Acute Pain Caused by Paclitaxel in Patients With Cancer
Study Details
Study Description
Brief Summary
RATIONALE: Gathering information over time from patients receiving paclitaxel for cancer may help doctors learn more about pain caused by paclitaxel and plan the best treatment.
PURPOSE: This clinical trial is studying acute pain caused by paclitaxel in patients with cancer.
Condition or Disease | Intervention/Treatment | Phase |
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|
Detailed Description
OBJECTIVES:
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To describe the incidence and characteristics of and change in pain related to paclitaxel infusions over several courses in patients receiving paclitaxel weekly or every 2-4 weeks with or without neurotoxic chemotherapy.
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To investigate the association between paclitaxel-induced acute pain syndrome symptoms and eventual chemotherapy-induced neuropathy.
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To perform exome-sequencing analysis and identify genetic variants that predict paclitaxel- induced peripheral neuropathy.
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To identify clinical phenotypes associated with paclitaxel toxicity (i.e., acute pain syndrome and neuropathy).
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To explore whether there are any evident differences between results seen in the majority Caucasian population and the minority populations.
OUTLINE: This is a multicenter study. Patients are grouped according to paclitaxel dosing schedule (weekly vs every 2-4 weeks) and concurrent use of neurotoxic agent (yes vs no).
Blood samples are collected at baseline for correlative laboratory studies, including genetic biomarker and polymorphism studies.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Group I Patients complete pain questionnaires at baseline, 2-8 days after each weekly paclitaxel treatment given in combination with a neurotoxic agent, and then monthly for 1 year. Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected. |
Behavioral: pain questionnaires
|
Group II Patients complete pain questionnaires at baseline, 2-8 days after each weekly paclitaxel treatment not given in combination with a neurotoxic agent, and then monthly for 1 year. Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected. |
Behavioral: pain questionnaires
|
Group III Patients complete pain questionnaires at baseline, 2-8 days after each 2-4 week paclitaxel treatment given in combination with a neurotoxic agent, and then monthly for 1 year. Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected. |
Behavioral: pain questionnaires
|
Group IV Patients complete pain questionnaires at baseline, 2-8 days after each 2-4 week paclitaxel treatment not given in combination with a neurotoxic agent, and then monthly for 1 year. Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected. |
Behavioral: pain questionnaires
|
Outcome Measures
Primary Outcome Measures
- Maximum of the worst pain scores from the initiation of paclitaxel therapy (day 1) until day 7 (first week of therapy) [Up to day 7]
Secondary Outcome Measures
- Maximum of the average pain score [Up to 12 months]
- Area under the curve of worst, average, and least pain [Up to 12 months]
- Worst pain reported for the overall week [Up to 12 months]
- Rate of non-prescription pain medication use [Up to 12 months]
- Rate of opioid use [Up to 12 months]
- Rate of other pain therapy use [Up to 12 months]
- Correlation of the worst pain score for the first dose of therapy with subsequent neuropathy scores [Up to 12 months]
Eligibility Criteria
Criteria
DISEASE CHARACTERISTICS:
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Diagnosis of cancer
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Planning to receive paclitaxel IV (excluding paclitaxel albumin-stabilized nanoparticle formulation [nab-paclitaxel]) according to one of the following dosing schedules:
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At least 175 mg/m^2 at 2-4 week intervals (course duration of 2, 3, or 4 weeks, respectively)
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70-90 mg/m^2 weekly (3 out of 4 weeks allowed)
PATIENT CHARACTERISTICS:
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ECOG performance status 0-1
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Life expectancy > 6 months
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Able to complete questionnaires (alone or with assistance)
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Willing to provide required biological specimens
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No prior or concurrent peripheral neuropathy (from diabetes or other causes)
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No prior or concurrent fibromyalgia
PRIOR CONCURRENT THERAPY:
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See Disease Characteristics
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No prior paclitaxel or neurotoxic chemotherapy drugs, including other taxanes, platinum agents, vinca alkaloids, or epothilones
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No concurrent neutrophil colony-stimulating factor therapy
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Aurora Presbyterian Hospital | Aurora | Colorado | United States | 80012 |
2 | Boulder Community Hospital | Boulder | Colorado | United States | 80301-9019 |
3 | Penrose Cancer Center at Penrose Hospital | Colorado Springs | Colorado | United States | 80933 |
4 | St. Anthony Central Hospital | Denver | Colorado | United States | 80204 |
5 | Porter Adventist Hospital | Denver | Colorado | United States | 80210 |
6 | Presbyterian - St. Luke's Medical Center | Denver | Colorado | United States | 80218 |
7 | St. Joseph Hospital | Denver | Colorado | United States | 80218 |
8 | Rose Medical Center | Denver | Colorado | United States | 80220 |
9 | CCOP - Colorado Cancer Research Program | Denver | Colorado | United States | 80224-2522 |
10 | Swedish Medical Center | Englewood | Colorado | United States | 80110 |
11 | St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center | Grand Junction | Colorado | United States | 81502 |
12 | North Colorado Medical Center | Greeley | Colorado | United States | 80631 |
13 | Littleton Adventist Hospital | Littleton | Colorado | United States | 80122 |
14 | Sky Ridge Medical Center | Lone Tree | Colorado | United States | 80124 |
15 | Hope Cancer Care Center at Longmont United Hospital | Longmont | Colorado | United States | 80501 |
16 | McKee Medical Center | Loveland | Colorado | United States | 80539 |
17 | Parker Adventist Hospital | Parker | Colorado | United States | 80138 |
18 | St. Mary - Corwin Regional Medical Center | Pueblo | Colorado | United States | 81004 |
19 | North Suburban Medical Center | Thornton | Colorado | United States | 80229 |
20 | Exempla Lutheran Medical Center | Wheat Ridge | Colorado | United States | 80033 |
21 | Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center | Hartford | Connecticut | United States | 06105 |
22 | Kapiolani Medical Center at Pali Momi | Aiea | Hawaii | United States | 96701 |
23 | Cancer Research Center of Hawaii | Honolulu | Hawaii | United States | 96813 |
24 | OnCare Hawaii, Incorporated - Lusitana | Honolulu | Hawaii | United States | 96813 |
25 | Queen's Cancer Institute at Queen's Medical Center | Honolulu | Hawaii | United States | 96813 |
26 | Straub Clinic and Hospital, Incorporated | Honolulu | Hawaii | United States | 96813 |
