Yogurt Probiotic Bacteria on Relieving Young Children Acute Gastroenteritis
Study Details
Study Description
Brief Summary
The goal of this clinical trial is to test the effect of mothers' application of yogurt probiotic bacteria on relieving their young children's acute gastroenteritis in children had two to five years old. The main hypothesis is children with acute gastroenteritis who receive yogurt probiotic bacteria exhibit less diarrhea, vomiting and dehydration than those who don't.The study subjects were divided into two equal groups (probiotic study group and control group).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| No Intervention: Control group Children with acute gastroenteritis received standard hospital care and the prescribed medication of control group for acute gastroenteritis. |
|
| Experimental: Probiotic Study Group Children with acute gastroenteritis received fresh probiotic yogurt (1st day of production) for three consecutive days in addition to standard hospital care and prescribed medication for acute gastroenteritis. |
Dietary Supplement: yogurt with probiotic bacteria
Children in probiotic study group were received 15 mg/kg of market available fresh probiotic yogurt after stopping vomiting every four to six hours for three consecutive days beside to the standard hospital care and the prescribed medication for acute gastroenteritis.
|
Outcome Measures
Primary Outcome Measures
- Experience of diarrhea [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
yes/no
- Consistency of diarrhea [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Soft/ watery/ abnormal constitute
- Amount of diarrhea [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Small / moderate/ large/ severe
- Frequency of diarrhea [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
times /day.
- Odor of diarrhea [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
No odor/ offensive odor
- Duration of diarrhea [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
/days.
- Experience of Vomiting [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Yes/ no
- Amount of Vomiting [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Small / moderate/ large/ severe
- Frequency of Vomiting [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
times /day.
- Consistency of Vomiting [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Soft/ watery/ abnormal constitute
- Duration of Vomiting [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
/days.
- General condition of child [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Normal/ Restless, irritable/ Lethargic or unconscious
- Eye [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Normal/ Sunken eyes/ Very Sunken eyes
- Thirsty [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Drink normally/ Drinks eagerly, thirsty/ Drinks poorly or unable to drink
- Skin pinch [before intervention, after 1st day of study, after 2nd day of study, and after 3rd day of study.]
Goes back quickly/ Goes back slowly/ Goes back very slowly
Other Outcome Measures
- children's age/ [before data collection]
year(s)
- gender/ [before data collection]
male, female
- residence/ [before data collection]
urban,rural
- type of feeding [before data collection]
breast feeding, bottle feeding, mixed type, ordinary
- diagnosis [before data collection]
gastroenteritis, bronchitis
- prescribed medication [before data collection]
antiemetics, fluids therapy, antibiotics
- children's weight [before data collection]
/kgs
Eligibility Criteria
Criteria
Inclusion Criteria:
- newly admitted children with no or some dehydration and with acute gastroenteritis.
Exclusion Criteria:
- bloody watery diarrhea
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | inpatient medical ward for gastroenteritis in El-Raml Children's Hospital (Wingat) at Alexandria. | Alexandria | Egypt |
Sponsors and Collaborators
- Alexandria University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Bertelsen RJ, Jensen ET, Ringel-Kulka T. Use of probiotics and prebiotics in infant feeding. Best Pract Res Clin Gastroenterol. 2016 Feb;30(1):39-48. doi: 10.1016/j.bpg.2016.01.001. Epub 2016 Jan 22.
- Cruchet S, Furnes R, Maruy A, Hebel E, Palacios J, Medina F, Ramirez N, Orsi M, Rondon L, Sdepanian V, Xochihua L, Ybarra M, Zablah RA. The use of probiotics in pediatric gastroenterology: a review of the literature and recommendations by Latin-American experts. Paediatr Drugs. 2015 Jun;17(3):199-216. doi: 10.1007/s40272-015-0124-6.
- Kluijfhout S, Trieu TV, Vandenplas Y. Efficacy of the Probiotic Probiotical Confirmed in Acute Gastroenteritis. Pediatr Gastroenterol Hepatol Nutr. 2020 Sep;23(5):464-471. doi: 10.5223/pghn.2020.23.5.464. Epub 2020 Aug 27.
- Sharif, A., Kheirkhah, D., Shamsesfandabadi, P., Masoudi, S., Ajorpaz, N., & Sharif, M. (2017, 01/01). Comparison of Regular and Probiotic Yogurts in Treatment of Acute Watery Diarrhea in Children. Journal of Probiotics & Health, 05. https://doi.org/10.4172/2329-8901.1000164
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