LIBREXIA-ACS: A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Sponsor
Janssen Research & Development, LLC (Industry)
Overall Status
Not yet recruiting
CT.gov ID
NCT05754957
Collaborator
(none)
16,000
863
2
43.4
18.5
0.4
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate that milvexian is superior to placebo, in addition to standard-of-care, in reducing the risk of major adverse cardiovascular event (MACE) (the composite of cardiovascular [CV] death, myocardial infarction [MI], and ischemic stroke).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 3 |
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
16000 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose:
Treatment
Official Title:
A Phase 3, Randomized, Double-blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, After a Recent Acute Coronary Syndrome
Anticipated Study Start Date
:
Mar 8, 2023
Anticipated Primary Completion Date
:
Sep 7, 2026
Anticipated Study Completion Date
:
Oct 19, 2026
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Milvexian Participants enrolled within 7 days of an acute coronary syndrome (ACS), who have undergone cardiac catheterization with percutaneous intervention (PCI) or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (single antiplatelet therapy [SAPT] or dual antiplatelet therapy [DAPT]) as determined by the investigator will receive milvexian orally. |
Drug: Milvexian
Milvexian will be administered orally.
Other Names:
|
| Placebo Comparator: Placebo Participants enrolled within 7 days of an ACS, who have undergone cardiac catheterization with PCI or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (SAPT or DAPT) as determined by the investigator will receive placebo orally. |
Other: Placebo
Placebo will be administered orally.
|
Outcome Measures
Primary Outcome Measures
- Time to First Occurrence of Major Adverse Cardiovascular Event (MACE) [Up to 3 years 6 months]
Time to first occurrence of any component of MACE will be reported. MACE is a composite of cardiovascular (CV) death, myocardial infarction (MI), and ischemic stroke.
Secondary Outcome Measures
- Time to the First Occurrence of Major Adverse Vascular Event (MAVE) [Up to 3 years 6 months]
Time to first occurrence of any component of MAVE will be reported. MAVE is a composite of CV death, MI, ischemic stroke, major adverse limb event (MALE), and symptomatic venous thromboembolism (VTE).
- Time to the First Occurrence of Composite of All-cause Mortality (ACM), Myocardial Infarction (MI) and Ischemic Stroke [Up to 3 years 6 months]
Time to the first occurrence of composite of ACM, MI and ischemic stroke will be reported.
- Time to Cardiovascular (CV) Death [Up to 3 years 6 months]
Time to CV death will be reported.
- Time to All-cause Mortality (ACM) [Up to 3 years 6 months]
Time to ACM will reported. ACM will be categorized into CV death, non-CV death, and death due to unknown cause.
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Participants must have an index event that meets all 3 of the following criteria within 7 days prior to randomization: a) clinical syndrome consistent with spontaneous cardiac ischemia, b) diagnosis of acute coronary syndrome (ACS) (that is, ST-elevation myocardial infarction [STEMI], non-STEMI, or unstable angina [UA]), c) cardiac biomarker elevation (example, troponin I, troponin T, creatine kinase-MB [CK-MB]) above the upper limit of normal as determined by the local laboratory
-
Participants must have at least 2 of the following risk factors:a) age 65 or older, b) diabetes mellitus, c) history of a prior myocardial infarction (MI) (other than index ACS event), d) multivessel coronary artery disease (CAD), e) history of coronary artery bypass graft (CABG) surgery prior to index ACS event, f) history of peripheral artery disease (PAD) or cerebrovascular disease (example, carotid atherosclerosis, intracranial artery stenosis, g) conservative management (that is, no percutaneous intervention [PCI] or CABG after index ACS event), h) Any one or more of the following high-risk angiographic features i) total stent length of greater than (>) 30 millimeters (mm), ii) thrombotic target lesion, iii) bifurcation lesion treated with more than one stent, iv) calcified target lesion treated with atherectomy, v) treatment of obstructive left main or proximal left anterior descending artery for index ACS (or clinical diagnosis of an anterior STEMI)
-
All female participants of childbearing potential must have a negative highly sensitive serum beta-human chorionic gonadotropin (hCG) or urine test at screening
-
A female participant must not be pregnant, breastfeeding, or planning to become pregnant until 4 days (5 half-lives) after the last dose of study intervention
Exclusion Criteria:
-
MI secondary to ischemia due to either increased oxygen demand or decreased supply (Type 2 MI) or periprocedural MI as the index ACS event
-
Planned CABG or staged PCI after randomization
-
Any condition that requires chronic anticoagulation at the discretion of the investigator and/or local guidelines
-
Conditions with a significant increased risk of bleeding (example, clinically significant bleeding within previous 3 months, known bleeding diathesis, et cetera)
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Advanced Cardiovascular, LLC | Alexander City | Alabama | United States | 35010 |
| 2 | Ascension St. Vincent's Health System | Birmingham | Alabama | United States | 35205 |
| 3 | HH Heart Center and Heart Center | Huntsville | Alabama | United States | 35801 |
| 4 | Mobile Heart Specialists, PC | Mobile | Alabama | United States | 36608 |
| 5 | Mercy Gilbert Medical Center | Gilbert | Arizona | United States | 85297 |
| 6 | Maricopa Medical Center | Phoenix | Arizona | United States | 85008 |
| 7 | HonorHealth Neurology | Scottsdale | Arizona | United States | 85258 |
| 8 | Pima Heart and Vascular | Tucson | Arizona | United States | 85704 |
| 9 | Bakersfield Memorial Hospital | Bakersfield | California | United States | 93306 |
| 10 | Mission Cardiovascular Research Institute | Fremont | California | United States | 94538 |
| 11 | University of California at San Diego | La Jolla | California | United States | 92093 |
| 12 | Radin Cardiovascular Medical Group | Newport Beach | California | United States | 92663 |
| 13 | Valley Clinical Trials, Inc. | Northridge | California | United States | 91325 |
| 14 | Stanford University School of Medicine | Palo Alto | California | United States | 94304 |
| 15 | Sharp HealthCare | San Diego | California | United States | 92123 |
| 16 | UCLA | Santa Monica | California | United States | 90401 |
| 17 | Ramin Manshadi, MD | Stockton | California | United States | 95204 |
| 18 | South Denver Cardiology Associates PC | Littleton | Colorado | United States | 80120 |
| 19 | Cardiology Associates of Fairfield County, P.C. | Stamford | Connecticut | United States | 06905 |
| 20 | PriMed Physicians, A Member of NE Medical Group | Trumbull | Connecticut | United States | 06611 |
| 21 | Integrative Research Associates | Fort Lauderdale | Florida | United States | 33312 |
| 22 | Shands Jacksonville Medical Center - University of Florida | Jacksonville | Florida | United States | 32209 |
| 23 | Cardiology Partners Clinical Research Institute | Loxahatchee Groves | Florida | United States | 33470 |
| 24 | ARS - DeLand Clinical Research Unit | Orange | Florida | United States | 32763 |
| 25 | Beneva Cardiology | Sarasota | Florida | United States | 34232 |
| 26 | Cardiovascular Center of Sarasota | Sarasota | Florida | United States | 34239 |
| 27 | Grady Memorial Hospital | Atlanta | Georgia | United States | 30303 |
| 28 | Atlanta Clinical Research Center | Cartersville | Georgia | United States | 30121 |
| 29 | Northeast Georgia Heart Center | Gainesville | Georgia | United States | 30501-3715 |
| 30 | Jesse Brown VAMC Department of Surgery | Chicago | Illinois | United States | 60612 |
| 31 | Chicago Medical Research, LLC | Hazel Crest | Illinois | United States | 60429 |
| 32 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
| 33 | Prairie Cardiovascular Consultants, Ltd. | Springfield | Illinois | United States | 62701 |
| 34 | Midwest Cardiovascular Research Foundation | Elkhart | Indiana | United States | 46514-2487 |
| 35 | Parkview Research Center | Fort Wayne | Indiana | United States | 46845 |
| 36 | IU Health Ball Memorial Hospital | Muncie | Indiana | United States | 47303 |
| 37 | Cardiovascular Research of Northwest Indiana | Munster | Indiana | United States | 46321 |
| 38 | Reid Health | Richmond | Indiana | United States | 47374 |
| 39 | Cambridge Medical Trials | Alexandria | Louisiana | United States | 71301 |
| 40 | Grace Research, LLC | Shreveport | Louisiana | United States | 71105 |
| 41 | Louisiana Heart Center | Slidell | Louisiana | United States | 70458 |
| 42 | Eastern Maine Medical Center Northeast Cardiology Associates | Bangor | Maine | United States | 04401 |
| 43 | Johns Hopkins University School of Medicine | Baltimore | Maryland | United States | 21231 |
| 44 | Suburban Hospital | Bethesda | Maryland | United States | 20814 |
| 45 | Tidal Health Peninsula Regional Inc. | Salisbury | Maryland | United States | 21801 |
| 46 | Pentucket Medical Associates | Haverhill | Massachusetts | United States | 01830 |
| 47 | Mclaren Bay Region | Bay City | Michigan | United States | 48708 |
| 48 | Genesys Regional Medical Center | Grand Blanc | Michigan | United States | 48439 |
| 49 | Ascension Providence Hospital | Saginaw | Michigan | United States | 48075 |
| 50 | St Marys Medical Center | Saginaw | Michigan | United States | 48601 |
| 51 | St. Luke's Speciality Clinic | Duluth | Minnesota | United States | 55802-2207 |
| 52 | Cardiology Associates of North Mississippi | Tupelo | Mississippi | United States | 38801 |
| 53 | North Kansas City Hospital | Kansas City | Missouri | United States | 64116 |
| 54 | Spectrum Clinical Research | Kansas City | Missouri | United States | 64118 |
| 55 | Saint Louis University | Saint Louis | Missouri | United States | 63110 |
| 56 | Bryan LGH Heart Institute | Lincoln | Nebraska | United States | 68506 |
| 57 | Methodist Physicians Clinic Heart Consultants | Omaha | Nebraska | United States | 68114 |
| 58 | Advanced Heart Care, LLC | Bridgewater | New Jersey | United States | 08807 |
| 59 | Cardiac Care & Vascular Medicine, PLLC | Bronx | New York | United States | 10469 |
| 60 | Columbia University Medical Center | New York | New York | United States | 10032 |
| 61 | Hudson Valley Cardiovascular Practice, PC | Poughkeepsie | New York | United States | 12601 |
| 62 | Westchester Medical Center | Valhalla | New York | United States | 10532 |
| 63 | UNC School of Medicine | Chapel Hill | North Carolina | United States | 27599-5021 |
| 64 | Clinical Trials of America | Lenoir | North Carolina | United States | 28645 |
| 65 | Rex Hospital | Raleigh | North Carolina | United States | 27607 |
| 66 | Sanford Cardiology | Sanford | North Carolina | United States | 27330 |
| 67 | Summa Health System | Akron | Ohio | United States | 44304 |
| 68 | Kettering Medical Center | Kettering | Ohio | United States | 45429 |
| 69 | University of Toledo | Toledo | Ohio | United States | 43614-2598 |
| 70 | Ascension Medical Group - St. John Clinic Infectious Disease | Bartlesville | Oklahoma | United States | 74006 |
| 71 | South Oklahoma Heart Research | Oklahoma City | Oklahoma | United States | 73135 |
| 72 | St John Health System Inc | Tulsa | Oklahoma | United States | 74104 |
| 73 | Hamot Medical Center | Erie | Pennsylvania | United States | 16507 |
| 74 | AnMed Health | Anderson | South Carolina | United States | 29621 |
| 75 | St. Francis Physician Services, Inc, DBA Upstate Cardiology Research | Greenville | South Carolina | United States | 29607 |
| 76 | Carolina Cardiology Associates | Rock Hill | South Carolina | United States | 29732 |
| 77 | Monument Health Clinical Research | Rapid City | South Dakota | United States | 57701 |
| 78 | Apex Cardiology | Jackson | Tennessee | United States | 38301 |
| 79 | Tennessee Oncology | Nashville | Tennessee | United States | 37205 |
| 80 | Amarillo Heart Clinical Research Institute | Amarillo | Texas | United States | 79106 |
| 81 | PharmaTex Research | Amarillo | Texas | United States | 79109 |
| 82 | Texas Tech University Health Sciences Center - El Paso | El Paso | Texas | United States | 79905 |
| 83 | East Texas Cardiology, PA | Houston | Texas | United States | 77002 |
| 84 | Texas Cardiology Research Center | Kingwood | Texas | United States | 77339 |
| 85 | Ascension Texas Cardiovascular | Kyle | Texas | United States | 78640 |
| 86 | University Cardiology Group | Lubbock | Texas | United States | 79415 |
| 87 | Revival Research Institute, LLC | Sherman | Texas | United States | 75092 |
| 88 | University of Virginia | Leesburg | Virginia | United States | 20176 |
| 89 | MultiCare Health System | Tacoma | Washington | United States | 98405 |
| 90 | Mayo Clinic Health System | La Crosse | Wisconsin | United States | 54601-4795 |
| 91 | Hospital Interzonal General de Agudos Dr. Jose Penna | Bahia Blanca | Argentina | B8001DDU | |
| 92 | Hospital Italiano Regional Del Sur | Bahia Blanca | Argentina | B8001HXM | |
| 93 | Sanatorio Finochietto | Buenos Aires | Argentina | C1187AAN | |
| 94 | Sanatorio Guemes | Caba | Argentina | C1180AAX | |
| 95 | Centro Medico Dra. Laura Maffei - Investigacion Clinica Aplicada | Ciudad Autonoma Buenos Aires | Argentina | 1425 | |
| 96 | Instituto Cardiovascular de Buenos Aires | Ciudad Autonoma Buenos Aires | Argentina | 1428 | |
| 97 | Fundacion Favaloro | Ciudad Autonoma Buenos Aires | Argentina | C1093AAS | |
| 98 | Clínica Adventista Belgrano | Ciudad Autonoma Buenos Aires | Argentina | C1430EGF | |
| 99 | Clínica y Maternidad Suizo Argentina | Ciudad Autonoma de Buenos Aires | Argentina | 1118 | |
| 100 | Hospital Italiano de Buenos Aires | Ciudad Autonoma de Buenos Aires | Argentina | C1181ACH | |
| 101 | Hospital Britanico de Buenos Aires | Ciudad Autonoma de Buenos Aires | Argentina | C1280AEB | |
| 102 | Clínica Chutro | Cordoba | Argentina | 5000 | |
| 103 | Hospital San Roque | Cordoba | Argentina | 5000 | |
| 104 | Sanatorio Duarte Quiroz | Cordoba | Argentina | 5000 | |
| 105 | Clinica Romagosa | Cordoba | Argentina | X5000AAI | |
| 106 | Sanatorio Allende | Cordoba | Argentina | X5000JHQ | |
| 107 | Sanatorio de la Canada | Cordoba | Argentina | X5000 | |
| 108 | Instituto Privado De Especialidades Medicas S.A. Fundacion J Robert Cade | Cordoba | Argentina | X5002HWE | |
| 109 | Hospital Cordoba | Cordoba | Argentina | X5004CDT | |
| 110 | Centro Medico Luquez | Cordoba | Argentina | X5006IKK | |
| 111 | Hospital Privado Centro Medico de Cordoba | Cordoba | Argentina | X5016KEH | |
| 112 | Clinica Coronel Suarez | Coronel Suarez | Argentina | B7540GHD | |
| 113 | Hospital El Cruce | Florencio Varela | Argentina | B1888AAE | |
| 114 | Centro Medico Lebensohn | Junin | Argentina | B6000BHA | |
| 115 | Hospital Italiano de La Plata | La Plata | Argentina | B1900AXI | |
| 116 | Centro de Investigaciones Medicas Mar Del Plata | Mar del Plata | Argentina | B7600FYK | |
| 117 | Sanatorio Modelo de Quilmes | Quilmes | Argentina | B1878DKF | |
| 118 | Instituto Cardiovascular de Rosario | Rosario | Argentina | S2000DSR | |
| 119 | Sanatorio Parque | Rosario | Argentina | S2000SDV | |
| 120 | Hospital Italiano Garibaldi | Rosario | Argentina | S2001ODA | |
| 121 | Hospital Provincial del Centenario | Rosario | Argentina | S2002KDS | |
| 122 | Centro de Investigaciones Clinicas Salta | Salta | Argentina | 4400 | |
| 123 | Centro Cardiovascular Salta | Salta | Argentina | 4406 | |
| 124 | Cordis S A | Salta | Argentina | A4400ANW | |
| 125 | Corporacion Medica de Gral. San Martin S.A. | San Martin | Argentina | 1650 | |
| 126 | Investigaciones Clinicas Tucuman | San Miguel de Tucuman | Argentina | T4000ICL | |
| 127 | Estudios Clinicos de los Arroyos | San Nicolas | Argentina | 2900 | |
| 128 | Sanatorio Mayo SA | Santa Fe | Argentina | S3000AZH | |
| 129 | Hospital José María Cullen | Santa Fe | Argentina | S3000EOZ | |
| 130 | Sanatorio Medico de Diagnostico y Tratamiento | Santa Fe | Argentina | S3000FUJ | |
| 131 | Sanatorio San Martin | Venado Tuerto | Argentina | S2600KUE | |
| 132 | Clinica Privada Fusavim SRL | Villa Maria | Argentina | X5900JKA | |
| 133 | Royal Adelaide Hospital | Adelaide | Australia | 5000 | |
| 134 | Flinders Medical Centre | Adelaide | Australia | 5042 | |
| 135 | Ballarat Base Hospital | Ballarat | Australia | 3350 | |
| 136 | Cairns Base Hospital | Cairns | Australia | 4870 | |
| 137 | Royal Prince Alfred Hospital | Camperdown | Australia | 2050 | |
| 138 | Monash Medical Centre | Clayton | Australia | 3168 | |
| 139 | Concord Repatriation General Hospital | Concord | Australia | 2139 | |
| 140 | Lyell McEwin Hospital | Elizabeth Vale | Australia | 5112 | |
| 141 | Royal Brisbane and Women's Hospital | Herston | Australia | 4029 | |
| 142 | Royal Hobart Hospital | Hobart | Australia | 7000 | |
| 143 | Nepean Hospital | Kingswood | Australia | 2747 | |
| 144 | Core Research Group | Milton | Australia | 4064 | |
| 145 | Fiona Stanley Hospital | Murdoch | Australia | 6150 | |
| 146 | Gold Coast University Hospital | Southport | Australia | 4215 | |
| 147 | Wollongong Hospital | Wollongong | Australia | 2500 | |
| 148 | The Queen Elizabeth Hospital | Woodville South | Australia | 5011 | |
| 149 | Klinik Floridsdorf | Austria | Austria | 1210 | |
| 150 | KH St.Josef Braunau am Inn | Braunau am Inn | Austria | 5280 | |
| 151 | Landeskrankenhaus Feldkirch | Feldkirch | Austria | A-6807 | |
| 152 | LKH-Univ. Klinikum Graz | Graz | Austria | 8036 | |
| 153 | Medizinische Universität Innsbruck | Innsbruck | Austria | 6020 | |
| 154 | Krankenhaus der Elisabethinen Linz | Linz | Austria | 4020 | |
| 155 | Wilhelminenspital der Stadt Wien | Vienna | Austria | 1160 | |
| 156 | KH Wiener Neustadt | Wiener Neustadt | Austria | 2700 | |
| 157 | AKH - Medizinische Universität Wien | Wien | Austria | 1090 | |
| 158 | Imeldaziekenhuis | Bonheiden | Belgium | 2820 | |
| 159 | AZ Klina | Brasschaat | Belgium | 2930 | |
| 160 | AZ Sint-Jan | Brugge | Belgium | 8000 | |
| 161 | Universitair Ziekenhuis Brussel | Brussels | Belgium | 1090 | |
| 162 | C.H.U. Brugmann | Bruxelles | Belgium | 1020 | |
| 163 | Cliniques Universitaires Saint-Luc | Bruxelles | Belgium | 1200 | |
| 164 | UZA | Edegem | Belgium | 2650 | |
| 165 | Ziekenhuis Oost-Limburg | Genk | Belgium | 3600 | |
| 166 | AZ Sint-Lucas | Gent | Belgium | 9000 | |
| 167 | Jessa Ziekenhuis | Hasselt | Belgium | 3500 | |
| 168 | CHR de la Citadelle | Liege | Belgium | 4000 | |
| 169 | CHU de Liège | Liège | Belgium | 4000 | |
| 170 | Az Sint-Maarten | Mechelen | Belgium | 97770 | |
| 171 | Heilig Hart Ziekenhuis Lier | Mol | Belgium | 2400 | |
| 172 | AZ Delta | Roeselare | Belgium | 8800 | |
| 173 | AZ Turnhout | Turnhout | Belgium | 2300 | |
| 174 | Hospital Vera Cruz | Belo Horizonte | Brazil | 30140-062 | |
| 175 | Hospital Universitário Ciencias Medicas | Belo Horizonte | Brazil | 30140-073 | |
| 176 | Cardresearch - Cardiologia Assistencial | Belo Horizonte | Brazil | 30150-240 | |
| 177 | Instituto das Pequenas Missionárias de Maria Imaculada - Hospital Madre Teresa | Belo Horizonte | Brazil | 30380-090 | |
| 178 | UNESP - Faculdade de Medicina da Universidade Estadual Paulista - Campus Botucatu | Botucatu | Brazil | 18618-686 | |
| 179 | Centro de Cardiologia Clinica e Pesquisa Doutora Juliana Souza Ltda. - CECAP Centro de Cardiologia Clinica | Brasilia | Brazil | 70710-149 | |
| 180 | Hospital do Coração do Brasil | Brasília | Brazil | 70390903 | |
| 181 | Sociedade Hospitalar Angelina Caron | Campina Grande Do Sul | Brazil | 83430-000 | |
| 182 | C.E.C. - Centro Especializado em Cardiologia Ltda. - Loema Medicina e Bem Estar | Campinas | Brazil | 13010-001 | |
| 183 | Instituto de Pesquisa Clinica de Campinas | Campinas | Brazil | 13060-080 | |
| 184 | Sociedade Literaria e Caritativa Santo Agostinho - Hospital Sao Jose | Criciúma | Brazil | 88811-508 | |
| 185 | Irmandade Santa Casa de Misericórdia de Curitiba | Curitiba | Brazil | 80010-030 | |
| 186 | Associacao Paranaense de Cultura - PUCPR | Curitiba | Brazil | 80230-130 | |
| 187 | Hospital Cardiológico Costantini | Curitiba | Brazil | 80320-320 | |
| 188 | Hospital Das Clinicas Da Universidade Federal De Goias | Goiania | Brazil | 74605-020 | |
| 189 | Instituto do Coracao de Marília | Marilia | Brazil | 17515-000 | |
| 190 | Hemocardio SS Ltda | Natal | Brazil | 59020-035 | |
| 191 | Instituto Mederi de Pesquisa e Saude | Passo Fundo | Brazil | 99010-120 | |
| 192 | Santa Casa de Misericórdia de Pelotas | Pelotas | Brazil | 96015-290 | |
| 193 | Associação Hospitalar Moinhos de Vento | Porto Alegre | Brazil | 90035-001 | |
| 194 | Hospital das Clinicas de Porto Alegre | Porto Alegre | Brazil | 90035-903 | |
| 195 | IMV-Pesquisa Cardiologica Sociedade Simples - HMD - COR l | Porto Alegre | Brazil | 90110-270 | |
| 196 | Hospital Ernesto Dornelles | Porto Alegre | Brazil | 90160-092 | |
| 197 | União Brasileira de Educação e Assistência-Hospital São Lucas da PUCRS | Porto Alegre | Brazil | 90610-000 | |
| 198 | Fundacao Universitaria de Cardiologia | Porto Alegre | Brazil | 90620-001 | |
| 199 | Hospital Nossa Senhora da Conceicao S.A | Porto Alegre | Brazil | 91350-200 | |
| 200 | PROCAPE - Universidade de Pernambuco Pronto Socorro Cardiológico de Pernambuco prof Luiz Tavares | Recife | Brazil | 50100-060 | |
| 201 | Secretaria de Saude - Hospital Agamenon Magalhaes | Recife | Brazil | 52051-380 | |
| 202 | Hospital das Clínicas da Faculdade de Medicina de RPUSP - HCRP | Ribeirao Preto | Brazil | 14098-900 | |
| 203 | Hospital sao lucas | Rio de Janeiro | Brazil | 22061-080 | |
| 204 | Hospital Santa Izabel - Santa Casa de Misericórdia da Bahia | Salvador | Brazil | 40050-410 | |
| 205 | Instituto CardioPulmonar | Salvador | Brazil | 40170310 | |
| 206 | Fundação Bahiana de Cardiologia | Salvador | Brazil | 41810-010 | |
| 207 | Hospital da Bahia | Salvador | Brazil | 41810011 | |
| 208 | Pesquisare Saude | Santo André | Brazil | 09080-110 | |
| 209 | CEMEC - Centro Multidisciplinar de Estudos Clínicos | Sao Bernardo Do Campo | Brazil | 09715-090 | |
| 210 | Fundação Faculdade Regional de Medicina de São José do Rio Preto - Hospital de Base | Sao Jose do Rio Preto | Brazil | 15090-000 | |
| 211 | FGM Clínica Paulista de Doenças Cardiovasculares Ltda. | Sao Paulo | Brazil | 01323-000 | |
| 212 | Hospital Alemão Oswaldo Cruz | Sao Paulo | Brazil | 01323-903 | |
| 213 | Instituto Dante Pazzanese de Cardiologia | Sao Paulo | Brazil | 04012-909 | |
| 214 | Hospital Das Clinicas Da Faculdade De Medicina Da USP | Sao Paulo | Brazil | 05403-000 | |
| 215 | Casa de Saúde Santa Marcelina - Hospital Santa Marcelina | Sao Paulo | Brazil | 08270-120 | |
| 216 | Instituto de Molestias Cardiovasculares | São Jose do Rio Preto | Brazil | 15015-210 | |
| 217 | Instituto de Cardiologia de Santa Catarina | São José | Brazil | 88103-460 | |
| 218 | Irmandade Da Santa Casa de Misericordia de Sao Paulo | São Paulo | Brazil | 01221-020 | |
| 219 | Real e Benemérita Associação Portuguesa de Beneficência | São Paulo | Brazil | 01323-900 | |
| 220 | Instituto de Moléstias Cardiovasculares Tatuí | Tatuí | Brazil | 18270-170 | |
| 221 | HC-UFTM - Hospital de Clínicas da Universidade Federal do Triângulo Mineiro | Uberaba | Brazil | 38025-350 | |
| 222 | Clínica Cardioped Ltda | Vitória | Brazil | 29702-020 | |
| 223 | CEDOES | Vitória | Brazil | Espírito Santo | |
| 224 | Santa Casa de Misericórdia de Votuporanga | Votuporanga | Brazil | 15500-003 | |
| 225 | MHAT Puls | Blagoevgrad | Bulgaria | 2700 | |
| 226 | MHAT Heart and Brain | Burgas | Bulgaria | 8000 | |
| 227 | Multiprofile Hospital for Active Treatment Dr. Tota Venkova | Gabrovo | Bulgaria | 5300 | |
| 228 | Multiprofile Hospital for Active Treatment - Haskovo | Haskovo | Bulgaria | 6300 | |
| 229 | MHAT Uni Hospital | Panagyurishte | Bulgaria | 4500 | |
| 230 | SHATC Sveti Georgi-Pernik OOD | Pernik | Bulgaria | 2300 | |
| 231 | Multiprofile Hospital for Active Treatment Heart and Brain, Pleven | Pleven | Bulgaria | 5800 | |
| 232 | UMHAT 'Dr. Georgi Stranski', EAD | Pleven | Bulgaria | 5800 | |
| 233 | UMHAT 'Sv. Georgi' EAD | Plovdiv | Bulgaria | 4002 | |
| 234 | MHAT Sv. Karidad EAD | Plovdiv | Bulgaria | 4004 | |
| 235 | 2th MHAT - Sofia | Sofia | Bulgaria | 1202 | |
| 236 | National Heart Hospital | Sofia | Bulgaria | 1309 | |
| 237 | Diagnostic Consultation Centre 'Alexandrovska' EOOD | Sofia | Bulgaria | 1431 | |
| 238 | UMHAT Prof. Dr. Aleksandar Chirkov | Sofia | Bulgaria | 1431 | |
| 239 | University Multiprofile Hospital for Active Treatment - Tsaritsa Yoanna - ISUL, EAD | Sofia | Bulgaria | 1527 | |
| 240 | UMHATEM N I Pirogov | Sofia | Bulgaria | 1606 | |
| 241 | University Multiprofile Hospital for Active Treatment- UMHAT Sveta Anna AD | Sofia | Bulgaria | 1750 | |
| 242 | UMHAT Sofia Med | Sofia | Bulgaria | 1797 | |
| 243 | UMHAT Prof. Dr. St. Kirkovich AD | Stara Zagora | Bulgaria | 6003 | |
| 244 | Foothills Hospital | Calgary | Alberta | Canada | T2N4N2 |
| 245 | University of Alberta | Edmonton | Alberta | Canada | T6G 2B7 |
| 246 | Providence Health Care | Vancouver | British Columbia | Canada | BC V6Z 2K5 |
| 247 | Georges L. Dumont Hospital | Moncton | New Brunswick | Canada | E1C 2Z3 |
| 248 | Dr. Saul Vizel Cardiac Research Office | Cambridge | Ontario | Canada | N1R 7R1 |
| 249 | Hamilton Health Sciences Corporation | Hamilton | Ontario | Canada | L8L 2X2 |
| 250 | London Health Sciences Centre | London | Ontario | Canada | N6A 5A5 |
| 251 | Southlake Regional Health Centre | Newmarket | Ontario | Canada | L3Y 2P4 |
| 252 | Halton Healthcare Services Corporation | Oakville | Ontario | Canada | L6M 0L8 |
| 253 | Kawartha Cardiology Clinical Trials | Peterborough | Ontario | Canada | K9J 0B2 |
| 254 | Toronto Sunnybrook Hospital | Toronto | Ontario | Canada | M4N 3M5 |
| 255 | Office of Dr. Anthony Glanz | Windsor | Ontario | Canada | N8X 5A6 |
| 256 | Clinique de Cardiologie de Levis | Levis | Quebec | Canada | G6V 4Z5 |
| 257 | Centre de Recherche du CHUM | Montreal | Quebec | Canada | H2L 4M1 |
| 258 | Montreal General Hospital | Montreal | Quebec | Canada | H3G 1A4 |
| 259 | CardioVasc HR | St Jean sur Richelieu | Quebec | Canada | J3A1C3 |
| 260 | CSSS du Sud de Lanaudiere - Hopital Pierre-Le Gardeur d/b/a CISSS de Lanaudiere | Terrebonne | Quebec | Canada | J6V 2H2 |
| 261 | CIUSSS de la Mauricie-et-du-Centre-du-Quebec | Trois-Rivières | Quebec | Canada | G8Z 3R9 |
| 262 | Royal University Hospital | Saskatoon | Saskatchewan | Canada | S7N 0W8 |
| 263 | Montreal Heart Institute | Quebec | Canada | 00 | |
| 264 | Centre de Recherche Clinique de Quebec | Quebec | Canada | G1J 1Z6 | |
| 265 | Institut Universitaire De Cardiologie Et De Pneumologie De Québec | Quebec | Canada | G1V 4G5 | |
| 266 | Hospital Clinico Regional Dr. Guillermo Grant Benavente | Concepcion | Chile | 4030000 | |
| 267 | Quantum Research | Puerto Varas | Chile | 5551070 | |
| 268 | Centro de Investigacion Clinica Universidad Catolica de Chile - CICUC | Santiago | Chile | 8330024 | |
| 269 | Hospital Las Higueras | Talcahuano | Chile | 4270918 | |
| 270 | Centro de Estudios Cardiologicos y de Medicina Interna | Temuco | Chile | 4780000 | |
| 271 | Centro de Investigacion Clinica del Sur | Temuco | Chile | 4781156 | |
| 272 | Centro de Estudios Clínicos V Región Ltda | Viña del Mar | Chile | 2520997 | |
| 273 | Baotou Central Hospital | Baotou | China | 014040 | |
| 274 | Beijing Anzhen Hospital, Capital Medical University | Beijing | China | 100029 | |
| 275 | Peking University First Hospital | Beijing | China | 100034 | |
| 276 | Beijing Shijitan Hospital | Beijing | China | 100038 | |
| 277 | Aerospace center hospital | Beijing | China | 100049 | |
| 278 | Beijing Friendship Hospital, Capital Medical University | Beijing | China | 100050 | |
| 279 | Chinese PLA General Hospital | Beijing | China | 100853 | |
| 280 | The First Hospital of Jilin University | Changchun | China | 130021 | |
| 281 | The Third Xiangya Hospital of Central South University | Changsha | China | 410013 | |
| 282 | Changzhou No.2 People's Hospital | Changzhou | China | 213000 | |
| 283 | West China Hospital, Sichuan University | Chengdu | China | 610041 | |
| 284 | Sichuan Provincial People's Hospital | Chengdu | China | 610072 | |
| 285 | The First Affiliated Hospital of Chongqing Medical University | Chongqing | China | 400016 | |
| 286 | Dongguan People's Hospital | Dongguan | China | 523059 | |
| 287 | The First Affiliated Hospital of Fujian Medical University | Fuzhou | China | 350005 | |
| 288 | Guangdong Provincial People's Hospital | Guangzhou | China | 510080 | |
| 289 | The First Affiliated Hospital of Sun Yat-Sen University | Guangzhou | China | 510080 | |
| 290 | GuiZhou Privicial People's Hospital | Guiyang | China | 550002 | |
| 291 | Zhejiang Provincial People's Hospital | Hangzhou | China | 310000 | |
| 292 | Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine | Hangzhou | China | 310006 | |
| 293 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Hangzhou | China | 310009 | |
| 294 | Sir Run Run Shaw Hospital, Zhejiang University School of Medicine | Hangzhou | China | 310016 | |
| 295 | Anhui Province Hospital | Hefei | China | 230001 | |
| 296 | Qilu Hospital of Shandong University | Jinan | China | 250012 | |
| 297 | The Second Affiliated Hospital, Shandong University | Jinan | China | 250033 | |
| 298 | Shandong Jining No.1 People's Hospital | Jining | China | 272011 | |
| 299 | Lanzhou University Second Hospital | Lanzhou | China | 730030 | |
| 300 | The Second Affiliatde Hospital To Nanchang University | Nanchang | China | 330006 | |
| 301 | Nanjing Drum Tower Hospital | Nanjing | China | 210000 | |
| 302 | Zhongda Hospital,Southeast University | Nanjing | China | 210009 | |
| 303 | Ningbo First Hospital | Ningbo | China | 315010 | |
| 304 | Shanghai Chest Hospital | Shanghai | China | 200030 | |
| 305 | Zhongshan Hospital,Fudan University | Shanghai | China | 200032 | |
| 306 | Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen | Shenzhen | China | 518052 | |
| 307 | The Second Affiliatted Hospital of Soochow University | Su Zhou | China | 210009 | |
| 308 | The First Affiliated Hospital of Soochow University | Suzhou | China | 215006 | |
| 309 | Shanxi Cardiovascular Hospital | Taiyuan | China | 030013 | |
| 310 | Tianjin Medical University General Hospital | Tianjin | China | 300052 | |
| 311 | Tianjin People's Hospital | Tianjin | China | 300121 | |
| 312 | Tianjin Chest Hospital | Tianjin | China | 300222 | |
| 313 | The First Affiliated Hospital of Wenzhou Medical University | Wenzhou | China | 325000 | |
| 314 | Wenzhou People's Hospital | Wenzhou | China | 325000 | |
| 315 | The Central Hospital of Wuhan | Wuhan | China | 430014 | |
| 316 | Hubei Zhongshan Hospital The Third People's Hospital of Hubei Province | Wuhan | China | 430033 | |
| 317 | Xinjiang Uygur Autonomous Region People's Hospital | Wulumuqi | China | 83004 | |
| 318 | The First Affiliated Hospital of Xi'an Jiaotong University | Xi'an | China | 710061 | |
| 319 | The Affiliated Hospital of Xuzhou Medical College | Xuzhou | China | ||
| 320 | Yanbian University Hospital | Yanji | China | 133000 | |
| 321 | Yichang Central Pepole's Hospital | Yichang | China | 443003 | |
| 322 | General Hospital of Ningxia Medical Hospital | Yinchuan | China | 750004 | |
| 323 | The First Affiliated Hospital of Zhengzhou University | Zhengzhou | China | 450052 | |
| 324 | Affiliated Hospital of Zunyi Medical University | Zunyi | China | 563000 | |
| 325 | Zupanijska bolnica Cakovec | Cakovec | Croatia | 40000 | |
| 326 | General Hospital Dubrovnik | Dubrovnik | Croatia | 20000 | |
| 327 | Special Hospital for medical rehabilitation | Krapinske Toplice | Croatia | 49217 | |
| 328 | Clinical Hospital Centre Rijeka | Rijeka | Croatia | 51000 | |
| 329 | General Hospital Slavonski Brod | Slavonski Brod | Croatia | 35000 | |
| 330 | OB Zabok | Zabok | Croatia | 49210 | |
| 331 | University Hospital Dubrava | Zagreb | Croatia | 10000 | |
| 332 | Fakultni nemocnice Brno | Brno | Czechia | 625 00 | |
| 333 | Vojenska nemocnice Brno | Brno | Czechia | 636 00 | |
| 334 | Fakultni nemocnice u sv. Anny v Brne | Brno | Czechia | 65691 | |
| 335 | Nemocnice Ceske Budejovice, a.s. | Ceske Budejovice | Czechia | 370 87 | |
| 336 | Fakultni nemocnice Hradec Kralove | Hradec Kralove | Czechia | 500 05 | |
| 337 | Kardiocentrum Vysocina CZ a.s. | Jihlava | Czechia | 586 01 | |
| 338 | Oblastní nemocnice Kolín | Kolin | Czechia | 280 02 | |
| 339 | Krajská nemocnice Liberec a.s. | Liberec | Czechia | 46001 | |
| 340 | Fakultni nemocnice Ostrava | Ostrava-Poruba | Czechia | 708 52 | |
| 341 | Mestska nemocnice Ostrava, p.o. | Ostrava | Czechia | 728 80 | |
| 342 | Pardubicka krajska nemocnice a.s. | Pardubice | Czechia | 530 03 | |
| 343 | Fakultni nemocnice Plzen | Plzen | Czechia | 304 60 | |
| 344 | MUDr. Eva Zídkova | Prague | Czechia | 158 00 | |
| 345 | Ústrední vojenské nemocnice Praha | Prague | Czechia | 169 02 | |
| 346 | Fakultni nemocnice Kralovske Vinohrady | Praha 10 | Czechia | 100 34 | |
| 347 | Kardiologie Vinohrady s r o | Praha 2 | Czechia | 120 00 | |
| 348 | Institut klinicke a experimentalni mediciny | Praha 4 | Czechia | 14000 | |
| 349 | Nemocnice Slany | Slany | Czechia | 274 01 | |
| 350 | Nemocnice AGEL - Podlesi a.s. | Trinec | Czechia | 73961 | |
| 351 | Aarhus University Hospital | Aahus N | Denmark | 8200 | |
| 352 | Amager Hospital | Copenhagen S | Denmark | 2300 | |
| 353 | Bispebjerg Og Frederiksberg Hospital | Frederiksberg | Denmark | 2000 | |
| 354 | Gentofte Hospital | Herlev | Denmark | 2730 | |
| 355 | Herning Regional Hospital | Herning | Denmark | 7400 | |
| 356 | Holbæk Sygehus | Holbæk | Denmark | 4300 | |
| 357 | Hvidovre Hospital | Hvidovre | Denmark | 2650 | |
| 358 | Sjællands University hospital | Koge | Denmark | 4600 | |
| 359 | Slagelse Sygehus | Slagelse | Denmark | 4200 | |
| 360 | Odense University Hospital | Svendborg | Denmark | 5700 | |
| 361 | Viborg Hospital | Viborg | Denmark | 8800 | |
| 362 | Ålborg Universitetshospital | Ålborg | Denmark | 9100 | |
| 363 | North Estonia Medical Centre Foundation | Tallinn | Estonia | 13419 | |
| 364 | Tartu University Hospital | Tartu | Estonia | 50406 | |
| 365 | CHU Angers - Hôpital Hôtel Dieu | Angers | France | 49100 | |
| 366 | CHRU de Tours - Hopital Trousseau | Chambray Les Tours | France | 37170 | |
| 367 | Centre Hospitalier Sud Francilien | Corbeil Essonnes cedex | France | 91106 | |
| 368 | Hopital Henri Mondor | Creteil | France | 94000 | |
| 369 | CHU Dijon | Dijon cedex | France | 21033 | |
| 370 | CHU de Grenoble - Hopital Albert Michallon | La Tronche | France | 38700 | |
| 371 | CH de Chartres - Hôpital Louis Pasteur | Le Coudray | France | 28630 | |
| 372 | CHRU de Lille - Hopital Claude Huriez | Lille Cedex | France | 59037 | |
| 373 | CHU de Limoges, Hopital Dupuytren | Limoges | France | 87000 | |
| 374 | Centre Hospitalier Saint Joseph Et Saint Luc | Lyon | France | 69007 | |
| 375 | Clinique Du Pont De Chaume | Montauban | France | 82017 | |
| 376 | CHU de Montpellier, Hopital Saint-Eloi | Montpellier | France | 34295 | |
| 377 | Centre Hospitalier Universitaire - de Nice - Hopital Pasteur | Nice Cedex 1 | France | 06002 | |
| 378 | Hôpital Caremeau | Nîmes Cedex 9 | France | 30029 | |
| 379 | Hopital Lariboisiere | Paris | France | 75010 | |
| 380 | Hopital Saint-Antoine | Paris | France | 75012 | |
| 381 | Hôpital Bichat - Claude Bernard | Paris | France | 75018 | |
| 382 | Hôpital du Haut Lévêque | Pessac | France | 33604 | |
| 383 | CHU Poitiers - Hôpital la Milétrie | Poitiers | France | 86000 | |
| 384 | CHU Rouen - Hopital Charles Nicolle | Rouen cedex | France | 76031 | |
| 385 | Clinique Saint-Hilaire - Centre Frédéric Joliot | Rouen | France | 78000 | |
| 386 | Hopital Rangueil | Toulouse Cedex 9 | France | 31059 | |
| 387 | CHU de Nancy - Hôpital de Brabois | Vandoeuvre les Nancy Cedex | France | 54500 | |
| 388 | Hopital Andre Mignot | Versailles Cedex | France | 78157 | |
| 389 | Klinikum am Plattenwald | Bad Friedrichshall | Germany | 74177 | |
| 390 | Universitaetsklinikum Freiburg | Bad Krozingen | Germany | 79189 | |
| 391 | Vivantes Klinikum Im Friedrichshain | Berlin | Germany | 10249 | |
| 392 | Charite Campus Benjamin Franklin | Berlin | Germany | 12200 | |
| 393 | Charité Campus Virchow | Berlin | Germany | 13353 | |
| 394 | Vivantes Humboldt Klinikum | Berlin | Germany | 13509 | |
| 395 | Klinikum Bielefeld | Bielefeld | Germany | 33604 | |
| 396 | Marienhausklinikum Eifel Bitburg | Bitburg | Germany | 54634 | |
| 397 | GFO Kliniken Bonn, Betriebsstaette St. Marien | Bonn-Beuel | Germany | 53225 | |
| 398 | Universitatsklinikum Bonn | Bonn | Germany | 53127 | |
| 399 | Hospital Bremen Mitte | Bremen | Germany | 28277 | |
| 400 | Regiomed Klinikum Coburg | Coburg | Germany | 96450 | |
| 401 | St. Johannes-Hospital | Dortmund | Germany | 44137 | |
| 402 | Krankenhaus Dresden-Friedrichstadt - Städtisches Klinikum | Dresden | Germany | 01067 | |
| 403 | Universitaetsklinikum Duesseldorf | Duesseldorf | Germany | 40225 | |
| 404 | Katholisches Krankenhaus St. Josef gGmbH - Abtlg. für Gynäkologie | Erfurt | Germany | 99097 | |
| 405 | Klinikum der Johann Wolfgang Goethe -Universitaet | Frankfurt | Germany | 60590 | |
| 406 | Klinikum Frankfurt Hoechst GmbH | Frankfurt | Germany | 65929 | |
| 407 | Universitaetsmedizin Greifswald | Greifswald | Germany | 17475 | |
| 408 | Universitaetsklinikum Hamburg Eppendorf | Hamburg | Germany | 20246 | |
| 409 | Asklepios Klinik St. Georg | Hamburg | Germany | 22587 | |
| 410 | Klinikum Leverkusen gGmbH | Leverkusen | Germany | 51375 | |
| 411 | Herzzentrum Ludwigshafen | Ludwigshafen | Germany | 67063 | |
| 412 | Klinikum Luedenscheid | Luedenscheid | Germany | 58515 | |
| 413 | Universitätsklinikum Magdeburg | Magdeburg | Germany | 39120 | |
| 414 | Katholisches Klinikum Mainz; Innere Medizin I- Kardiologie | Mainz | Germany | 55131 | |
| 415 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Mainz | Germany | 55131 | |
| 416 | Kliniken Maria Hilf GmbH | Moenchengladbach | Germany | 41063 | |
| 417 | Marienhaus Klinikum | Neuwied | Germany | 56564 | |
| 418 | Sana-Klinikum Remscheid GmbH | Remscheid | Germany | 42859 | |
| 419 | Universitaetsmedizin Rostock | Rostock | Germany | 18057 | |
| 420 | Universitaetsklinikum Tuebingen | Tübingen | Germany | 72076 | |
| 421 | Stadtkrankenhaus Worms | Worms | Germany | 67550 | |
| 422 | Uni General Hospital of Alexandroupolis | Alexandroupolis | Greece | 68100 | |
| 423 | Alexandra General Hospital of Athens | Athens Attica | Greece | 115 28 | |
| 424 | Hippokration Hospital | Athens | Greece | 11527 | |
| 425 | General Hospital of Athens Attikon | Athens | Greece | 12462 | |
| 426 | Athens Medical Center | Athens | Greece | 15125 | |
| 427 | General Hospital of Athens 'G. Gennimatas' | Athens | Greece | 15669 | |
| 428 | General Per Hospital of Athens Asklipiio Voulas | Athens | Greece | 16673 | |
| 429 | University Hospital of Heraklion | Heraklion | Greece | 71110 | |
| 430 | University General Hospital of Ioannina | Ioannina | Greece | 45500 | |
| 431 | University Hospital Of Larissa | Larissa | Greece | 41110 | |
| 432 | General University Hospital of Patras | Patra | Greece | 26500 | |
| 433 | Ahepa University General Hospital of Thessaloniki | Thessaloniki | Greece | 54636 | |
| 434 | Hippokration Hospital | Thessaloniki | Greece | 54642 | |
| 435 | Papageorgiou General Hospital | Thessaloniki | Greece | 56429 | |
| 436 | Papanikolaou General Hospital of Thessaloniki | Thessaloniki | Greece | 57010 | |
| 437 | Budai Irgalmasrendi Korhaz | Budapest | Hungary | 1023 | |
| 438 | Semmelweis Egyetem | Budapest | Hungary | 1085 | |
| 439 | Gottsegen György Országos Kardiológiai Intézet | Budapest | Hungary | 1096 | |
| 440 | Bajcsy-Zsilinszky Kórház és Rendelőintézet | Budapest | Hungary | 1106 | |
| 441 | Semmelweis Egyetem Városmajor Szív- és Érgyógyászati Klinika | Budapest | Hungary | 1122 | |
| 442 | Magyar Honvedseg Egeszsegugyi Kozpont | Budapest | Hungary | 1134 | |
| 443 | Debreceni Egyetem | Debrecen | Hungary | 4032 | |
| 444 | Petz Aladar Megyei Oktato Korhaz | Gyor | Hungary | 9023 | |
| 445 | Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz | Gyula | Hungary | 5700 | |
| 446 | Somogy Megyei Kaposi Mor Oktato Korhaz | Kaposvar | Hungary | 7400 | |
| 447 | Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz | Miskolc | Hungary | 3526 | |
| 448 | Pecsi Tudomanyegyetem | Pecs | Hungary | 7624 | |
| 449 | Szegedi Tudományegyetem Áok Szent-Györgyi Albert Klinikai Központ | Szeged | Hungary | 6725 | |
| 450 | Tolna Megyei Balassa János Kórház | Szekszárd | Hungary | 7100 | |
| 451 | Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz-Rendelointez | Szolnok | Hungary | 5000 | |
| 452 | Markusovszky Egyetemi Oktatokorhaz | Szombathely | Hungary | 9700 | |
| 453 | Zala Megyei Szent Rafael Korhaz | Zalaegerszeg | Hungary | 8900 | |
| 454 | Jawaharlal Nehru Medical College and Hospital | Aligarh | India | 202001 | |
| 455 | Fortis Escorts Heart Institute and Research Centre | Amritsar | India | 143004 | |
| 456 | St. John's National Academy of Health Sciences - St. John's Medical College Hospital | Bangalore | India | 560034 | |
| 457 | Sri Jayadeva Institute | Bangalore | India | 560069 | |
| 458 | KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre (MRC) | Belgaum | India | 590010 | |
| 459 | Apollo Hospitals | Chennai | India | 600006 | |
| 460 | Lisie Hospital | Cochin | India | 682018 | |
| 461 | Batra Hospital And Medical Research Centre | Delhi | India | 110062 | |
| 462 | Fortis Escorts Heart Institute and Research Centre | Faridabad | India | 121001 | |
| 463 | Osmania General Hospital | Hyderabad | India | 500012 | |
| 464 | Care Hospitals | Hyderbad | India | 500034 | |
| 465 | IPGMER and SSKM Hospital | Kolkata | India | 700020 | |
| 466 | B. M. Birla Heart Research Centre | Kolkata | India | 700027 | |
| 467 | Rabindranath Tagore International Institute of Cardiac Sciences | Kolkata | India | 700099 | |
| 468 | Dayanand Medical College & Hospital, Tagore Nagar, Civil Lines | Ludhiana | India | 141001 | |
| 469 | Kasturba Medical College Hospital | Mangalore | India | 575001 | |
| 470 | Seth G. S. Medical College and KEM Hospital | Mumbai | India | 400012 | |
| 471 | Manipal Hospital | Mysore | India | 570015 | |
| 472 | Arneja Heart Institute | Nagpur | India | 440010 | |
| 473 | Crescent Hospital & Heart Center | Nagpur | India | 440012 | |
| 474 | Central India Cardiology Hospital and Research Institute | Nagpur | India | 440015 | |
| 475 | Sir Ganga Ram Hospital | New Delhi | India | 110060 | |
| 476 | Ruby Hall Clinic | Pune | India | 411001 | |
| 477 | KEM Hospital & Research Centre | Pune | India | 411011 | |
| 478 | Nanjappa Hospital | Shimoga | India | 577205 | |
| 479 | Unique Hospital | Surat | India | 395002 | |
| 480 | Aashirwad Hospital | Ulhasnagar | India | 421001 | |
| 481 | Haemek Medical Center | Afula | Israel | 18101 | |
| 482 | Samson Assuta Ashdod University Hospital | Ashdod | Israel | 7747629 | |
| 483 | Barzilai Medical Center | Ashkelon | Israel | 78278 | |
| 484 | Soroka University Medical Center | Beersheba | Israel | 84101 | |
| 485 | Bnai Zion Medical Center | Haifa | Israel | 31048 | |
| 486 | Rambam Health Care Campus | Haifa | Israel | 31096 | |
| 487 | Carmel Medical Center | Haifa | Israel | 3436212 | |
| 488 | Wolfson Medical Center | Holon | Israel | 58100 | |
| 489 | Shaare Zedek Medical Center | Jerusalem | Israel | 9103102 | |
| 490 | Hadassah University Hospita - Ein Kerem | Jerusalem | Israel | 9112001 | |
| 491 | Hadassah Medical Center | Jerusalem | Israel | 9124001 | |
| 492 | Meir Medical Center | Kfar-Sava | Israel | 4428164 | |
| 493 | Health Corporation of Galilee Medical Center | Naharya | Israel | 2633737 | |
| 494 | Rabin Medical Center | Petah Tikva | Israel | 49100 | |
| 495 | Chaim Sheba Medical Center | Ramat Gan | Israel | 5262001 | |
| 496 | Kaplan Medical Center | Rechovot | Israel | 7610001 | |
| 497 | Assaf Harofeh Medical Center | Rishon Lezion | Israel | 70300 | |
| 498 | Ziv Medical Center | Safed | Israel | 13100 | |
| 499 | Baruch Padeh Medical Center | Tiberias | Israel | 15208 | |
| 500 | Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo Alessandria | Alessandria | Italy | 15121 | |
| 501 | Cliniche Humanitas Gavazzeni | Bergamo | Italy | 24125 | |
| 502 | Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII) | Bergamo | Italy | 24127 | |
| 503 | Azienda USL di Bologna - Ospedale Maggiore | Bologna | Italy | 40100 | |
| 504 | Università D'Annunzio | Chieti | Italy | 66013 | |
| 505 | Ospedale Sant'Andrea | La Spezia | Italy | 19021 | |
| 506 | Azienda Ulss 3 Serenissima distretto di Mirano | Mestre | Italy | 30035 | |
| 507 | Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico | Milano | Italy | 20122 | |
| 508 | Ospedale San Raffaele | Milano | Italy | 20132 | |
| 509 | Centro Cardiologico Monzino | Milano | Italy | 20138 | |
| 510 | Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda) | Milano | Italy | 20162 | |
| 511 | Azienda Ospedaliera Universitaria Federico II | Napoli | Italy | 80131 | |
| 512 | Fondazione IRCCS Policlinico San Matteo | Pavia | Italy | 27100 | |
| 513 | A. O.U. Pisana Ospedale di Cisanello | Pisa | Italy | 56124 | |
| 514 | Fondazione Policlinico Universitario A. Gemelli IRCCS | Roma | Italy | 00168 | |
| 515 | Azienda ospedaliera Sant'Andrea di Roma- Università di Roma La Sapienza | Roma | Italy | 00189 | |
| 516 | Istituto Clinico Humanitas | Rozzano | Italy | 20089 | |
| 517 | Ospedale San Francesco | Sassari | Italy | 07100 | |
| 518 | Ospedale Bolognini | Seriate | Italy | 24068 | |
| 519 | Azienda Ospedaliero Universitaria Ospedali Riuniti | Torrette Di Ancona | Italy | 60126 | |
| 520 | IRCCS Fondazione Salvatore Maugeri-Istituto Scientifico di Riabilitazione di Tradate | Tradate | Italy | 21049 | |
| 521 | Azienda Ospedaliera Ospedale Treviglio-Caravaggio di Treviglio | Treviglio | Italy | 24047 | |
| 522 | Regione Del Veneto ULSS 2 Marca Trevigiana | Treviso | Italy | 31100 | |
| 523 | Kasugai Municipal Hospital | Aichi | Japan | 486-8510 | |
| 524 | Funabashi Munitiple Medical Center | Chiba | Japan | 273-8588 | |
| 525 | Fukui Prefectural Hospital | Fukui-shi | Japan | 910-0846 | |
| 526 | Fukuoka Wajiro Hospital | Fukuoka-shi | Japan | 811-0213 | |
| 527 | Gifu Prefectural General Medical Center | Gifu | Japan | 500-8717 | |
| 528 | National Hospital Organization Takasaki General Medical Center | Gunma | Japan | 370-0829 | |
| 529 | Hyogo Prefectural Harima-Himeji General Medical Center | Himeji-shi | Japan | 670-8560 | |
| 530 | Hirosaki University Hospital | Hirosaki | Japan | 036-8203 | |
| 531 | Hiroshima City Hiroshima Citizens Hospital | Hiroshima | Japan | 730-8518 | |
| 532 | Tokai University Hospital | Isehara | Japan | 259-1193 | |
| 533 | Public Central Hospital of Matto Ishikawa | Ishikawa | Japan | 924-0865 | |
| 534 | Showa University Fujigaoka Hospital | Kanagawa | Japan | 227-8501 | |
| 535 | Fukuoka Tokushukai Hospital | Kasuga-shi | Japan | 816-0864 | |
| 536 | Kimitsu Chuo Hospital | Kisarazu-shi | Japan | 292-8535 | |
| 537 | Kokura Memorial Hospital | Kitakyushu-shi | Japan | 802-8555 | |
| 538 | Chikamori Hospital | Kochi | Japan | 780-8522 | |
| 539 | National Hospital Organization Fukuoka Higashi Medical Center | Koga | Japan | 811-3195 | |
| 540 | Saiseikai Kumamoto Hospital | Kumamoto-shi | Japan | 861-4193 | |
| 541 | Kurashiki Central Hospital | Kurashiki | Japan | 710-8602 | |
| 542 | National Hospital Organization Kure Medical Center and Chugoku Cancer Center | Kure-shi | Japan | 736-0023 | |
| 543 | Kyoto University Hospital | Kyoto-shi | Japan | 606-8507 | |
| 544 | Chiba-Nishi General Hospital | Matsudo-shi | Japan | 270-2251 | |
| 545 | Jisenkai Aizawa Hospital | Matsumoto-shi | Japan | 390-8510 | |
| 546 | Toho University Medical Center, Ohashi Hospital | Meguro-ku | Japan | 153-8515 | |
| 547 | Tokyo Saiseikai Central Hospital | Minato-ku | Japan | 108-0073 | |
| 548 | Miyazaki Medical Association Hospital | Miyazaki-shi | Japan | 880-2102 | |
| 549 | Nagano Chuo Hospital | Nagano-shi | Japan | 380-0814 | |
| 550 | NHO Nagoya Medical Center | Nagoya-shi | Japan | 460-0001 | |
| 551 | Japanese Red Cross Nagoya Daiichi Hospital | Nagoya-shi | Japan | 466-8650 | |
| 552 | Okayama Rosai Hospital | Okayama-shi | Japan | 702-8055 | |
| 553 | National Hospital Organization Osaka National Hospital | Osaka-shi | Japan | 540-0006 | |
| 554 | Osaka City General Hospital | Osaka | Japan | 534-0021 | |
| 555 | National Hospital Organization Saitama National Hospital | Saitama | Japan | 351-0102 | |
| 556 | Tohoku University Hospital | Sendai | Japan | 980-8574 | |
| 557 | Tokyo Women's Medical University Hospital | Shinjuku-ku | Japan | 162-8666 | |
| 558 | Iwate Medical University Hospital | Shiwa-gun | Japan | 028-3695 | |
| 559 | National Cerebral and Cardiovascular Center | Suita-Shi | Japan | 564-8565 | |
| 560 | Kagawa Prefectural Central Hospital | Takamatsu | Japan | 760-8557 | |
| 561 | Tokushima University Hospital | Tokushima | Japan | 770-8503 | |
| 562 | Mitsui Memorial Hospital | Tokyo | Japan | 101-8643 | |
| 563 | Nippon Medical School Hospital | Tokyo | Japan | 113-8603 | |
| 564 | National Hospital Organization Tokyo Medical Center | Tokyo | Japan | 152-8902 | |
| 565 | Teikyo University Hospital | Tokyo | Japan | 173-8606 | |
| 566 | Nihon University Itabashi Hospital | Tokyo | Japan | 173-8610 | |
| 567 | Ome Municipal General Hospital | Tokyo | Japan | 198-0042 | |
| 568 | Tsukuba Medical Center Hospital | Tsukuba-City | Japan | 305-8558 | |
| 569 | Yamaguchi University Hospital | Ube | Japan | 755-8505 | |
| 570 | Tokyobay Urayasu Ichikawa Medical Center | Urayasu-shi | Japan | 279-0001 | |
| 571 | Wakayama Medical University Hospital | Wakayama | Japan | 641-8510 | |
| 572 | Yokohama City University Medical Center | Yokohama | Japan | 232-0024 | |
| 573 | Inje University Busan Paik Hospital | Busan | Korea, Republic of | 47392 | |
| 574 | Pusan National University Hospital | Busan | Korea, Republic of | 49241 | |
| 575 | Dong-A University Hospital | Busan | Korea, Republic of | 602-812 | |
| 576 | Chungbuk National University Hospital | Cheongju-si | Korea, Republic of | 28644 | |
| 577 | Kangwon National University Hospital | Chuncheon | Korea, Republic of | 24289 | |
| 578 | Keimyung University Dongsan Hospital | Daegu | Korea, Republic of | 42601 | |
| 579 | Konyang University Hospital | Daejeon | Korea, Republic of | 302-718 | |
| 580 | Chungnam National University Hospital | Daejeon | Korea, Republic of | 35015 | |
| 581 | Ewha Womans University Mokdong Hospital | Gangseo-gu | Korea, Republic of | 7804 | |
| 582 | Myongji Hospital | Goyang-si | Korea, Republic of | 10475 | |
| 583 | Chonnam National University Hospital | Gwangju | Korea, Republic of | 61469 | |
| 584 | Seoul National University Bundang Hospital | Gyeonggi-do | Korea, Republic of | 13620 | |
| 585 | Gachon University Gil Medical Center | Incheon | Korea, Republic of | 21565 | |
| 586 | The Catholic University of Korea, Incheon St. Mary's Hospital | Incheon | Korea, Republic of | 403-720 | |
| 587 | Chungnam National University Hospital | Sejong-si | Korea, Republic of | 30099 | |
| 588 | Korea University Anam Hospital | Seoul | Korea, Republic of | 02841 | |
| 589 | Seoul National University Hospital | Seoul | Korea, Republic of | 03080 | |
| 590 | VHS Medical Center | Seoul | Korea, Republic of | 05368 | |
| 591 | Asan Medical Center | Seoul | Korea, Republic of | 05505 | |
| 592 | Gangnam Severance Hospital, Yonsei University Health System | Seoul | Korea, Republic of | 06273 | |
| 593 | Seoul St.Mary's Hospital | Seoul | Korea, Republic of | 06591 | |
| 594 | Severance Hospital, Yonsei University Health System | Seoul | Korea, Republic of | 120-752 | |
| 595 | Kyung Hee University Hospital at Gangdong | Seoul | Korea, Republic of | 134-727 | |
| 596 | Kyung Hee University Hospital | Seoul | Korea, Republic of | 2447 | |
| 597 | Korea University Guro Hospital | Seoul | Korea, Republic of | 8308 | |
| 598 | WonJu Severance Christian Hospital | Wonju | Korea, Republic of | 220-701 | |
| 599 | Pusan National University Yangsan Hospital | Yangsan-si | Korea, Republic of | 50612 | |
| 600 | Daugavpils Regional Hospital | Daugavpils | Latvia | LV5417 | |
| 601 | Regional Hospital of Liepaja | Liepaja | Latvia | LV-3414 | |
| 602 | Riga East Clinical University Hospital | Riga | Latvia | LV-1038 | |
| 603 | Pauls Stradins Clinical University Hospital | Riga | Latvia | LV1002 | |
| 604 | Klinikiniai sprendimai JSC | Kaunas | Lithuania | 49387 | |
| 605 | Hospital of Lithuanian University of Health Sciences Kaunas Clinics | Kaunas | Lithuania | LT-50161 | |
| 606 | Klaipeda Seamen's Hospital, Public Institution | Klaipeda | Lithuania | LT-92288 | |
| 607 | Panevezys Republican Hospital, Public Institution | Panevezys | Lithuania | LT35144 | |
| 608 | Siauliai Republican Hospital, Public Institution | Siauliai | Lithuania | LT-76231 | |
| 609 | Vilnius University Hospital Santariskiu Clinic, Public Institution | Vilnius | Lithuania | LT-08661 | |
| 610 | Hospital University Sains Malaysia | Kota Bharu | Malaysia | 15200 | |
| 611 | Hospital Queen Elizabeth | Kota Kinabalu | Malaysia | 88500 | |
| 612 | Sarawak General Hospital | Kuching | Malaysia | 93200 | |
| 613 | Hospital Miri | Miri | Malaysia | 98000 | |
| 614 | Hospital Pulau Pinang | Pulau Pinang | Malaysia | 10990 | |
| 615 | Universiti Teknologi Mara | Selayang | Malaysia | 68000 | |
| 616 | Hospital Cardiologica Aguascalientes | Aguascalientes | Mexico | 20230 | |
| 617 | Centro para el Desarrollo de la Medicina y de Asistencia Médica Especializada S.C. | Culiacan | Mexico | 80230 | |
| 618 | Consultorio Privado del Dr. Gabriel Arturo Ramos Lopez | Guadalajara | Mexico | 44210 | |
| 619 | Medica del Este | Jalapa | Mexico | 91140 | |
| 620 | Centro de Estudios de de alta Especialidad de Sinaloa | Mazatlan | Mexico | 82126 | |
| 621 | Private Practice Dr Amaya | Monterrey | Mexico | 64718 | |
| 622 | Centro de Estudios Clinicos de Queretaro S.C | Queretaro | Mexico | 76000 | |
| 623 | Centro de Atencion e Investigacion Cardiovascular del Potosi, S.C. | San Luis Potosí | Mexico | 78200 | |
| 624 | Centro de Investigacion Cardiovascular y Metabolica | Tijuana | Mexico | 22500 | |
| 625 | Centro de Investigacion Dr. Alberto Esteban Bazzoni Ruiz | Torreon | Mexico | 27000 | |
| 626 | Centro de Alta Especialidad 'Dr. Rafael Lucio' | Xalapa | Mexico | 91020 | |
| 627 | Noordwest Ziekenhuisgroep | Alkmaar | Netherlands | 1815 JD | |
| 628 | Ziekenhuisgroep Twente | Almelo | Netherlands | 7609PP | |
| 629 | Onze Lieve Vrouwe Gasthuis | Amsterdam | Netherlands | 1091 AC | |
| 630 | MC Haaglanden Lok.Westeinde - Afd.Interne | Den Haag | Netherlands | 2512 VA | |
| 631 | Ziekenhuis Gelderse Vallei | Ede | Netherlands | 6716 RP | |
| 632 | Catharina Ziekenhuis | Eindhoven | Netherlands | 5623 EJ | |
| 633 | Medisch Spectrum Twente | Enschede | Netherlands | 7512 KZ | |
| 634 | Admiraal De Ruyter Ziekenhuis - Goes | Goes | Netherlands | 4462 RA | |
| 635 | Groene Hart Ziekenhuis | Gouda | Netherlands | 2803 HH | |
| 636 | Elkerliek Ziekenhuis | Helmond | Netherlands | 5707 HA | |
| 637 | St. Antonius Ziekenhuis Nieuwegein | Nieuwegein | Netherlands | 3435 CM | |
| 638 | Radboudumc | Nijmegen | Netherlands | 6525GA | |
| 639 | Canisius-Wilhelmina Ziekenhuis | Nijmegen | Netherlands | 6532SZ | |
| 640 | Laurentius Hospital | Roermond | Netherlands | 6043 CV | |
| 641 | Sint Franciscus Gasthuis | Rotterdam | Netherlands | 3045 PM | |
| 642 | Maxima Medisch Centrum | Veldhoven | Netherlands | 5504 DB | |
| 643 | VieCuri Medisch Centrum | Venlo | Netherlands | 5912 BL | |
| 644 | Gelre Ziekenhuizen Zutphen | Zutphen | Netherlands | 7207 AE | |
| 645 | North Shore Hospital | Auckland | New Zealand | 0740 | |
| 646 | Auckland City Hospital | Auckland | New Zealand | 1030 | |
| 647 | University of Otago | Christchurch | New Zealand | 4710 | |
| 648 | Dunedin Public Hospital | Dunedin | New Zealand | 9016 | |
| 649 | Hawkes Bay Hospital | Hastings | New Zealand | 4120 | |
| 650 | Taranaki Base Hospital | New Plymouth | New Zealand | 4342 | |
| 651 | Middlemore Hospital | Otahuhu | New Zealand | 2025 | |
| 652 | Rotorua Hospital | Rotorua | New Zealand | 3010 | |
| 653 | Tauranga Hospital | Tauranga | New Zealand | 3143 | |
| 654 | The Heart Specialists Clinic and Diagnostic Center | Angeles | Philippines | 2009 | |
| 655 | Baguio General Hospital and Medical Center | Baguio City | Philippines | 2600 | |
| 656 | De La Salle Health Sciences Institute- DLSUMC | Dasmarinas | Philippines | 4114 | |
| 657 | Central Lab Diabetes Wellness, Heart and Kidneys, Inc | Davao City, Davao Del Sur | Philippines | 8000 | |
| 658 | Davao Doctors Hospital | Davao | Philippines | 8000 | |
| 659 | Mariano Marcos Memorial Hospital and Medical Center | Ilocos Sur | Philippines | ||
| 660 | West Visayas State University Medical Center | Iloilo City | Philippines | 5000 | |
| 661 | St.Paul's Hospital-Iloilo | Iloilo | Philippines | 5000 | |
| 662 | Mary Mediatrix Medical Center | Lipa City | Philippines | 4217 | |
| 663 | Manila Doctors Hospital | Manila | Philippines | 1000 | |
| 664 | Medical Center Manila | Manila | Philippines | 1000 | |
| 665 | Chinese General Hospital & Medical Center | Manila | Philippines | 1003 | |
| 666 | Amang Rodriguez Memorial Medical Center | Marikina City | Philippines | 1800 | |
| 667 | Asian Hospital and Medical Center | Muntinlupa | Philippines | 1781 | |
| 668 | The Medical City | Pasig City | Philippines | 1605 | |
| 669 | Philippine Heart Center | Quezon City | Philippines | 1100 | |
| 670 | St. Luke's Medical Center | Quezon | Philippines | 1102 | |
| 671 | Cardinal Santos Medical Center | San Juan | Philippines | 1502 | |
| 672 | Uniwersytecki Szpital Kliniczny w Bialymstoku | Bialystok | Poland | 15-276 | |
| 673 | NZOZ Centrum Medyczne KERmed | Bydgoszcz | Poland | 85-231 | |
| 674 | Samodzielny Publiczny Zaklad Opieki Zdrowotnej | Bytom | Poland | 41-902 | |
| 675 | Wojewódzki Szpital Zespolony w Elblągu | Elbląg | Poland | 82-300 | |
| 676 | Clinical Medical Research Sp. z o.o. | Katowice | Poland | 40-156 | |
| 677 | Specjalistyczna Poradnia Kardiologiczna i Nadcisnienia Tetniczego | Kielce | Poland | 25-525 | |
| 678 | Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska | Krakow | Poland | 30-082 | |
| 679 | Krakowskie Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii | Krakow | Poland | 30-693 | |
| 680 | Krakowski Szpital Specjalistyczny im Jana Pawla II | Krakow | Poland | 31-202 | |
| 681 | SPZOZ Centralny Szpital Kliniczny UM w Lodzi | Lodz | Poland | 92-213 | |
| 682 | 1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ w Lublinie | Lublin | Poland | 20-049 | |
| 683 | Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie | Lublin | Poland | 20-954 | |
| 684 | NZOZ Osrodek Kardiologii Inwazyjnej -Ikardia | Naleczow | Poland | 24-140 | |
| 685 | FutureMeds Olsztyn | Olsztyn | Poland | 10-010 | |
| 686 | Wojewodzki Szpital Specjalistyczny w Olsztynie | Olsztyn | Poland | 10-561 | |
| 687 | Ostrowieckie Centrum Medyczne Spolka Cywilna Anna Olech-Cudzik, Krzysztof Cudzik | Ostrowiec Swietokrzyski | Poland | 27-400 | |
| 688 | Medicome Sp. Z O.O. | Oswiecim | Poland | 32-600 | |
| 689 | Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu | Poznan | Poland | 61-848 | |
| 690 | Wojewodzki Szpital im. Sw. Ojcia Pio w Przemyslu | Przemysl | Poland | 37-700 | |
| 691 | Samodzielny Publiczny Szpital Wojewodzki im. Papieza Jana Pawla II | Siedlce | Poland | 08-110 | |
| 692 | ETG Skierniewice | Skierniewice | Poland | 96-100 | |
| 693 | NZOZ PRO CORDIS Sopockie Centrum Badan Kardiologicznych | Sopot | Poland | 81-717 | |
| 694 | Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu | Torun | Poland | 87-100 | |
| 695 | Centrum Medyczne Warszawskiego Uniwersytetu Medycznego | Warszawa | Poland | 02-097 | |
| 696 | Instytut Kardiologii im Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego | Warszawa | Poland | 04-628 | |
| 697 | Specjalistyczny Szpital im. dra Alfreda Sokołowskiego w Wałbrzychu | Wałbrzych | Poland | 58-309 | |
| 698 | Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu | Wroclaw | Poland | 50-368 | |
| 699 | 4 Wojskowy Szpital Kliniczny z Poliklinika SP ZOZ | Wroclaw | Poland | 50-981 | |
| 700 | Wojewodzki Szpital Specjalistyczny we Wroclawiu | Wroclaw | Poland | 51-124 | |
| 701 | Slaskie Centrum Chorob Serca | Zabrze | Poland | 41-800 | |
| 702 | Hospital Garcia de Orta, EPE | Almada | Portugal | 2805-267 | |
| 703 | Centro Hospitalar do Baixo Vouga, E.P.E. - Unidade de Aveiro | Aveiro | Portugal | 3814-501 | |
| 704 | Hospital de Braga | Braga | Portugal | 4710-243 | |
| 705 | Chuc - Hosp. Da Univ. de Coimbra | Coimbra | Portugal | 3000-075 | |
| 706 | Centro Hospitalar Cova da Beira, EPE - Hospital Pêro da Covilhã | Covilha | Portugal | 6200-074 | |
| 707 | Hosp. Sra. Da Oliveira - Guimaraes | Guimarães | Portugal | 4835-044 | |
| 708 | Centro Hospitalar de Leiria | Leiria | Portugal | 2410-197 | |
| 709 | Centro Hospitalar de Lisboa Norte - Hospital Santa Maria | Lisboa | Portugal | 1649-035 | |
| 710 | Centro Hospitalar de Lisboa Central | Lisbon | Portugal | 1169-024 | |
| 711 | Centro Hospitalar de Entre o Douro e Vouga, E.P.E | Santa Maria da Feira | Portugal | 4520-211 | |
| 712 | Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E. | Vila Nova de Gaia | Portugal | 4434-502 | |
| 713 | Centro Hospitalar de Trás os Montes e Alto Douro- Vila Real | Vila Real | Portugal | 5000-508 | |
| 714 | Spitalul Judetean de Urgenta Dr. Constantin Opris | Baia-Mare | Romania | 430031 | |
| 715 | Spitalul Clinic Judetean de Urgenta Brasov | Brasov | Romania | 500365 | |
| 716 | Institutul de urgenta pentru Boli Cardiovasculare Prof. Dr. C.C. Iliescu Sectia cardiologie III | Bucharest | Romania | 022328 | |
| 717 | Spitalul Universitar de Urgenta Militar Central 'Dr. Carol Davila' | Bucuresti | Romania | 010825 | |
| 718 | Spitalul Universitar de Urgenta Elias, Clinica de Cardiologie | Bucuresti | Romania | 011461 | |
| 719 | Spitalul Clinic de Urgenta Bucuresti | Bucuresti | Romania | 014461 | |
| 720 | Spitalul Clinic Colentina | Bucuresti | Romania | 020125 | |
| 721 | Spitalul Universitar de Urgenta Bucuresti | Bucuresti | Romania | 050098 | |
| 722 | Spitalul Angiocare SRL | Cluj-Napoca | Romania | 400000 | |
| 723 | Institutul Inimiii Niculae Stancioiu Cluj Napoca | Cluj-Napoca | Romania | 400001 | |
| 724 | Spitalul Clinic Judetean de Urgenta Cluj Napoca | Cluj-Napoca | Romania | 400006 | |
| 725 | Spitalul Clinic Judetean de Urgenta Sf. Apostol Andrei | Constanta | Romania | 900591 | |
| 726 | Spitalul Clinic Judetean de Urgenta Craiova | Craiova | Romania | 200147 | |
| 727 | Institutul de Boli Cardiovasculare Iasi | Iasi | Romania | 700503 | |
| 728 | Spitalul Clinic Judetean de Urgenta Oradea | Oradea | Romania | 410167 | |
| 729 | SAL MED Pitesti | Pitesti | Romania | 110424 | |
| 730 | Spitalul Clinic Judetean de Urgenta Targu Mures | Targu-Mures | Romania | 540136 | |
| 731 | Spitalul Clinic Judetean de Urgenta Targu Mures | Tg. Mures | Romania | 540136 | |
| 732 | Clinica Medicaliss | Timisoara | Romania | 300043 | |
| 733 | Spitalul Clinic Municipal de Urgenta Timisoara | Timisoara | Romania | 300079 | |
| 734 | Institutul de Boli Cardiovasculare Timisoara | Timisoara | Romania | 300310 | |
| 735 | Institute for Cardiovascular diseases Dedinje | Belgrade | Serbia | 11000 | |
| 736 | University Clinical Center of Serbia | Belgrade | Serbia | 11000 | |
| 737 | University Clinical Hospital Center Dr Dragisa Misovic- Dedi | Belgrade | Serbia | 11000 | |
| 738 | University Clinical Hospital Center Dr Dragisa Misovic- Dedi | Belgrade | Serbia | 11080 | |
| 739 | University Clinical Center Kragujevac | Kragujevac | Serbia | 34000 | |
| 740 | Institute for Treatment and Rehabilitation Niska Banja | Niska Banja | Serbia | 18205 | |
| 741 | Clinical Center Nis | Nis | Serbia | 18000 | |
| 742 | General Hospital Pancevo | Pancevo | Serbia | 26000 | |