27 | Hawaii Medical Center - East | Honolulu | Hawaii | United States | 96817 |
28 | OnCare Hawaii, Incorporated - Kuakini | Honolulu | Hawaii | United States | 96817 |
29 | Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | United States | 96826 |
30 | Tripler Army Medical Center | Honolulu | Hawaii | United States | 96859 |
31 | Kauai Medical Clinic | Lihue | Hawaii | United States | 96766 |
32 | Maui Memorial Medical Center | Wailuku | Hawaii | United States | 96793 |
33 | Pacific Cancer Institute - Maui | Wailuku | Hawaii | United States | 96793 |
34 | Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | Boise | Idaho | United States | 83706 |
35 | Illinois CancerCare - Bloomington | Bloomington% | Illinois | United States | 61701 |
36 | St. Joseph Medical Center | Bloomington | Illinois | United States | 61701 |
37 | Graham Hospital | Canton | Illinois | United States | 61520 |
38 | Illinois CancerCare - Canton | Canton | Illinois | United States | 61520 |
39 | Illinois CancerCare - Carthage | Carthage | Illinois | United States | 62321 |
40 | Memorial Hospital | Carthage | Illinois | United States | 62321 |
41 | Eureka Community Hospital | Eureka | Illinois | United States | 61530 |
42 | Illinois CancerCare - Eureka | Eureka | Illinois | United States | 61530 |
43 | Galesburg Clinic, PC | Galesburg | Illinois | United States | 61401 |
44 | Illinois CancerCare - Galesburg | Galesburg | Illinois | United States | 61401 |
45 | Illinois CancerCare - Havana | Havana | Illinois | United States | 62644 |
46 | Mason District Hospital | Havana | Illinois | United States | 62644 |
47 | Illinois CancerCare - Kewanee Clinic | Kewanee | Illinois | United States | 61443 |
48 | Illinois CancerCare - Macomb | Macomb | Illinois | United States | 61455 |
49 | McDonough District Hospital | Macomb | Illinois | United States | 61455 |
50 | Trinity Cancer Center at Trinity Medical Center - 7th Street Campus | Moline | Illinois | United States | 61265 |
51 | Moline | Illinois | United States | 61265 | |
52 | Illinois CancerCare - Monmouth | Monmouth | Illinois | United States | 61462 |
53 | OSF Holy Family Medical Center | Monmouth | Illinois | United States | 61462 |
54 | BroMenn Regional Medical Center | Normal | Illinois | United States | 61761 |
55 | Community Cancer Center | Normal | Illinois | United States | 61761 |
56 | Illinois CancerCare - Community Cancer Center | Normal | Illinois | United States | 61761 |
57 | Community Hospital of Ottawa | Ottawa | Illinois | United States | 61350 |
58 | Oncology Hematology Associates of Central Illinois, PC - Ottawa | Ottawa | Illinois | United States | 61350 |
59 | Cancer Treatment Center at Pekin Hospital | Pekin | Illinois | United States | 61554 |
60 | Illinois CancerCare - Pekin | Pekin | Illinois | United States | 61603 |
61 | Proctor Hospital | Peoria | Illinois | United States | 61614 |
62 | CCOP - Illinois Oncology Research Association | Peoria | Illinois | United States | 61615 |
63 | Oncology Hematology Associates of Central Illinois, PC - Peoria | Peoria | Illinois | United States | 61615 |
64 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
65 | OSF St. Francis Medical Center | Peoria | Illinois | United States | 61637 |
66 | Illinois CancerCare - Peru | Peru | Illinois | United States | 61354 |
67 | Illinois Valley Community Hospital | Peru | Illinois | United States | 61354 |
68 | Illinois CancerCare - Princeton | Princeton | Illinois | United States | 61356 |
69 | Perry Memorial Hospital | Princeton | Illinois | United States | 61356 |
70 | Illinois CancerCare - Spring Valley | Spring Valley | Illinois | United States | 61362 |
71 | Michiana Hematology-Oncology, PC - Elkhart | Elkhart | Indiana | United States | 46514 |
72 | Elkhart General Hospital | Elkhart | Indiana | United States | 46515 |
73 | Howard Community Hospital | Kokomo | Indiana | United States | 46904 |
74 | Center for Cancer Therapy at LaPorte Hospital and Health Services | La Porte | Indiana | United States | 46350 |
75 | Michiana Hematology-Oncology, PC - South Bend | Mishawaka | Indiana | United States | 46545-1470 |
76 | Saint Joseph Regional Medical Center | Mishawaka | Indiana | United States | 46545-1470 |
77 | Michiana Hematology Oncology PC - Plymouth | Plymouth | Indiana | United States | 46563 |
78 | CCOP - Northern Indiana CR Consortium | South Bend | Indiana | United States | 46601 |
79 | Memorial Hospital of South Bend | South Bend | Indiana | United States | 46601 |
80 | Michiana Hematology Oncology PC - La Porte | Westville | Indiana | United States | 46391 |
81 | McFarland Clinic, PC | Ames | Iowa | United States | 50010 |
82 | Bettendorf | Iowa | United States | 52722 | |
83 | Cedar Rapids Oncology Associates | Cedar Rapids | Iowa | United States | 52403 |
84 | Mercy Regional Cancer Center at Mercy Medical Center | Cedar Rapids | Iowa | United States | 52403 |
85 | Medical Oncology and Hematology Associates - West Des Moines | Clive | Iowa | United States | 50325 |
86 | CCOP - Iowa Oncology Research Association | Des Moines | Iowa | United States | 50309 |
87 | John Stoddard Cancer Center at Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
88 | Medical Oncology and Hematology Associates at John Stoddard Cancer Center | Des Moines | Iowa | United States | 50309 |
89 | Medical Oncology and Hematology Associates at Mercy Cancer Center | Des Moines | Iowa | United States | 50314 |
90 | Mercy Cancer Center at Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
91 | John Stoddard Cancer Center at Iowa Lutheran Hospital | Des Moines | Iowa | United States | 50316 |
92 | Mercy Cancer Center at Mercy Medical Center - North Iowa | Mason City | Iowa | United States | 50401 |
93 | McCreery Cancer Center at Ottumwa Regional | Ottumwa | Iowa | United States | 52501 |
94 | Siouxland Hematology-Oncology Associates, LLP | Sioux City | Iowa | United States | 51101 |
95 | Mercy Medical Center - Sioux City | Sioux City | Iowa | United States | 51102 |
96 | St. Luke's Regional Medical Center | Sioux City | Iowa | United States | 51104 |
97 | Cancer Center of Kansas, PA - Chanute | Chanute | Kansas | United States | 66720 |
98 | Cancer Center of Kansas, PA - Dodge City | Dodge City | Kansas | United States | 67801 |
99 | Cancer Center of Kansas, PA - El Dorado | El Dorado | Kansas | United States | 67042 |
100 | Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | United States | 66701 |
101 | Cancer Center of Kansas-Independence | Independence | Kansas | United States | 67301 |
102 | Cancer Center of Kansas, PA - Kingman | Kingman | Kansas | United States | 67068 |
103 | Lawrence Memorial Hospital | Lawrence | Kansas | United States | 66044 |
104 | Cancer Center of Kansas, PA - Liberal | Liberal | Kansas | United States | 67901 |
105 | Cancer Center of Kansas, PA - McPherson | McPherson | Kansas | United States | 67460 |
106 | Cancer Center of Kansas, PA - Newton | Newton | Kansas | United States | 67114 |
107 | Cancer Center of Kansas, PA - Parsons | Parsons | Kansas | United States | 67357 |
108 | Cancer Center of Kansas, PA - Pratt | Pratt | Kansas | United States | 67124 |
109 | Cancer Center of Kansas, PA - Salina | Salina | Kansas | United States | 67401 |
110 | Cancer Center of Kansas, PA - Wellington | Wellington | Kansas | United States | 67152 |
111 | Associates in Womens Health, PA - North Review | Wichita | Kansas | United States | 67208 |
112 | Cancer Center of Kansas, PA - Medical Arts Tower | Wichita | Kansas | United States | 67208 |
113 | Cancer Center of Kansas, PA - Wichita | Wichita | Kansas | United States | 67214 |
114 | CCOP - Wichita | Wichita | Kansas | United States | 67214 |
115 | Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | United States | 67214 |
116 | Cancer Center of Kansas, PA - Winfield | Winfield | Kansas | United States | 67156 |
117 | Ochsner Health Center - Bluebonnet | Baton Rouge | Louisiana | United States | 70809 |
118 | CCOP - Ochsner | New Orleans | Louisiana | United States | 70121 |
119 | Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans | Louisiana | United States | 70121 |
120 | Hickman Cancer Center at Bixby Medical Center | Adrian | Michigan | United States | 49221 |
121 | Saint Joseph Mercy Cancer Center | Ann Arbor | Michigan | United States | 48106-0995 |
122 | CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | United States | 48106 |
123 | Battle Creek Health System Cancer Care Center | Battle Creek | Michigan | United States | 49017 |
124 | Mecosta County Medical Center | Big Rapids | Michigan | United States | 49307 |
125 | Oakwood Cancer Center at Oakwood Hospital and Medical Center | Dearborn | Michigan | United States | 48123-2500 |
126 | Green Bay Oncology, Limited - Escanaba | Escanaba | Michigan | United States | 49431 |
127 | Genesys Hurley Cancer Institute | Flint | Michigan | United States | 48503 |
128 | Hurley Medical Center | Flint | Michigan | United States | 48503 |
129 | Butterworth Hospital at Spectrum Health | Grand Rapids | Michigan | United States | 49503 |
130 | CCOP - Grand Rapids | Grand Rapids | Michigan | United States | 49503 |
131 | Lacks Cancer Center at Saint Mary's Health Care | Grand Rapids | Michigan | United States | 49503 |
132 | Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods | Michigan | United States | 48236 |
133 | Dickinson County Healthcare System | Iron Mountain | Michigan | United States | 49801 |
134 | Foote Memorial Hospital | Jackson | Michigan | United States | 49201 |
135 | Sparrow Regional Cancer Center | Lansing | Michigan | United States | 48912-1811 |
136 | St. Mary Mercy Hospital | Livonia | Michigan | United States | 48154 |
137 | Community Cancer Center of Monroe | Monroe | Michigan | United States | 48162 |
138 | Mercy Memorial Hospital - Monroe | Monroe | Michigan | United States | 48162 |
139 | Mercy General Health Partners | Muskegon | Michigan | United States | 49443 |
140 | St. Joseph Mercy Oakland | Pontiac | Michigan | United States | 48341-2985 |
141 | Mercy Regional Cancer Center at Mercy Hospital | Port Huron | Michigan | United States | 48060 |
142 | Seton Cancer Institute at Saint Mary's - Saginaw | Saginaw | Michigan | United States | 48601 |
143 | Lakeside Cancer Specialists, PLLC | Saint Joseph | Michigan | United States | 49085 |
144 | Lakeland Regional Cancer Care Center - St. Joseph | St. Joseph | Michigan | United States | 49085 |
145 | Munson Medical Center | Traverse City | Michigan | United States | 49684 |
146 | St. John Macomb Hospital | Warren | Michigan | United States | 48093 |
147 | Alexandria | Minnesota | United States | 56308 | |
148 | MeritCare Bemidji | Bemidji | Minnesota | United States | 56601 |
149 | Fairview Ridges Hospital | Burnsville | Minnesota | United States | 55337 |
150 | Mercy and Unity Cancer Center at Mercy Hospital | Coon Rapids | Minnesota | United States | 55433 |
151 | Duluth Clinic Cancer Center - Duluth | Duluth | Minnesota | United States | 55805-1983 |
152 | CCOP - Duluth | Duluth | Minnesota | United States | 55805 |
153 | Miller - Dwan Medical Center | Duluth | Minnesota | United States | 55805 |
154 | Fairview Southdale Hospital | Edina | Minnesota | United States | 55435 |
155 | Mercy and Unity Cancer Center at Unity Hospital | Fridley | Minnesota | United States | 55432 |
156 | Hutchinson Area Health Care | Hutchinson | Minnesota | United States | 55350 |
