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siRNA

Showing 1 - 25 of 131
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FXI Trial in Creve Coeur (FXI-GalNAc-siRNA, Placebo)

Recruiting
  • FXI
  • Creve Coeur, Missouri
    Biopharma
May 3, 2023

Nonalcoholic Steatohepatitis, Genetic Risk Factor Trial (ALN-PNP Dose Level 1, ALN-PNP Dose Level 2, ALN-PNP Dose Level 3)

Not yet recruiting
  • Nonalcoholic Steatohepatitis
  • Genetic Risk Factor
  • ALN-PNP Dose Level 1
  • +3 more
  • (no location specified)
Sep 5, 2023

German Inclisiran Network: Retrospective Registry of Patients

Recruiting
  • Hypercholesterolemia
    • Jena, Germany
      Jena University Hospital
    Jul 4, 2022

    Healthy Trial in Glendale (ALN-PNP, Placebo (PB))

    Recruiting
    • Healthy
    • Glendale, California
      California Clinical Trials Medical Group
    Jan 31, 2023

    Paroxysmal Nocturnal Hemoglobinuria (PNH) Trial in Brisbane (ADX-038, Placebo)

    Not yet recruiting
    • Paroxysmal Nocturnal Hemoglobinuria (PNH)
    • Brisbane, Queensland, Australia
      Nucleus Network Brisbane
    May 17, 2023

    Metastatic Malignant Tumor in the Brain, Metastatic Solid Tumor, Recurrent Colorectal Carcinoma Trial in Winston-Salem

    Completed
    • Metastatic Malignant Neoplasm in the Brain
    • +11 more
    • Laboratory Biomarker Analysis
    • siRNA-transfected Peripheral Blood Mononuclear Cells APN401
    • Winston-Salem, North Carolina
      Comprehensive Cancer Center of Wake Forest University
    Aug 5, 2022

    Hereditary Angioedema Trial in Adelaide (ADX-324, Placebo)

    Recruiting
    • Hereditary Angioedema
    • Adelaide, South Australia, Australia
      CMAX Clinical Research
    Jan 10, 2023

    HNSCC, Melanoma, Gynecologic Cancer Trial in Portland (DP CD8 TIL, DP CD8 TIL KD, Low dose IL-2)

    Recruiting
    • HNSCC
    • +5 more
    • DP CD8 TIL
    • +2 more
    • Portland, Oregon
      Providence Portland Medical Center
    Jun 5, 2023

    PH1, Primary Hyperoxaluria, RNAi Therapeutic Trial in Worldwide (Lumasiran)

    Active, not recruiting
    • PH1
    • +4 more
    • Bordeaux, France
    • +8 more
    Jan 13, 2023

    Healthy Trial in Antwerp (Pozelimab, Cemdisiran)

    Completed
    • Healthy
    • Antwerp, Belgium
      Regeneron Research Site
    Nov 11, 2021

    Idiopathic Pulmonary Fibrosis Trial in Adelaide (SRN-001, Placebo)

    Not yet recruiting
    • Idiopathic Pulmonary Fibrosis
    • Adelaide, South Australia, Australia
      CMAX Clinical Research
    Aug 2, 2023

    Non-transfusion-dependent Thalassemia, Low Risk Myelodysplastic Syndrome Trial in Bulgaria, United Kingdom (SLN124 is a GalNAc

    Withdrawn
    • Non-transfusion-dependent Thalassemia
    • Low Risk Myelodysplastic Syndrome
    • SLN124 is a GalNAc conjugated double stranded fully modified siRNA. Sodium chloride 0.9% w/v is used as Placebo
    • Kyustendil, Bulgaria
    • +4 more
    Apr 23, 2020

    Hypertrophic Scar Trial (STP705)

    Not yet recruiting
    • Hypertrophic Scar
    • (no location specified)
    Jun 8, 2022

    Thrombosis Trial in Perth (SRSD107, Placebo)

    Not yet recruiting
    • Thrombosis
    • Perth, Other (Non U.s.), Australia
      Linear Clinical Research
    Nov 2, 2023

    COVID-19 Trial in Moscow (MIR 19 ®, Standard therapy)

    Completed
    • COVID-19
    • MIR 19 ®
    • Standard therapy
    • Moscow, Russian Federation
      NRC Institute of Immunology FMBA
    Mar 24, 2023

    Gliosarcoma, Recurrent Glioblastoma Trial in Chicago (Laboratory Biomarker Analysis, Pharmacological Study, Targeted Molecular

    Completed
    Has Results
    • Gliosarcoma
    • Recurrent Glioblastoma
    • Laboratory Biomarker Analysis
    • +2 more
    • Chicago, Illinois
      Northwestern University
    Aug 5, 2022

    Healthy Volunteer Study Trial in San Antonio (CBP-4888, Placebo)

    Recruiting
    • Healthy Volunteer Study
    • San Antonio, Texas
      Comanche Biopharma Clinical Research Site #1
    Jun 1, 2023

    Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (Disorder) Trial in Los Angeles (MBS-COV, Placebo)

    Recruiting
    • Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (Disorder)
    • Los Angeles, California
      Phase I Unit
    Jan 10, 2023

    Transthyretin-Mediated Amyloidosis Trial in London (ALN-TTRSC04, Placebo)

    Not yet recruiting
    • Transthyretin-Mediated Amyloidosis
    • London, United Kingdom
      Clinical Trial Site
    Dec 15, 2022

    Healthy Trial in Toronto (ABX1100 injection for IV infusion, Placebo injection for IV infusion)

    Recruiting
    • Healthy
    • ABX1100 injection for IV infusion
    • Placebo injection for IV infusion
    • Toronto, Canada
      Study Site
    Oct 25, 2023

    Chronic Hepatitis B Trial (Imdusiran (AB-729))

    Not yet recruiting
    • Chronic Hepatitis B
    • Imdusiran (AB-729)
    • (no location specified)
    Nov 30, 2023

    Familial Chylomicronemia Syndrome Trial (VSA001 injection, Placebo)

    Not yet recruiting
    • Familial Chylomicronemia Syndrome
    • VSA001 injection
    • Placebo
    • (no location specified)
    Jun 9, 2023

    Cardiovascular Diseases, Atherosclerosis, Lipoprotein(a) Trial (SLN360, Placebo)

    Not yet recruiting
    • Cardiovascular Diseases
    • +2 more
    • (no location specified)
    Sep 12, 2022

    Polycythemia Vera Trial (SLN124, Placebo)

    Not yet recruiting
    • Polycythemia Vera
    • (no location specified)
    Aug 10, 2022

    Inclisiran on Major Adverse Cardiovascular Events in French

    Not yet recruiting
    • Atherosclerotic Cardiovascular Disease
    • Inclisiran sodium
    • +3 more
    • (no location specified)
    Jul 26, 2023