorder
    • Chișinău, Moldova, Republic of
      State University of Medicine and Pharmacy " Nicolae Testemitsanu
    Sep 26, 2023