Nano Fat Injection With or Without Fractional Carbon Dioxide Laser in Acne Scars
Study Details
Study Description
Brief Summary
Assessment of nano fat grafting combined with carbon dioxide laser resurfacing versus nano fat grafting alone in treating facial atrophic acne scars
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Acne scars is a world wide problem .though lots of treatment exists still mo gold standard for treatment of acne scars in this study.
Assessment of nano fat grafting combined with carbon dioxide laser resurfacing versus nano fat grafting alone in treating facial atrophic acne scars
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Nano fat grafting and fractional carbon dioxide laser resurfacing treating of atrophic acne scars with nano fat and fractional carbon dioxide laser |
Procedure: Fat grafting
Nano fat grafting followed by fractional carbon dioxide laser resurfacing
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Clinical assessment of acne scar severity [up to 24 weeks]
as assessed using the Goodman and Baron Qualitative scar grading system before and after treatment on both sides of face, to determine the number of patients achieving two grades improvement vs one grade or no improvement
Secondary Outcome Measures
- Physician global assessment [up to 24 weeks]
two blinded observers will compare the before and after photographs separately on each facial side and will evaluate the improvement on a quartile grading scale as: poor,<25% improvement; fair, 25%-50% improvement; good, 51%-75% improvement; and excellent, >75% improvement.
- percent of reduction in scar count [up to 24 weeks]
count of the total and different types of acne scars was performed, before and after treatment on both sides of the face, and the percent of reduction was calculated
- Patient satisfaction [1 year]
Patients will rate their overall satisfaction on a quartile grading system: 0, unsatisfied; 1, slightly satisfied; 2, satisfied; and 3, very satisfied
- Adverse events [1 year]
erythema, edema, crusting, pigmentary changes, ecchymosis, and scarring, will be recorded
Eligibility Criteria
Criteria
Inclusion Criteria:
- patients older than 18 years who attend the Outpatient Clinics of Dermatology and Plastic Surgery Departments, Assiut University Hospital, with moderate to severe atrophic facial acne scars on both cheeks, as assessed using the Goodman and Baron Qualitative scar grading system (12), will be enrolled in the study.
Exclusion Criteria:
- include: pregnancy or lactation; active acne, history of deep chemical peeling or filler injection in the previous 6 months, history of keloid or hypertrophic scar formation; use of isotretinoin in the previous 6 months; active infection in the treatment area; bleeding tendencies; history of herpes simplex or herpes zoster infection on the face; and patients with unrealistic expectations.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Faculty of Medicine, Assiut University | Assiut | Egypt | 71111 |
Sponsors and Collaborators
- Assiut University
Investigators
- Principal Investigator: youssef S farrag, MD, Department of Plastic Surgery, professor
- Principal Investigator: Wael S Ibraheem, MD, Department of Plastic Surgery , Assistant lecture
Study Documents (Full-Text)
None provided.More Information
Publications
- nano fat injection