Investigating Temporal Improvements in Survival Following ST-elevation Myocardial Infarction.
Sponsor
University of Leeds (Other)
Overall Status
Completed
CT.gov ID
NCT03749694
Collaborator
(none)
232,353
113.9
Study Details
Study Description
Brief Summary
The aim of the study was to use data from the Myocardial Ischaemia National Audit Project (MINAP) to investigate whether temporal improvements in survival were associated with changes in patients' baseline clinical risk or use of guideline-indicated treatments for the management of STEMI, and to determine the extent to which associations explained the temporal improvements in survival.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
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Study Design
Study Type:
Observational [Patient Registry]
Actual Enrollment
:
232353 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Investigating Temporal Improvements in Survival Following ST-elevation Myocardial Infarction: A Causal Mediation Analysis Using the Myocardial Ischaemia National Audit Project, 2004-2013.
Actual Study Start Date
:
Jan 1, 2004
Actual Primary Completion Date
:
Jun 30, 2013
Actual Study Completion Date
:
Jun 30, 2013
Outcome Measures
Primary Outcome Measures
- All cause mortality [one year]
Secondary Outcome Measures
- All cause mortality [six months]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
aged 18 years or more
-
patients hospitalised with ST-elevation myocardial infarction
Exclusion Criteria:
- patients hospitalised with phenotypes other than ST-elevation myocardial infarction
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- University of Leeds
Investigators
- Principal Investigator: Chris P Gale, FRCP, University of Leeds
- Principal Investigator: Tatendashe B Dondo, PhD, University of Leeds
- Principal Investigator: Marlous Hall, PhD, University of Leeds
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Tatendashe Bernadette Dondo,
Postdoctoral medical statistician,
University of Leeds
ClinicalTrials.gov Identifier:
NCT03749694
Other Study ID Numbers:
- PG/13/81/30474_STEMI
First Posted:
Nov 21, 2018
Last Update Posted:
Nov 21, 2018
Last Verified:
Nov 1, 2018
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Tatendashe Bernadette Dondo,
Postdoctoral medical statistician,
University of Leeds
Additional relevant MeSH terms: