The Accuracy of Detection of Artificial Intelligence Second Mesio-buccal Canal of Maxillary First Molars on CBCT Images

Sponsor
Cairo University (Other)
Overall Status
Recruiting
CT.gov ID
NCT05340140
Collaborator
(none)
50
1
17
2.9

Study Details

Study Description

Brief Summary

CAD systems are computer applications that assist in the detection and/or diagnosis of diseases by providing an unbiased "second opinion" to the image interpreter, aiming at improving accuracy and reducing time for analysis. With the rapid growth of Deep Learning (DL) algorithms in image-based applications, CAD systems can now be trained by DL to provide more advanced capability (ie, the capability of artificial intelligence [AI]) to best assist clinicians.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: deep learning model

Detailed Description

Countless studies and discussions have been based on the existence of a second canal in the mesiobuccal (MB) root of the maxillary molars , since it is strongly believed that one of the foremost reasons for endodontic failure in maxillary first molars is the difficulty of detecting and treating those second mesiobuccal (MB2) canals .The literature reveals that although MB2 canals of maxillary first molars have been found in more than 70% of in vitro studies , they were detected clinically in less than 40% of cases . Cone beam computed tomography (CBCT) is an imaging modality in the field of endodontics that has several advantages, including the ability to perform three-dimensional (3D) imaging of root canal systems with lower radiation doses, higher resolution, and no superimposition . Researchers have evaluated the efficiency of CBCT when it comes to identifying MB2 canals, and CBCT has been suggested to be a reliable method for the detection of these canals. However, in clinically relevant situations, such a smaller lesions on root-filled teeth, CBCT accuracy is greatly reduced (sensitivity 0.63, specificity 0.69) . Moreover, clinician dependent interpretation of CBCT imaging still suffers from low inter- and intra-observer agreement.

Computer-aided detection and diagnosis (CAD) has been widely applied to biomedical image analysis outside of dentistry .

Study Design

Study Type:
Observational
Anticipated Enrollment :
50 participants
Observational Model:
Other
Time Perspective:
Other
Official Title:
The Accuracy of Computer Aided Detection of Second Mesio-buccal Canal of Maxillary First Molars on CBCT Images Using Deep Learning Model (Artificial Intelligence): Diagnostic Accuracy Study
Anticipated Study Start Date :
May 1, 2022
Anticipated Primary Completion Date :
Sep 1, 2023
Anticipated Study Completion Date :
Oct 1, 2023

Arms and Interventions

Arm Intervention/Treatment
CBCT Images of Maxillary 1st molars

Diagnostic Test: deep learning model
deep learning model developed by computer science expert and based on convolution neural network , and trained by our datasets.
Other Names:
  • artificial intelligence tool
  • Outcome Measures

    Primary Outcome Measures

    1. accuracy of detection of MB2 [baseline]

      detection of MB2 on CBCT images of maxillary first molars using deep learning model

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • • CBCT scans showing erupted maxillary 1st molar.

    • Vovel size not exceeding 0.1mm.

    • Maxillary molars showing complete root formation.

    • Carious or Non-carious tooth.

    Exclusion Criteria:
    • • Maxillary first molars with developmental anomalies, external or internal root resorption, root canal calcification, previous root canal treatment, post restorations, and/or root caries.

    • CBCT images of sub-optimal quality or artifacts / high scatter interfering with proper assessment.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Faculty of dentistry cairo university Cairo Egypt 12611

    Sponsors and Collaborators

    • Cairo University

    Investigators

    • Study Director: Enas Anter, Ph.D, Cairo University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    Responsible Party:
    Arwa Mousa, lecturer of oral and maxillofacial radiology, faculty of dentistry, Cairo University
    ClinicalTrials.gov Identifier:
    NCT05340140
    Other Study ID Numbers:
    • CBCT AI 7-1-1
    First Posted:
    Apr 21, 2022
    Last Update Posted:
    Apr 21, 2022
    Last Verified:
    Apr 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No

    Study Results

    No Results Posted as of Apr 21, 2022