A Study of Acute Kidney Injury in Children at Sohag University Hospital

• Sponsor: Sohag University (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05297214
• Collaborator: (none)
• Enrollment: 50
• Location: 1
• Anticipated Duration (Months): 11.9
• Patients Per Site Per Month: 4.2

Study Details

Study Description

Brief Summary

Acute kidney injury (AKI) has been traditionally defined as an abrupt loss of kidney function leading to a rapid decline in the glomerular filtration rate (GFR), accumulation of waste products such as blood urea nitrogen (BUN) and creatinine, and dysregulation of extracellular volume and electrolyte homeostasis . Acute kidney injury (AKI) is a very common condition, especially among hospitalized patients.

this work aims to study the demographics, etiology, clinical characteristics, and outcome of acute kidney injury in children in Sohag University Hospital - Pediatrics Department.

Condition or Disease	Intervention/Treatment	Phase
Acute Kidney Injury	Diagnostic Test: serum creatinine and Other investigations will be done according to the case

Study Design

• Study Type: Observational
• Anticipated Enrollment: 50 participants
• Observational Model: Cohort
• Time Perspective: Cross-Sectional
• Official Title: A Study of Acute Kidney Injury in Children at Sohag University Hospital
• Actual Study Start Date: Jan 1, 2022
• Anticipated Primary Completion Date: Dec 30, 2022
• Anticipated Study Completion Date: Dec 30, 2022

Outcome Measures

Primary Outcome Measures

1. Serum creatinine level [one year]

   follow up AKI patients with serum creatinine level

Eligibility Criteria

Criteria

• Ages Eligible for Study: 1 Month to 16 Years
• Sexes Eligible for Study: All

Inclusion Criteria:

• All children with acute kidney injury with an age range from 1 month to 16 years old

Exclusion Criteria:

1. patients with chronic kidney disease (CKD)

2. Patients with irregular follow up

3. Patients with incomplete data

4. Patients whose medical guardians refuse participation in the study

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Sohag General Hospital	Sohag		Egypt

Sponsors and Collaborators

• Sohag University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

• Akcay A, Turkmen K, Lee D, Edelstein CL. Update on the diagnosis and management of acute kidney injury. Int J Nephrol Renovasc Dis. 2010;3:129-40. doi: 10.2147/IJNRD.S8641. Epub 2010 Sep 29.
• Kaddourah A, Basu RK, Bagshaw SM, Goldstein SL; AWARE Investigators. Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults. N Engl J Med. 2017 Jan 5;376(1):11-20. doi: 10.1056/NEJMoa1611391. Epub 2016 Nov 18.
• Lameire NH, De Vriese AS, Vanholder R. Prevention and nondialytic treatment of acute renal failure. Curr Opin Crit Care. 2003 Dec;9(6):481-90. Review.
• Tresa V, Yaseen A, Lanewala AA, Hashmi S, Khatri S, Ali I, Mubarak M. Etiology, clinical profile and short-term outcome of acute kidney injury in children at a tertiary care pediatric nephrology center in Pakistan. Ren Fail. 2017 Nov;39(1):26-31. doi: 10.1080/0886022X.2016.1244074. Epub 2016 Oct 21.

• Responsible Party: Omnia Abdelsabour Hassan, resident doctor at pediateric department sohag General hospital, Sohag University
• ClinicalTrials.gov Identifier: NCT05297214
• Other Study ID Numbers: soh-Med-22-03-11
• First Posted: Mar 28, 2022
• Last Update Posted: Mar 28, 2022
• Last Verified: Mar 1, 2022

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Acute Kidney Injury; Wounds and Injuries

Study Results

No Results Posted as of Mar 28, 2022