EQUIP-ACS: European Quality Improvement Programme for Acute Coronary Syndromes
Sponsor
Royal Brompton & Harefield NHS Foundation Trust (Other)
Overall Status
Unknown status
CT.gov ID
NCT00716430
Collaborator
Uppsala University (Other), GlaxoSmithKline (Industry)
3,500
37
2
18.1
94.6
5.2
Study Details
Study Description
Brief Summary
The main hypothesis to be tested is that the use of a quality improvement programme will lead to measurable improvements in the management of care and use of evidence based treatments for patients presenting to hospital with non-ST elevation acute coronary syndromes.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
3500 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Health Services Research
Official Title:
Improving the Management of Non-ST Elevation Acute Coronary Syndrome: Systematic Evaluation of a Quality Improvement Programme
Study Start Date
:
Aug 1, 2007
Anticipated Primary Completion Date
:
Dec 1, 2008
Anticipated Study Completion Date
:
Feb 1, 2009
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: QI Quality Improvement Centres |
Behavioral: Quality Improvement Programme
Quality Improvement training programme
|
| No Intervention: Non-QI No Quality Improvement Programme |
Outcome Measures
Primary Outcome Measures
- Composite of 7 outcome measures to assess aggregate potential for improvement in care using the QI programme:1:risk stratification within 24 hrs, 2:early coronary angiography, 3:anticoagulation, 4:beta-blockers, 5:statins, 6:ACE-inhibitors, 7:Clopidogrel [10 months]
Secondary Outcome Measures
- Clinical outcomes at discharge including death and myocardial infarction [10 months]
- Estimated costs of care for patients [10 months]
- Estimated costs and economic evaluation of potential cost-effectiveness of QI programme [10 months]
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
to 80 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
Patients with a good clinical history of ACS and at least one of the following:
-
New or transient ST or T wave changes on the ECG consistent with acute myocardial ischaemia
-
Elevation of troponin or other cardiac markers to levels indicative of myocardial necrosis according to local laboratory values
Exclusion Criteria:
-
Evidence of persistent ST elevation on the ECG
-
Use of early reperfusion therapy
-
Patients >80 years
-
Patients transferred from another hospital
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Centre Hospitalier de la region d'Annecy | Annecy | France | ||
| 2 | Centre Hospitalier de Chambery | Chambery | France | ||
| 3 | Cardiology dept. B, CHU Hopital G. Montpied | Clermont Ferrand | France | ||
| 4 | CHU de Grenoble | Grenoble | France | ||
| 5 | Centre Hospitalier de Riom Guy Thomas | Riom | France | ||
| 6 | Hopitaux Drome Nord de Romans-sur-Isere | Romans-sur-Isere | France | ||
| 7 | Centre Hospitalier d'Ussel | Ussel | France | ||
| 8 | Centre Hospitalier Pierre Bazin | Voiron | France | ||
| 9 | Ospedale M. Bufalini | Cesena | Italy | ||
| 10 | Ospedale Morgagni-Pierantoni | Forli | Italy | ||
| 11 | Ospedale di Livorno | Livorno | Italy | ||
| 12 | Ospedale Generale Provinciale di Macerata | Macerata | Italy | ||
| 13 | Ospedale Civile di Mirano | Mirano | Italy | ||
| 14 | Szpital w Ciechanowie | Ciechanow | Poland | ||
| 15 | Szpital Zachodni | Grodzisk Mazowiecki | Poland | ||
| 16 | Szpital w Grojcu | Grojec | Poland | ||
| 17 | Swietofrzyskie Centrum Chorob Serca | Kielce | Poland | ||
| 18 | Szpital w Plocku | Plock | Poland | ||
| 19 | Radomski Szpital Specjalistyczny | Radom | Poland | ||
| 20 | Szpital Specjalistyczny SPZOZ w Radom | Radom | Poland | ||
| 21 | Szpital w Siedlcach | Siedlce | Poland | ||
| 22 | SP CSK- Medical University of Warsaw | Warsaw | Poland | ||
| 23 | Szpital we Wloclawku | Wloclawek | Poland | ||
| 24 | Hospital Universitario Germans Trias | Badalona | Spain | ||
| 25 | Hospital del Mar | Barcelona | Spain | ||
| 26 | Hospital Universitario Vall d'Hebron | Barcelona | Spain | ||
| 27 | Hospital Josep Trueta | Girona | Spain | ||
| 28 | Hospital Universitario Joan XXIII | Tarragona | Spain | ||
| 29 | Hospital de Terrassa | Terrassa-Barcelona | Spain | ||
| 30 | Hospital de Tortosa Virgen de la Cinta | Tortosa | Spain | ||
| 31 | Antrim Area Hospital | Antrim | United Kingdom | ||
| 32 | Barnet General Hospital | Barnet | United Kingdom | ||
| 33 | Basildon Hospital | Essex | United Kingdom | ||
| 34 | Warwick Hospital | Warwick | United Kingdom | ||
| 35 | Royal Albert Edward Infirmary | Wigan | United Kingdom | ||
| 36 | Yeovil District Hospital | Yeovil | United Kingdom | ||
| 37 | York District Hospital | York | United Kingdom |
Sponsors and Collaborators
- Royal Brompton & Harefield NHS Foundation Trust
- Uppsala University
- GlaxoSmithKline
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00716430
Other Study ID Numbers:
- EQUIP-ACS 1
First Posted:
Jul 16, 2008
Last Update Posted:
Jul 16, 2008
Last Verified:
Jul 1, 2008
Keywords provided by ,
,
Additional relevant MeSH terms: