Accuracy of Scoring Systems for Risk Assessment in Neonatal Intensive Care Unit
Study Details
Study Description
Brief Summary
Early detection of neonates with higher risk of death is quite important for paying more attention to these cases, timely referral to tertiary neonatal intensive care unit (NICU), and provision of meticulous critical care, which ultimately may improve outcomes. Several scoring systems have recently been developed for assessment of the intensity of illness and prognosticate the risk of not only neonatal mortality but also short- and long-term morbidities. The accuracy of these scoring systems has been investigated in several NICUs from different countries, such as USA, UK, Canada, Brazil, India, and Iran. Previous Egyptian studies have investigated the accuracy of Clinical Risk Index for Babies II (CRIB II), Score for Neonatal Acute Physiology II (SNAP-II) and its Perinatal Extension II (SNAPPE-II). However, the accuracy of Sensorium, temperature, oxygenation, perfusion, skin color, and blood sugar (STOPS), Modified Sick neonatal Score (MSNS), and neonatal sequential organ failure assessment (nSOFA) has not been investigated in Egyptian NICUs. Therefore, more studies are required to investigate the utility and accuracy of neonatal risk assessment scores in Egyptian NICUs.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Study participants Neonates admitted to NICU and fulfilling eligibility criteria |
Other: CRIB II
Calculate Clinical Risk Index for Babies II score
Other: SNAP-II
Calculate Score for Neonatal Acute Physiology II
Other: SNAPPE-II
Calculate Score for Neonatal Acute Physiology Perinatal Extension II
Other: STOPS
Calculate Sensorium, temperature, oxygenation, perfusion, skin color, and blood sugar score
Other: MSNS
Calculate Modified Sick neonatal Score
Other: nSOFA
Calculate neonatal sequential organ failure assessment
|
Outcome Measures
Primary Outcome Measures
- Survival at discharge [One year]
Proportion of neonates discharged alive from NICU
Secondary Outcome Measures
- Length of hospital stay [One year]
Length of stay in NICU
- Need for CPAP [One year]
Proportion of neonates connected to continuous positive airway pressure
- Need for invasive ventilation [One year]
Proportion of neonates requiring invasive ventilation
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Admission within 24 hours after birth.
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Length of hospital stay at the first admission to NICU ≥12 hours
Exclusion Criteria:
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Major congenital anomalies.
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Discharge against medical advice
-
Transportation to other places.
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Missing data on items of scoring systems
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Neonatal Intensive Care Units at Sohag University Hospitals | Sohag | Egypt | 82524 |
Sponsors and Collaborators
- Sohag University
Investigators
- Study Chair: Montaser M Mohamed, MD, PhD, Sohag University
Study Documents (Full-Text)
None provided.More Information
Publications
- Ezz-Eldin ZM, Hamid TA, Youssef MR, Nabil Hel-D. Clinical Risk Index for Babies (CRIB II) Scoring System in Prediction of Mortality in Premature Babies. J Clin Diagn Res. 2015 Jun;9(6):SC08-11. doi: 10.7860/JCDR/2015/12248.6012. Epub 2015 Jun 1.
- Garg B, Sharma D, Farahbakhsh N. Assessment of sickness severity of illness in neonates: review of various neonatal illness scoring systems. J Matern Fetal Neonatal Med. 2018 May;31(10):1373-1380. doi: 10.1080/14767058.2017.1315665. Epub 2017 Apr 20.
- Mansoor KP, Ravikiran SR, Kulkarni V, Baliga K, Rao S, Bhat KG, Baliga BS, Kamath N. Modified Sick Neonatal Score (MSNS): A Novel Neonatal Disease Severity Scoring System for Resource-Limited Settings. Crit Care Res Pract. 2019 May 9;2019:9059073. doi: 10.1155/2019/9059073. eCollection 2019.
- Parry G, Tucker J, Tarnow-Mordi W; UK Neonatal Staffing Study Collaborative Group. CRIB II: an update of the clinical risk index for babies score. Lancet. 2003 May 24;361(9371):1789-91. doi: 10.1016/S0140-6736(03)13397-1.
- Richardson DK, Corcoran JD, Escobar GJ, Lee SK. SNAP-II and SNAPPE-II: Simplified newborn illness severity and mortality risk scores. J Pediatr. 2001 Jan;138(1):92-100. doi: 10.1067/mpd.2001.109608.
- Vardhelli V, Murki S, Tandur B, Saha B, Oleti TP, Deshabhotla S, Mohammed YA, Seth S, Siramshetty S, Kallem VR. Comparison of CRIB-II with SNAPPE-II for predicting survival and morbidities before hospital discharge in neonates with gestation </= 32 weeks: a prospective multicentric observational study. Eur J Pediatr. 2022 Jul;181(7):2831-2838. doi: 10.1007/s00431-022-04463-2. Epub 2022 May 6.
- Vardhelli V, Seth S, Mohammed YA, Murki S, Tandur B, Saha B, Oleti TP, Deshabhotla S, Siramshetty S, Kallem VR. Comparison of STOPS and SNAPPE-II in Predicting Neonatal Survival at Hospital Discharge: A Prospective, Multicentric, Observational Study. Indian J Pediatr. 2022 Sep 22. doi: 10.1007/s12098-022-04330-w. Online ahead of print.
- Wynn JL, Polin RA. A neonatal sequential organ failure assessment score predicts mortality to late-onset sepsis in preterm very low birth weight infants. Pediatr Res. 2020 Jul;88(1):85-90. doi: 10.1038/s41390-019-0517-2. Epub 2019 Aug 8.
- Soh-Med-23-03-10MS