| 743 | General Hospital Smederevo | Smederevo | Serbia | 11300 | |
| 744 | Institute for Pulmonary Disease of Vojvodina | Sremska Kamenica | Serbia | 21204 | |
| 745 | Institute of Cardiovascular Diseases of Vojvodina | Sremska Kamenica | Serbia | 21204 | |
| 746 | General Hospital Sremska Mitrovica | Sremska Mitrovica | Serbia | 22000 | |
| 747 | General Hospital Uzice | Uzice | Serbia | 31000 | |
| 748 | Health Center Zajecar | Zajecar | Serbia | 19000 | |
| 749 | National University Hospital | Singapore | Singapore | 119074 | |
| 750 | Changi General Hospital | Singapore | Singapore | 529889 | |
| 751 | Stredoslovensky ustav srdcovych a cievnych chorob a.s | Banska Bystrica | Slovakia | 97401 | |
| 752 | Alian s.r.o. | Bardejov | Slovakia | 08501 | |
| 753 | Premedix Clinic | Bratislava | Slovakia | 811 02 | |
| 754 | Nemocnica s poliklinikou Brezno | Brezno | Slovakia | 977 01 | |
| 755 | Interno Kardio s r o | Kosice | Slovakia | 04001 | |
| 756 | Kardiologicka ambulancia CARDIO D&R s.r.o. | Kosice | Slovakia | 4022 | |
| 757 | Východoslovenský Ústav Srdcových A Cievnych Chorôb, A.S. | Košice | Slovakia | 040 11 | |
| 758 | Kardio 1 S.R.O. | Lucenec | Slovakia | 98439 | |
| 759 | Univerzitná nemocnica Martin | Martin | Slovakia | 036 59 | |
| 760 | Kardiologicka ambulancia MEDI M&M s.r.o. | Moldava nad Bodvou | Slovakia | 4501 | |
| 761 | Kardiocentrum Nitra s.r.o. | Nitra | Slovakia | 95001 | |
| 762 | Cardioinvest s.r.o. | Nove Zamky | Slovakia | 94052 | |
| 763 | Oddelenie dermatovenerológie FNsP J. A. Reimana Prešov | Presov | Slovakia | 08081 | |
| 764 | Interna SK s.r.o. | Svidnik | Slovakia | 08901 | |
| 765 | MEDIVASA s.r.o. | Zilina | Slovakia | 01001 | |
| 766 | Nemocnica AGEL Zvolen a s | Zvolen | Slovakia | 960 01 | |
| 767 | University of the Free State | Bloemfontein | South Africa | 9301 | |
| 768 | Panorama MediClinic | Cape Town | South Africa | 7500 | |
| 769 | Tread Research | Cape Town | South Africa | 7500 | |
| 770 | Tiervlei Trial Centre | Cape Town | South Africa | 7530 | |
| 771 | Groote Schur Hospital | Cape Town | South Africa | 7925 | |
| 772 | Johese Clinical Research | Centurion | South Africa | 0157 | |
| 773 | Durban Medical Centre | Durban | South Africa | 4001 | |
| 774 | Garda, RA | Johannesburg | South Africa | 2192 | |
| 775 | Dr J.M. Engelbrecht Trial Site | Somerset West | South Africa | 7130 | |
| 776 | Helderberg Research Institute | Somerset West | South Africa | 7130 | |
| 777 | Clinical Projects Research SA (PTY) LTD | Worcester | South Africa | 6850 | |
| 778 | Hosp. Gral. Univ. de Alicante | Alicante | Spain | 03010 | |
| 779 | Hosp. Del Mar | Barcelona | Spain | 08003 | |
| 780 | Hosp. de La Santa Creu I Sant Pau | Barcelona | Spain | 08025 | |
| 781 | Hosp. Univ. Vall D Hebron | Barcelona | Spain | 08035 | |
| 782 | Hosp. Clinic I Provincial de Barcelona | Barcelona | Spain | 08036 | |
| 783 | Hosp. Univ. Virgen de La Arrixaca | El Palmar | Spain | 30120 | |
| 784 | Hosp. de Cabuenes | Gijon | Spain | 33206 | |
| 785 | Hosp. Univ. Arnau de Vilanova de Lleida | Lleida | Spain | 25198 | |
| 786 | Hosp. Virgen de La Luz | Madrid | Spain | 28003 | |
| 787 | Hosp. Univ. de La Princesa | Madrid | Spain | 28006 | |
| 788 | Hosp. Univ. Ramon Y Cajal | Madrid | Spain | 28034 | |
| 789 | Hosp. Clinico San Carlos | Madrid | Spain | 28040 | |
| 790 | Hosp. Univ. 12 De Octubre | Madrid | Spain | 28041 | |
| 791 | Hosp. Univ. La Paz | Madrid | Spain | 28046 | |
| 792 | Hosp. Univ. Hm Monteprincipe | Madrid | Spain | 28660 | |
| 793 | Hosp. Virgen de La Victoria | Malaga | Spain | 29010 | |
| 794 | Hosp. de Manises | Manises | Spain | 46940 | |
| 795 | Complejo Hosp. de Navarra | Pamplona | Spain | 31008 | |
| 796 | Hosp. Clinico Univ. de Santiago | Santiago de Compostela | Spain | 15706 | |
| 797 | Hosp. Univ. Joan Xxiii | Tarragona | Spain | 43007 | |
| 798 | Hosp. Clinico Univ. De Valencia | Valencia | Spain | 46010 | |
| 799 | Hosp. Gral. Univ. Valencia | Valencia | Spain | 46014 | |
| 800 | Hosp. Alvaro Cunqueiro | Vigo | Spain | 36312 | |
| 801 | Hosp. Univ. Miguel Servet | Zaragoza | Spain | 50009 | |
| 802 | Changhua Christian Hospital | Changhua | Taiwan | 50006 | |
| 803 | Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung | Taiwan | 807 | |
| 804 | Far Eastern Memorial Hospital | New Taipei | Taiwan | 22060 | |
| 805 | National Taiwan University Hospital | Taipei | Taiwan | 10002 | |
| 806 | Taipei Veterans General Hospital | Taipei | Taiwan | 11217 | |
| 807 | Cheng Hsin General Hospital | Taipei | Taiwan | 112 | |
| 808 | Taipei Municipal Wanfang Hospital | Taipei | Taiwan | 116 | |
| 809 | Chang Gung Memorial Hospital- Linkou | Taoyuan County | Taiwan | 33305 | |
| 810 | Siriraj Hospital | Bangkoknoi | Thailand | 10700 | |
| 811 | Ramathibodi Hospital | Bangkok | Thailand | 10400 | |
| 812 | Maharaj Nakorn Chiang Mai Hospital | Chiangmai | Thailand | 50200 | |
| 813 | Srinagarind Hospital | Nai Mueang Subdistrict Mueang | Thailand | 40000 | |
| 814 | King Chulalongkorn Memorial Hospital | Pathum Wan | Thailand | 10330 | |
| 815 | Cukurova Universitesi Tip Fakultesi | Adana | Turkey | 01130 | |
| 816 | Afyon Kocatepe University Medical Faculty | Afyon | Turkey | 03200 | |
| 817 | Ankara Etlik Speciality Hospital | Ankara | Turkey | 06010 | |
| 818 | Ankara University Medical Faculty | Ankara | Turkey | 06100 | |
| 819 | Ankara Numune Research and Training Hospital | Ankara | Turkey | 06800 | |
| 820 | Medical Park Antalya Hospital Komplex | Antalya | Turkey | 07160 | |
| 821 | Bursa Yuksek Ihtisas Training and Research Hospital | Bursa | Turkey | 16330 | |
| 822 | Osmangazi University Medical Faculty | Eskisehir | Turkey | 26480 | |
| 823 | Bezmi Alem Vakif University Medical Faculty Hospital | Istanbul | Turkey | 34093 | |
| 824 | Marmara University Pendik Training Hospital | Istanbul | Turkey | 34899 | |
| 825 | Dokuz Eylul University Medical Faculty | Izmir | Turkey | 35340 | |
| 826 | Erciyes University Medical Faculty | Kayseri | Turkey | 38039 | |
| 827 | Kutahya Health Science University Evliya Celebi Research and Training Hospital | Kutahya | Turkey | 43040 | |
| 828 | Inonu University Medical Faculty | Malatya | Turkey | 44280 | |
| 829 | Ondokuz Mayis University | Samsun | Turkey | 55139 | |
| 830 | Basingstoke And North Hampshire Hospital | Basingstoke | United Kingdom | RG24 9NA | |
| 831 | Queen Elizabeth Hospital | Birmingham | United Kingdom | B15 2WB | |
| 832 | Birmingham Heartlands Hospital | Birmingham | United Kingdom | B9 5SS | |
| 833 | Blackpool Victoria Hospital | Blackpool | United Kingdom | FY3 8NR | |
| 834 | Royal Bournemouth Hospital | Bournemouth | United Kingdom | BH7 7DW | |
| 835 | University Hospital Bristol and Weston NHS trust | Bristol | United Kingdom | BS1 3NU | |
| 836 | Dorset County Hospital | Dorchester | United Kingdom | DT1 2JY | |
| 837 | Hairmyres Hospital | East Kilbride | United Kingdom | G75 8RG | |
| 838 | Royal Infirmary of Edinburgh | Edinburgh | United Kingdom | EH16 4SA | |
| 839 | Kingston Hospital | Kingston upon Thames | United Kingdom | KT2 7QB | |
| 840 | Leeds General Infirmary | Leeds | United Kingdom | LS1 3EX | |
| 841 | Glenfield Hospital | Leicester | United Kingdom | LE3 9QP | |
| 842 | Lincoln County Hospital | Lincoln | United Kingdom | LN2 5QY | |
| 843 | Altnagelvin Hospital | Londonderry | United Kingdom | BT47 6SB | |
| 844 | Barts Hospital | London | United Kingdom | EC1A 7BE | |
| 845 | Hammersmith Hospital | London | United Kingdom | W12 0HS | |
| 846 | James Cook University Hospital | Middlesbrough | United Kingdom | TS4 3BW | |
| 847 | Peterborough City Hospital | Peterborough | United Kingdom | PE3 9GZ | |
| 848 | Derriford Hospital | Plymouth | United Kingdom | PL6 8DH | |
| 849 | Lister Hospital | Stevenage | United Kingdom | SG1 4AB | |
| 850 | Morristown Hospital | Swansea | United Kingdom | SA6 6NL | |
| 851 | Musgrove Park Hospital | Taunton | United Kingdom | TA1 5DA | |
| 852 | Torbay Hospital-Devon | Torquay | United Kingdom | TQ2 7AA | |
| 853 | Royal Albert Edward Infirmary | Wigan | United Kingdom | WN1 2NN | |
| 854 | Yeovil District Hospital | Yeovil | United Kingdom | BA214AT | |
| 855 | Saint Paul General Hospital | Ha Noi | Vietnam | 100000 | |
| 856 | Bach Mai Hospital | Hanoi | Vietnam | 100000 | |
| 857 | 103 Military Hospital | Hanoi | Vietnam | ||
| 858 | Hanoi Heart Hospital | Hanoi | Vietnam | ||
| 859 | Hanoi Medical University Hospital | Hanoi | Vietnam | ||
| 860 | People's Hospital 115 | Ho Chi Minh | Vietnam | 700000 | |
| 861 | Tam Anh Hospital | Ho Chi Minh | Vietnam | 700000 | |
| 862 | Thong Nhat HOSPITAL | Ho Chi Minh | Vietnam | 700000 | |
| 863 | Tam Duc Heart Hospital | Ho Chi Minh | Vietnam |
Sponsors and Collaborators
- Janssen Research & Development, LLC
Investigators
- Study Director: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Janssen Research & Development, LLC
ClinicalTrials.gov Identifier:
NCT05754957
Other Study ID Numbers:
- CR109271
- 70033093ACS3003
First Posted:
Mar 6, 2023
Last Update Posted:
Mar 6, 2023
Last Verified:
Feb 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Studies a U.S. FDA-regulated Drug Product:
Yes
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: