Clincosm LogoSign in Get a demo

24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease

Sponsor
Chinese PLA General Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT05550467
Collaborator
(none)
10,000
Enrollment
102.9
Actual Duration (Months)

Study Details

Study Description

Brief Summary

Association between excretion pattern and development trajectory of urinary electrolytes (urine sodium, urine potassium, urine chlorine, urine magnesium, urine calcium, urine phosphorus, urine creatinine, urea, uric acid, urine glucose, urine protein, urine retinol) and adverse prognosis in patients with chronic kidney disease

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    10000 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    24-hour Urinary Electrolyte Excretion and Renal Prognosis in Chronic Kidney Disease：a Retrospective Cohort Study
    Actual Study Start Date :
    Jan 1, 2014
    Actual Primary Completion Date :
    Jul 30, 2022
    Actual Study Completion Date :
    Jul 31, 2022

    Outcome Measures

    Primary Outcome Measures

    1. Kidney disease progression [2014.1.1-2022.7.31]

      eGFR decline > 50%; dialysis; kidney transplant

    2. Death [2014.1.1-2022.7.31]

      All cause death

    Secondary Outcome Measures

    1. Cardiovascular disease [2014.1.1-2022.7.31]

      myocardial infarction, angina pectoris, stable heart failure, peripheral artery disease , revascularization, cerebrovascular events

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 100 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • Our study is a retrospective cohort study. The study included patients with adult（Age≥18years）CKD who were hospitalized in the Department of Nephrology, First Medical Center of Chinese PLA General Hospital from January 2014 to July 2022. Patients with CKD who had one or more 24-hour urinary electrolyte excretion tests at intervals of more than three months were included in the subgroup analysis.
    Exclusion Criteria:
    • Patients with hemodialysis therapy and urine volume less than 500ml were excluded.

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Chinese PLA General Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    LIANG Shuang, Dr., Chinese PLA General Hospital
    ClinicalTrials.gov Identifier:
    NCT05550467
    Other Study ID Numbers:
    • 2015BAI12B06-03
    First Posted:
    Sep 22, 2022
    Last Update Posted:
    Sep 22, 2022
    Last Verified:
    Sep 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Kidney Diseases
    Renal Insufficiency, Chronic

    Study Results

    No Results Posted as of Sep 22, 2022