157 | Immanuel St. Joseph's | Mankato | Minnesota | United States | 56002 |
158 | HealthEast Cancer Care at St. John's Hospital | Maplewood | Minnesota | United States | 55109 |
159 | Minnesota Oncology - Maplewood | Maplewood | Minnesota | United States | 55109 |
160 | Virginia Piper Cancer Institute at Abbott - Northwestern Hospital | Minneapolis | Minnesota | United States | 55407 |
161 | Hennepin County Medical Center - Minneapolis | Minneapolis | Minnesota | United States | 55415 |
162 | New Ulm Medical Center | New Ulm | Minnesota | United States | 56073 |
163 | Humphrey Cancer Center at North Memorial Outpatient Center | Robbinsdale | Minnesota | United States | 55422-2900 |
164 | Mayo Clinic Cancer Center | Rochester | Minnesota | United States | 55905 |
165 | CentraCare Clinic - River Campus | Saint Cloud | Minnesota | United States | 56303 |
166 | Coborn Cancer Center | Saint Cloud | Minnesota | United States | 56303 |
167 | CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | United States | 55416 |
168 | Park Nicollet Cancer Center | Saint Louis Park | Minnesota | United States | 55416 |
169 | United Hospital | Saint Paul | Minnesota | United States | 55102 |
170 | St. Francis Cancer Center at St. Francis Medical Center | Shakopee | Minnesota | United States | 55379 |
171 | Regions Hospital Cancer Care Center | St. Paul | Minnesota | United States | 55101 |
172 | Lakeview Hospital | Stillwater | Minnesota | United States | 55082 |
173 | Ridgeview Medical Center | Waconia | Minnesota | United States | 55387 |
174 | Willmar Cancer Center at Rice Memorial Hospital | Willmar | Minnesota | United States | 56201 |
175 | Minnesota Oncology - Woodbury | Woodbury | Minnesota | United States | 55125 |
176 | Southeast Cancer Center | Cape Girardeau | Missouri | United States | 63703 |
177 | Goldschmidt Cancer Center | Jefferson City | Missouri | United States | 65109 |
178 | Missouri Baptist Cancer Center | Saint Louis | Missouri | United States | 63131 |
179 | Comprehensive Cancer Care, PC | Saint Louis | Missouri | United States | 63141 |
180 | CCOP - Montana Cancer Consortium | Billings | Montana | United States | 59101 |
181 | St. Vincent Healthcare Cancer Care Services | Billings | Montana | United States | 59101 |
182 | Hematology-Oncology Centers of the Northern Rockies - Billings | Billings | Montana | United States | 59102 |
183 | Billings Clinic - Downtown | Billings | Montana | United States | 59107-7000 |
184 | Bozeman Deaconess Cancer Center | Bozeman | Montana | United States | 59715 |
185 | St. James Healthcare Cancer Care | Butte | Montana | United States | 59701 |
186 | Great Falls Clinic - Main Facility | Great Falls | Montana | United States | 59405 |
187 | Sletten Cancer Institute at Benefis Healthcare | Great Falls | Montana | United States | 59405 |
188 | Northern Montana Hospital | Havre | Montana | United States | 59501 |
189 | St. Peter's Hospital | Helena | Montana | United States | 59601 |
190 | Glacier Oncology, PLLC | Kalispell | Montana | United States | 59901 |
191 | Kalispell Medical Oncology at KRMC | Kalispell | Montana | United States | 59901 |
192 | Kalispell Regional Medical Center | Kalispell | Montana | United States | 59901 |
193 | Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | United States | 59807-7877 |
194 | Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | Missoula | Montana | United States | 59807 |
195 | Cancer Resource Center - Lincoln | Lincoln | Nebraska | United States | 68510 |
196 | CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | United States | 68106 |
197 | Immanuel Medical Center | Omaha | Nebraska | United States | 68122 |
198 | Alegant Health Cancer Center at Bergan Mercy Medical Center | Omaha | Nebraska | United States | 68124 |
199 | Lakeside Hospital | Omaha | Nebraska | United States | 68130 |
200 | Creighton University Medical Center | Omaha | Nebraska | United States | 68131-2197 |
201 | Bismarck Cancer Center | Bismarck | North Dakota | United States | 58501 |
202 | Medcenter One Hospital Cancer Care Center | Bismarck | North Dakota | United States | 58501 |
203 | Mid Dakota Clinic, PC | Bismarck | North Dakota | United States | 58501 |
204 | St. Alexius Medical Center Cancer Center | Bismarck | North Dakota | United States | 58502 |
205 | MeritCare Broadway | Fargo | North Dakota | United States | 58102 |
206 | CCOP - MeritCare Hospital | Fargo | North Dakota | United States | 58122 |
207 | Roger Maris Cancer Center at MeritCare Hospital | Fargo | North Dakota | United States | 58122 |
208 | Wood County Oncology Center | Bowling Green | Ohio | United States | 43402 |
209 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
210 | Riverside Methodist Hospital Cancer Care | Columbus | Ohio | United States | 43214-3998 |
211 | CCOP - Columbus | Columbus | Ohio | United States | 43215 |
212 | Grant Medical Center Cancer Care | Columbus | Ohio | United States | 43215 |
213 | Mount Carmel Health - West Hospital | Columbus | Ohio | United States | 43222 |
214 | Doctors Hospital at Ohio Health | Columbus | Ohio | United States | 43228 |
215 | Grady Memorial Hospital | Delaware | Ohio | United States | 43015 |
216 | Community Cancer Center | Elyria | Ohio | United States | 44035 |
217 | Hematology Oncology Center | Elyria | Ohio | United States | 44035 |
218 | Fairfield Medical Center | Lancaster | Ohio | United States | 43130 |
219 | Lima Memorial Hospital | Lima | Ohio | United States | 45804 |
220 | Strecker Cancer Center at Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
221 | Northwest Ohio Oncology Center | Maumee | Ohio | United States | 43537-1839 |
222 | Knox Community Hospital | Mount Vernon | Ohio | United States | 43050 |
223 | Licking Memorial Cancer Care Program at Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
224 | Fisher-Titus Medical Center | Norwalk | Ohio | United States | 44857 |
225 | St. Charles Mercy Hospital | Oregon | Ohio | United States | 43616 |
226 | Toledo Clinic - Oregon | Oregon | Ohio | United States | 43616 |
227 | Southern Ohio Medical Center Cancer Center | Portsmouth | Ohio | United States | 45662 |
228 | North Coast Cancer Care, Incorporated | Sandusky | Ohio | United States | 44870 |
229 | Community Hospital of Springfield and Clark County | Springfield | Ohio | United States | 45505 |
230 | Flower Hospital Cancer Center | Sylvania | Ohio | United States | 43560 |
231 | Mercy Hospital of Tiffin | Tiffin | Ohio | United States | 44883 |
232 | Toledo Hospital | Toledo | Ohio | United States | 43606 |
233 | St. Vincent Mercy Medical Center | Toledo | Ohio | United States | 43608 |
234 | Medical University of Ohio Cancer Center | Toledo | Ohio | United States | 43614 |
235 | CCOP - Toledo Community Hospital | Toledo | Ohio | United States | 43617 |
236 | St. Anne Mercy Hospital | Toledo | Ohio | United States | 43623 |
237 | Toledo Clinic, Incorporated - Main Clinic | Toledo | Ohio | United States | 43623 |
238 | Fulton County Health Center | Wauseon | Ohio | United States | 43567 |
239 | Mount Carmel St. Ann's Cancer Center | Westerville | Ohio | United States | 43081 |
240 | Genesis - Good Samaritan Hospital | Zanesville | Ohio | United States | 43701 |
241 | Natalie Warren Bryant Cancer Center at St. Francis Hospital | Tulsa | Oklahoma | United States | 74136 |
242 | Clackamas Radiation Oncology Center | Clackamas | Oregon | United States | 97015 |
243 | Providence Milwaukie Hospital | Milwaukie | Oregon | United States | 97222 |
244 | Providence Newberg Medical Center | Newberg | Oregon | United States | 97132 |
245 | Willamette Falls Hospital | Oregon City | Oregon | United States | 97045 |
246 | Providence Cancer Center at Providence Portland Medical Center | Portland | Oregon | United States | 97213-2967 |
247 | CCOP - Columbia River Oncology Program | Portland | Oregon | United States | 97225 |
248 | Providence St. Vincent Medical Center | Portland | Oregon | United States | 97225 |
249 | Geisinger Cancer Institute at Geisinger Health | Danville | Pennsylvania | United States | 17822-0001 |
250 | Geisinger Hazleton Cancer Center | Hazleton | Pennsylvania | United States | 18201 |
251 | Geisinger Medical Group - Scenery Park | State College | Pennsylvania | United States | 16801 |
252 | Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center | Wilkes-Barre | Pennsylvania | United States | 18711 |
253 | Rapid City Regional Hospital | Rapid City | South Dakota | United States | 57701 |
254 | Sanford Cancer Center at Sanford USD Medical Center | Sioux Falls | South Dakota | United States | 57117-5039 |
255 | Fredericksburg Oncology, Incorporated | Fredericksburg | Virginia | United States | 22401 |
256 | Virginia Commonwealth University Massey Cancer Center | Richmond | Virginia | United States | 23298-0037 |
257 | CCOP - Virginia Mason Research Center | Seattle | Washington | United States | 98101 |
258 | Virginia Mason Medical Center | Seattle | Washington | United States | 98101 |
259 | Southwest Washington Medical Center Cancer Center | Vancouver | Washington | United States | 98664 |
260 | Marshfield Clinic - Chippewa Center | Chippewa Falls | Wisconsin | United States | 54729 |
261 | Marshfield Clinic Cancer Care at Regional Cancer Center | Eau Claire | Wisconsin | United States | 54701 |
262 | Central Wisconsin Cancer Program at Agnesian HealthCare | Fond du Lac | Wisconsin | United States | 54935 |
263 | Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | United States | 54301-3526 |
264 | Green Bay Oncology, Limited at St. Mary's Hospital | Green Bay | Wisconsin | United States | 54303 |
265 | St. Mary's Hospital Medical Center - Green Bay | Green Bay | Wisconsin | United States | 54303 |
266 | St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | United States | 54307-3508 |
267 | Holy Family Memorial Medical Center Cancer Care Center | Manitowoc | Wisconsin | United States | 54221-1450 |
268 | Bay Area Cancer Care Center at Bay Area Medical Center | Marinette | Wisconsin | United States | 54143 |
269 | Marshfield Clinic - Marshfield Center | Marshfield | Wisconsin | United States | 54449 |
270 | Marshfield Clinic - Lakeland Center | Minocqua | Wisconsin | United States | 54548 |
271 | Green Bay Oncology, Limited - Oconto Falls | Oconto Falls | Wisconsin | United States | 54154 |
272 | Ministry Medical Group at Saint Mary's Hospital | Rhinelander | Wisconsin | United States | 54501 |
273 | Marshfield Clinic - Indianhead Center | Rice Lake | Wisconsin | United States | 54868 |
274 | St. Nicholas Hospital | Sheboygan | Wisconsin | United States | 53081 |
275 | Marshfield Clinic at Saint Michael's Hospital | Stevens Point | Wisconsin | United States | 54481 |
276 | Green Bay Oncology, Limited - Sturgeon Bay | Sturgeon Bay | Wisconsin | United States | 54235 |
277 | Marshfield Clinic - Weston Center | Weston | Wisconsin | United States | 54476 |
278 | Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin | United States | 54494 |
279 | Welch Cancer Center at Sheridan Memorial Hospital | Sheridan | Wyoming | United States | 82801 |
Sponsors and Collaborators
- Alliance for Clinical Trials in Oncology
- National Cancer Institute (NCI)
Investigators
- Principal Investigator: Charles L. Loprinzi, MD, Mayo Clinic
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- NCCTG-N08C1
- NCI-2009-01108
- CDR0000631962