5 Year Follow-up of Adolescents With Knee Pain

Sponsor
Aalborg University (Other)
Overall Status
Completed
CT.gov ID
NCT02873143
Collaborator
Research Unit of General Practice, Aalborg (Other), University of Southern Denmark (Other), Copenhagen University Hospital, Denmark (Other)
540
4

Study Details

Study Description

Brief Summary

The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown.

In 2011, a cohort of 2200 adolescents aged 15 to 19 years answered an online questionnaire on musculoskeletal pain. Of these, 504 reported knee pain, and 153 of these were clinically diagnosed with PFP. Now, after 5 years, the 504 adolescents, as well as 252 randomly selected adolescents who did not report knee pain in 2011, will be contacted again to gain insights into their prognosis.

Condition or Disease Intervention/Treatment Phase
  • Other: No intervention

Study Design

Study Type:
Observational
Actual Enrollment :
540 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
5 Year Follow-up of Adolescents With Knee Pain - a Prospective Cohort Study of 504 Adolescents
Study Start Date :
Sep 1, 2016
Actual Primary Completion Date :
Dec 1, 2016
Actual Study Completion Date :
Jan 1, 2017

Arms and Interventions

Arm Intervention/Treatment
The APA2011 cohort

In September 2011, students at 4 upper secondary schools in Aalborg were invited to answer an online questionnaire and to be part of the APA2011 cohort. From 2846 potential responders, 2200 adolescents responded to the questionnaire, corresponding to a response rate of 77%. A total of 504 adolescents indicating knee pain at least monthly were successfully contacted (a response rate of 83% of those who reported their telephone numbers) and were asked standardized questions on the telephone. This forms the cohort of 504 adolescents with knee pain. In addition a random selected group of adolescents without knee pain in 2011 will be contacted and asked the same questions as those with knee pain.

Other: No intervention
No intervention

Outcome Measures

Primary Outcome Measures

  1. Knee pain during the last week [5 years]

    All subjects are asked if they experienced knee pain during the last week

Secondary Outcome Measures

  1. Knee pain during the last 30 days [5 years]

    Did you experience knee pain during the last 30 days?

  2. Frequency of knee pain [5 years]

    Frequency of knee pain divided into (almost daily, several times per week, weekly, monthly, rarely, never

  3. When did your knee pain resolve [5 years]

  4. Pain in other regions of the body [5 years]

  5. Seeking medical attention for your knee pain [5 years]

  6. Previous treatments for your knee pain [5 year]

  7. Use of pain medication [5 years]

  8. Worst pain last week [5 years]

    Measured on a numeric rating scale

  9. Knee Injury and Osteoarthritis Outcome score [5 years]

  10. Health-related quality of life [5 years]

    Measure with the EQ-5D-3L

  11. The influence of knee pain on choice of activity level, mood, choice of education and professional career [5 years]

  12. Physical activity level [5 years]

    Measured with the IPAQ

  13. Number of sports participation per week [5 years]

  14. The effect of knee pain on sports participation [5 years]

  15. Self-reported sleep problems [5 years]

    Assessed by asking three questions related to: trouble falling asleep, wake several times per night and trouble staying asleep.

Eligibility Criteria

Criteria

Ages Eligible for Study:
15 Years to 19 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
From the 504, 153 were diagnosed with PFP, the criteria for which included:
  • insidious onset of anterior knee or retropatellar pain for longer than 6 weeks that was provoked by at least 2 of the following: prolonged sitting or kneeling, squatting, running, hopping, or stair climbing; tenderness on palpation of the patella; pain when stepping down; or double-leg squatting.
Exclusion criteria were:
  • concomitant injury or pain from the hip, lumbar spine, or other knee structures

  • self-reported patellofemoral instability

  • knee joint effusion.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Aalborg University
  • Research Unit of General Practice, Aalborg
  • University of Southern Denmark
  • Copenhagen University Hospital, Denmark

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Michael Skovdal Rathleff, Senior researcher, Aalborg University
ClinicalTrials.gov Identifier:
NCT02873143
Other Study ID Numbers:
  • 2011-0020
First Posted:
Aug 19, 2016
Last Update Posted:
Jan 27, 2017
Last Verified:
Jan 1, 2017
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jan 27, 2017